EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000044786 (Gene tree)
Gene ID: 22695
Gene Symbol: Zfp36
Alias: Nup475|Tis11|Tristetraprolin|Ttp|Zfp-36
Full Name: zinc finger protein 36
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Minus strand
Length: 3470 bases
Position: chr7:28376784-28380253
Accession: 99180
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000146830	zf-CCCH	PF00642.24	1.9e-19	1	2
ENSMUSP00000146830	zf-CCCH	PF00642.24	1.9e-19	2	2
ENSMUSP00000057815	zf-CCCH	PF00642.24	2.1e-19	1	2
ENSMUSP00000057815	zf-CCCH	PF00642.24	2.1e-19	2	2

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000209061	-	2465	-	ENSMUSP00000146830	307 (aa)	-	Q9DBE5
ENSMUST00000051241	-	2790	-	ENSMUSP00000057815	319 (aa)	-	P22893

Gene Model

Click here to download ENSMUSG00000044786's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu05166	Human T-cell leukemia virus 1 infection	KEGG
mmu05167	Kaposi sarcoma-associated herpesvirus infection	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000044786's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000044786	Zfp36	100	83.537	ENSG00000128016	ZFP36	98	83.792	Homo_sapiens
ENSMUSG00000044786	Zfp36	100	82.515	ENSAMEG00000008499	ZFP36	100	84.356	Ailuropoda_melanoleuca
ENSMUSG00000044786	Zfp36	100	81.098	ENSANAG00000034306	ZFP36	98	80.793	Aotus_nancymaae
ENSMUSG00000044786	Zfp36	100	79.205	ENSBTAG00000008573	ZFP36	100	81.288	Bos_taurus
ENSMUSG00000044786	Zfp36	100	81.098	ENSCJAG00000014156	ZFP36	98	80.793	Callithrix_jacchus
ENSMUSG00000044786	Zfp36	100	79.141	ENSCAFG00000005530	ZFP36	100	80.368	Canis_familiaris
ENSMUSG00000044786	Zfp36	100	80.368	ENSCAFG00020015861	ZFP36	98	81.595	Canis_lupus_dingo
ENSMUSG00000044786	Zfp36	100	79.205	ENSCHIG00000023209	ZFP36	100	80.982	Capra_hircus
ENSMUSG00000044786	Zfp36	100	83.178	ENSCPOG00000038352	ZFP36	100	80.685	Cavia_porcellus
ENSMUSG00000044786	Zfp36	100	80.793	ENSCCAG00000034094	ZFP36	98	80.488	Cebus_capucinus
ENSMUSG00000044786	Zfp36	100	82.875	ENSCATG00000039148	ZFP36	98	84.404	Cercocebus_atys
ENSMUSG00000044786	Zfp36	100	79.814	ENSCLAG00000014820	ZFP36	100	80.124	Chinchilla_lanigera
ENSMUSG00000044786	Zfp36	100	82.875	ENSCSAG00000003862	ZFP36	98	84.404	Chlorocebus_sabaeus
ENSMUSG00000044786	Zfp36	100	44.000	ENSCPBG00000018753	ZFP36	54	51.010	Chrysemys_picta_bellii
ENSMUSG00000044786	Zfp36	100	82.569	ENSCANG00000010605	ZFP36	98	84.098	Colobus_angolensis_palliatus
ENSMUSG00000044786	Zfp36	100	90.741	ENSCGRG00001007290	Zfp36	100	89.506	Cricetulus_griseus_chok1gshd
ENSMUSG00000044786	Zfp36	99	91.586	ENSCGRG00000019003	Zfp36	99	90.291	Cricetulus_griseus_crigri
ENSMUSG00000044786	Zfp36	81	74.906	ENSDNOG00000033326	ZFP36	90	77.444	Dasypus_novemcinctus
ENSMUSG00000044786	Zfp36	99	85.902	ENSDORG00000013487	Zfp36	100	83.282	Dipodomys_ordii
ENSMUSG00000044786	Zfp36	100	83.129	ENSEASG00005012802	ZFP36	100	84.969	Equus_asinus_asinus
ENSMUSG00000044786	Zfp36	100	83.121	ENSECAG00000033926	ZFP36	100	83.129	Equus_caballus
ENSMUSG00000044786	Zfp36	100	82.569	ENSFCAG00000045634	ZFP36	98	84.356	Felis_catus
ENSMUSG00000044786	Zfp36	100	82.298	ENSFDAG00000008740	ZFP36	100	80.124	Fukomys_damarensis
ENSMUSG00000044786	Zfp36	74	52.227	ENSGAGG00000021476	ZFP36	55	49.756	Gopherus_agassizii
ENSMUSG00000044786	Zfp36	100	83.232	ENSGGOG00000014399	ZFP36	98	83.486	Gorilla_gorilla
ENSMUSG00000044786	Zfp36	100	82.919	ENSHGLG00000007955	ZFP36	100	81.366	Heterocephalus_glaber_female
ENSMUSG00000044786	Zfp36	100	77.950	ENSHGLG00100017184	ZFP36	100	75.466	Heterocephalus_glaber_male
ENSMUSG00000044786	Zfp36	100	89.342	ENSSTOG00000019840	ZFP36	98	90.000	Ictidomys_tridecemlineatus
ENSMUSG00000044786	Zfp36	100	82.663	ENSJJAG00000010452	-	100	87.346	Jaculus_jaculus
ENSMUSG00000044786	Zfp36	100	80.186	ENSJJAG00000011735	-	100	84.877	Jaculus_jaculus
ENSMUSG00000044786	Zfp36	100	82.875	ENSMFAG00000000900	ZFP36	98	84.404	Macaca_fascicularis
ENSMUSG00000044786	Zfp36	100	82.875	ENSMMUG00000038702	ZFP36	98	84.404	Macaca_mulatta
ENSMUSG00000044786	Zfp36	100	82.875	ENSMNEG00000039734	ZFP36	98	84.404	Macaca_nemestrina
ENSMUSG00000044786	Zfp36	100	83.180	ENSMLEG00000041066	ZFP36	98	84.709	Mandrillus_leucophaeus
ENSMUSG00000044786	Zfp36	99	88.852	ENSMAUG00000021250	Zfp36	100	86.875	Mesocricetus_auratus
ENSMUSG00000044786	Zfp36	100	81.098	ENSMICG00000026814	ZFP36	98	82.622	Microcebus_murinus
ENSMUSG00000044786	Zfp36	100	93.438	ENSMOCG00000014548	Zfp36	100	93.438	Microtus_ochrogaster
ENSMUSG00000044786	Zfp36	100	54.444	ENSMODG00000013494	ZFP36	96	55.211	Monodelphis_domestica
ENSMUSG00000044786	Zfp36	100	98.746	MGP_CAROLIEiJ_G0029444	Zfp36	100	98.746	Mus_caroli
ENSMUSG00000044786	Zfp36	100	98.433	MGP_PahariEiJ_G0012680	Zfp36	100	98.433	Mus_pahari
ENSMUSG00000044786	Zfp36	100	99.687	MGP_SPRETEiJ_G0030542	Zfp36	100	99.687	Mus_spretus
ENSMUSG00000044786	Zfp36	100	80.183	ENSMPUG00000017726	ZFP36	100	83.537	Mustela_putorius_furo
ENSMUSG00000044786	Zfp36	100	79.077	ENSMLUG00000002942	ZFP36	100	80.308	Myotis_lucifugus
ENSMUSG00000044786	Zfp36	100	86.604	ENSNGAG00000019033	Zfp36	98	86.604	Nannospalax_galili
ENSMUSG00000044786	Zfp36	100	79.511	ENSNLEG00000014418	ZFP36	98	81.040	Nomascus_leucogenys
ENSMUSG00000044786	Zfp36	88	59.862	ENSMEUG00000010317	ZFP36	99	55.319	Notamacropus_eugenii
ENSMUSG00000044786	Zfp36	100	83.178	ENSODEG00000016693	ZFP36	100	83.178	Octodon_degus
ENSMUSG00000044786	Zfp36	99	86.842	ENSOCUG00000003400	ZFP36	100	84.013	Oryctolagus_cuniculus
ENSMUSG00000044786	Zfp36	100	85.209	ENSOGAG00000034231	ZFP36	100	85.139	Otolemur_garnettii
ENSMUSG00000044786	Zfp36	100	77.064	ENSOARG00000006068	ZFP36	100	77.607	Ovis_aries
ENSMUSG00000044786	Zfp36	100	83.232	ENSPPAG00000032232	ZFP36	98	83.486	Pan_paniscus
ENSMUSG00000044786	Zfp36	100	83.439	ENSPPRG00000013318	ZFP36	98	84.663	Panthera_pardus
ENSMUSG00000044786	Zfp36	100	83.129	ENSPTIG00000010660	ZFP36	98	84.356	Panthera_tigris_altaica
ENSMUSG00000044786	Zfp36	100	83.232	ENSPTRG00000010968	ZFP36	98	83.486	Pan_troglodytes
ENSMUSG00000044786	Zfp36	100	82.875	ENSPANG00000007276	ZFP36	98	84.404	Papio_anubis
ENSMUSG00000044786	Zfp36	100	94.156	ENSPEMG00000007506	Zfp36	100	94.062	Peromyscus_maniculatus_bairdii
ENSMUSG00000044786	Zfp36	97	56.627	ENSPCIG00000010489	ZFP36	97	56.970	Phascolarctos_cinereus
ENSMUSG00000044786	Zfp36	58	85.405	ENSPPYG00000010577	-	87	83.511	Pongo_abelii
ENSMUSG00000044786	Zfp36	100	81.707	ENSPCOG00000016898	ZFP36	98	83.841	Propithecus_coquereli
ENSMUSG00000044786	Zfp36	100	81.902	ENSPVAG00000011124	ZFP36	100	82.822	Pteropus_vampyrus
ENSMUSG00000044786	Zfp36	100	96.753	ENSRNOG00000058388	Zfp36	98	96.562	Rattus_norvegicus
ENSMUSG00000044786	Zfp36	100	82.569	ENSRBIG00000038385	ZFP36	98	84.098	Rhinopithecus_bieti
ENSMUSG00000044786	Zfp36	100	82.569	ENSRROG00000042031	ZFP36	98	84.098	Rhinopithecus_roxellana
ENSMUSG00000044786	Zfp36	100	82.317	ENSSBOG00000033740	ZFP36	98	80.488	Saimiri_boliviensis_boliviensis
ENSMUSG00000044786	Zfp36	85	57.093	ENSSHAG00000009151	-	99	56.446	Sarcophilus_harrisii
ENSMUSG00000044786	Zfp36	88	50.512	ENSSPUG00000011402	ZFP36	87	44.785	Sphenodon_punctatus
ENSMUSG00000044786	Zfp36	100	83.492	ENSSSCG00000028056	ZFP36	100	84.709	Sus_scrofa
ENSMUSG00000044786	Zfp36	97	86.557	ENSTBEG00000005948	ZFP36	100	86.120	Tupaia_belangeri
ENSMUSG00000044786	Zfp36	100	80.831	ENSTTRG00000003564	ZFP36	100	81.538	Tursiops_truncatus
ENSMUSG00000044786	Zfp36	100	82.515	ENSUAMG00000009986	ZFP36	100	84.356	Ursus_americanus
ENSMUSG00000044786	Zfp36	99	82.315	ENSUMAG00000019533	ZFP36	100	82.822	Ursus_maritimus
ENSMUSG00000044786	Zfp36	100	80.255	ENSVVUG00000006271	ZFP36	98	81.288	Vulpes_vulpes
ENSMUSG00000044786	Zfp36	100	43.440	ENSXETG00000002899	zfp36	99	40.407	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	21784977.	IMP	Process
GO:0000122	negative regulation of transcription by RNA polymerase II	-	ISO	Process
GO:0000165	MAPK cascade	24733888.	IDA	Process
GO:0000165	MAPK cascade	22844456.	IMP	Process
GO:0000165	MAPK cascade	-	ISO	Process
GO:0000178	exosome (RNase complex)	-	IEA	Component
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	15814898.	IDA	Process
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	-	ISO	Process
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	15814898.	IDA	Process
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	-	ISO	Process
GO:0000932	P-body	-	ISO	Component
GO:0003677	DNA binding	-	IEA	Function
GO:0003729	mRNA binding	10751406.17288565.27193233.	IDA	Function
GO:0003729	mRNA binding	11782475.	ISO	Function
GO:0003730	mRNA 3'-UTR binding	21873635.	IBA	Function
GO:0003730	mRNA 3'-UTR binding	-	ISO	Function
GO:0005515	protein binding	11886850.14688255.17170118.20595389.21278420.22844456.	IPI	Function
GO:0005634	nucleus	11796723.15814898.22844456.	IDA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005737	cytoplasm	9703499.11796723.15814898.17288565.22844456.24733888.	IDA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	10751406.	IDA	Component
GO:0005829	cytosol	10751406.	ISO	Component
GO:0006357	regulation of transcription by RNA polymerase II	20410487.	IGI	Process
GO:0006402	mRNA catabolic process	10751406.11782475.	ISO	Process
GO:0007275	multicellular organism development	-	IEA	Process
GO:0009611	response to wounding	20166898.	IDA	Process
GO:0009611	response to wounding	-	ISO	Process
GO:0010494	cytoplasmic stress granule	-	ISO	Component
GO:0010837	regulation of keratinocyte proliferation	-	ISO	Process
GO:0017091	AU-rich element binding	10330172.15814898.17288565.20595389.	IDA	Function
GO:0017091	AU-rich element binding	-	ISO	Function
GO:0019899	enzyme binding	-	ISO	Function
GO:0019901	protein kinase binding	-	ISO	Function
GO:0019957	C-C chemokine binding	-	ISO	Function
GO:0030014	CCR4-NOT complex	20595389.	IDA	Component
GO:0031072	heat shock protein binding	-	ISO	Function
GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay	-	ISO	Process
GO:0032680	regulation of tumor necrosis factor production	-	ISO	Process
GO:0032897	negative regulation of viral transcription	-	ISO	Process
GO:0035278	miRNA mediated inhibition of translation	21278420.	IDA	Process
GO:0035556	intracellular signal transduction	7768935.	IDA	Process
GO:0035925	mRNA 3'-UTR AU-rich region binding	11533235.17971298.20410487.22701344.	IDA	Function
GO:0035925	mRNA 3'-UTR AU-rich region binding	-	ISO	Function
GO:0038066	p38MAPK cascade	11533235.	IDA	Process
GO:0042594	response to starvation	-	ISO	Process
GO:0043488	regulation of mRNA stability	15467755.17288565.22701344.	IDA	Process
GO:0043488	regulation of mRNA stability	15634918.	IMP	Process
GO:0043488	regulation of mRNA stability	-	ISO	Process
GO:0044344	cellular response to fibroblast growth factor stimulus	24733888.	IDA	Process
GO:0044344	cellular response to fibroblast growth factor stimulus	-	ISO	Process
GO:0045085	negative regulation of interleukin-2 biosynthetic process	15634918.	IMP	Process
GO:0045600	positive regulation of fat cell differentiation	22701344.	IDA	Process
GO:0045616	regulation of keratinocyte differentiation	-	ISO	Process
GO:0045638	negative regulation of myeloid cell differentiation	11588035.	IMP	Process
GO:0045647	negative regulation of erythrocyte differentiation	-	ISO	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0050728	negative regulation of inflammatory response	8630730.11588035.21784977.	IMP	Process
GO:0050779	RNA destabilization	11588035.	IMP	Process
GO:0051028	mRNA transport	-	ISO	Process
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	21278420.	IDA	Process
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	20595389.	IMP	Process
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	-	ISO	Process
GO:0061014	positive regulation of mRNA catabolic process	15634918.	IMP	Process
GO:0061158	3'-UTR-mediated mRNA destabilization	21873635.	IBA	Process
GO:0061158	3'-UTR-mediated mRNA destabilization	22701344.27193233.	IDA	Process
GO:0061158	3'-UTR-mediated mRNA destabilization	17288565.	IMP	Process
GO:0061158	3'-UTR-mediated mRNA destabilization	-	ISO	Process
GO:0070063	RNA polymerase binding	22844456.	IDA	Function
GO:0070578	RISC-loading complex	-	ISO	Component
GO:0070935	3'-UTR-mediated mRNA stabilization	-	ISO	Process
GO:0071222	cellular response to lipopolysaccharide	9703499.10330172.11533235.	IDA	Process
GO:0071222	cellular response to lipopolysaccharide	22844456.	IMP	Process
GO:0071222	cellular response to lipopolysaccharide	-	ISO	Process
GO:0071356	cellular response to tumor necrosis factor	9703499.	IDA	Process
GO:0071356	cellular response to tumor necrosis factor	-	ISO	Process
GO:0071364	cellular response to epidermal growth factor stimulus	-	ISO	Process
GO:0071385	cellular response to glucocorticoid stimulus	-	ISO	Process
GO:0071889	14-3-3 protein binding	20595389.	IDA	Function
GO:0071889	14-3-3 protein binding	-	ISO	Function
GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	-	ISO	Process
GO:0098745	Dcp1-Dcp2 complex	-	ISO	Component
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	21278420.	IDA	Process
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	-	ISO	Process
GO:1901835	positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA	-	ISO	Process
GO:1902172	regulation of keratinocyte apoptotic process	-	ISO	Process
GO:1904246	negative regulation of polynucleotide adenylyltransferase activity	22844456.	IMP	Process
GO:1904582	positive regulation of intracellular mRNA localization	-	ISO	Process
GO:1990904	ribonucleoprotein complex	10330172.17971298.22844456.	IDA	Component
GO:1990904	ribonucleoprotein complex	-	ISO	Component
GO:2000637	positive regulation of gene silencing by miRNA	-	ISO	Process