EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000046709 (Gene tree)
Gene ID: 26414
Gene Symbol: Mapk10
Alias: C230008H04Rik|JNK3|Serk2|p493F12
Full Name: mitogen-activated protein kinase 10
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 303387 bases
Position: chr5:102907948-103211334
Accession: 1346863
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000143448	RIO1	PF01163.22	0.00033	1	1
ENSMUSP00000143609	RIO1	PF01163.22	0.0006	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000142444	-	265	-	-	- (aa)	-	-
ENSMUST00000152609	-	968	-	-	- (aa)	-	-
ENSMUST00000128869	-	2518	-	ENSMUSP00000143448	178 (aa)	-	A0A0G2JG69
ENSMUST00000086854	-	6630	XM_006534950	ENSMUSP00000084065	464 (aa)	XP_006535013	Q80W80
ENSMUST00000135134	-	342	-	-	- (aa)	-	-
ENSMUST00000136595	-	300	-	-	- (aa)	-	-
ENSMUST00000112848	-	6761	-	ENSMUSP00000108469	494 (aa)	-	E9QN59
ENSMUST00000141573	-	1502	-	ENSMUSP00000142798	173 (aa)	-	A0A0G2JEJ8
ENSMUST00000170792	-	7203	XM_017320890	ENSMUSP00000127193	422 (aa)	XP_017176379	Q80W82
ENSMUST00000112847	-	7196	XM_011249450	ENSMUSP00000108468	464 (aa)	XP_011247752	Q8C9D4
ENSMUST00000112846	-	2617	-	ENSMUSP00000108467	418 (aa)	-	Q3TQZ7
ENSMUST00000133069	-	2732	-	ENSMUSP00000143609	252 (aa)	-	A0A0G2JGL2

Gene Model

Click here to download ENSMUSG00000046709's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu01522	Endocrine resistance	KEGG
mmu04010	MAPK signaling pathway	KEGG
mmu04012	ErbB signaling pathway	KEGG
mmu04014	Ras signaling pathway	KEGG
mmu04024	cAMP signaling pathway	KEGG
mmu04068	FoxO signaling pathway	KEGG
mmu04071	Sphingolipid signaling pathway	KEGG
mmu04137	Mitophagy - animal	KEGG
mmu04140	Autophagy - animal	KEGG
mmu04141	Protein processing in endoplasmic reticulum	KEGG
mmu04210	Apoptosis	KEGG
mmu04215	Apoptosis - multiple species	KEGG
mmu04217	Necroptosis	KEGG
mmu04310	Wnt signaling pathway	KEGG
mmu04380	Osteoclast differentiation	KEGG
mmu04510	Focal adhesion	KEGG
mmu04530	Tight junction	KEGG
mmu04620	Toll-like receptor signaling pathway	KEGG
mmu04621	NOD-like receptor signaling pathway	KEGG
mmu04622	RIG-I-like receptor signaling pathway	KEGG
mmu04625	C-type lectin receptor signaling pathway	KEGG
mmu04657	IL-17 signaling pathway	KEGG
mmu04658	Th1 and Th2 cell differentiation	KEGG
mmu04659	Th17 cell differentiation	KEGG
mmu04664	Fc epsilon RI signaling pathway	KEGG
mmu04668	TNF signaling pathway	KEGG
mmu04722	Neurotrophin signaling pathway	KEGG
mmu04723	Retrograde endocannabinoid signaling	KEGG
mmu04728	Dopaminergic synapse	KEGG
mmu04750	Inflammatory mediator regulation of TRP channels	KEGG
mmu04910	Insulin signaling pathway	KEGG
mmu04912	GnRH signaling pathway	KEGG
mmu04914	Progesterone-mediated oocyte maturation	KEGG
mmu04917	Prolactin signaling pathway	KEGG
mmu04920	Adipocytokine signaling pathway	KEGG
mmu04926	Relaxin signaling pathway	KEGG
mmu04930	Type II diabetes mellitus	KEGG
mmu04931	Insulin resistance	KEGG
mmu04932	Non-alcoholic fatty liver disease (NAFLD)	KEGG
mmu04933	AGE-RAGE signaling pathway in diabetic complications	KEGG
mmu05132	Salmonella infection	KEGG
mmu05133	Pertussis	KEGG
mmu05142	Chagas disease (American trypanosomiasis)	KEGG
mmu05145	Toxoplasmosis	KEGG
mmu05152	Tuberculosis	KEGG
mmu05161	Hepatitis B	KEGG
mmu05162	Measles	KEGG
mmu05166	Human T-cell leukemia virus 1 infection	KEGG
mmu05167	Kaposi sarcoma-associated herpesvirus infection	KEGG
mmu05169	Epstein-Barr virus infection	KEGG
mmu05170	Human immunodeficiency virus 1 infection	KEGG
mmu05200	Pathways in cancer	KEGG
mmu05210	Colorectal cancer	KEGG
mmu05212	Pancreatic cancer	KEGG
mmu05231	Choline metabolism in cancer	KEGG
mmu05418	Fluid shear stress and atherosclerosis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000046709's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSMUSG00000046709	Mapk10	84	37.908	ENSMUSG00000020389	Cdkl3	90	35.556
ENSMUSG00000046709	Mapk10	71	33.333	ENSMUSG00000034974	Dapk3	73	30.653
ENSMUSG00000046709	Mapk10	86	30.380	ENSMUSG00000024969	Mark2	90	30.769

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000046709	Mapk10	97	98.776	ENSG00000109339	MAPK10	100	100.000	Homo_sapiens
ENSMUSG00000046709	Mapk10	94	98.204	ENSAPOG00000022997	mapk10	89	97.619	Acanthochromis_polyacanthus
ENSMUSG00000046709	Mapk10	92	79.878	ENSACIG00000020826	mapk8b	53	78.049	Amphilophus_citrinellus
ENSMUSG00000046709	Mapk10	97	98.367	ENSANAG00000016888	MAPK10	100	98.367	Aotus_nancymaae
ENSMUSG00000046709	Mapk10	93	99.398	ENSCAFG00020009946	MAPK10	97	99.517	Canis_lupus_dingo
ENSMUSG00000046709	Mapk10	97	98.776	ENSTSYG00000005950	MAPK10	100	98.776	Carlito_syrichta
ENSMUSG00000046709	Mapk10	96	98.830	ENSCGRG00000000941	Mapk10	99	99.057	Cricetulus_griseus_crigri
ENSMUSG00000046709	Mapk10	93	99.394	ENSEASG00005012811	MAPK10	96	99.515	Equus_asinus_asinus
ENSMUSG00000046709	Mapk10	92	97.561	ENSELUG00000020634	-	79	98.049	Esox_lucius
ENSMUSG00000046709	Mapk10	97	98.367	ENSFCAG00000002234	MAPK10	100	98.367	Felis_catus
ENSMUSG00000046709	Mapk10	99	95.480	ENSJJAG00000022409	Mapk10	100	95.480	Jaculus_jaculus
ENSMUSG00000046709	Mapk10	99	99.200	ENSMAUG00000017023	Mapk10	99	99.200	Mesocricetus_auratus
ENSMUSG00000046709	Mapk10	99	97.175	ENSMOCG00000014375	Mapk10	99	97.175	Microtus_ochrogaster
ENSMUSG00000046709	Mapk10	100	99.206	MGP_CAROLIEiJ_G0027465	Mapk10	100	99.206	Mus_caroli
ENSMUSG00000046709	Mapk10	99	99.602	MGP_PahariEiJ_G0017243	Mapk10	99	99.602	Mus_pahari
ENSMUSG00000046709	Mapk10	100	99.206	MGP_SPRETEiJ_G0028462	Mapk10	100	99.206	Mus_spretus
ENSMUSG00000046709	Mapk10	97	98.837	ENSNGAG00000009045	Mapk10	97	98.837	Nannospalax_galili
ENSMUSG00000046709	Mapk10	97	98.776	ENSPPAG00000042829	MAPK10	100	98.776	Pan_paniscus
ENSMUSG00000046709	Mapk10	97	98.367	ENSPPRG00000004716	MAPK10	100	98.367	Panthera_pardus
ENSMUSG00000046709	Mapk10	97	98.367	ENSPTIG00000019645	MAPK10	100	98.367	Panthera_tigris_altaica
ENSMUSG00000046709	Mapk10	97	98.256	ENSPEMG00000011205	Mapk10	97	98.256	Peromyscus_maniculatus_bairdii
ENSMUSG00000046709	Mapk10	95	97.041	ENSPNAG00000020204	mapk10	88	97.619	Pygocentrus_nattereri
ENSMUSG00000046709	Mapk10	96	98.235	ENSSPUG00000003136	MAPK10	95	98.578	Sphenodon_punctatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	-	ISO	Process
GO:0000166	nucleotide binding	-	IEA	Function
GO:0004672	protein kinase activity	-	IEA	Function
GO:0004674	protein serine/threonine kinase activity	-	IEA	Function
GO:0004705	JUN kinase activity	21873635.	IBA	Function
GO:0004705	JUN kinase activity	9349820.	IDA	Function
GO:0004705	JUN kinase activity	-	ISO	Function
GO:0004707	MAP kinase activity	21873635.	IBA	Function
GO:0005515	protein binding	10471813.10523642.15767678.17724133.	IPI	Function
GO:0005524	ATP binding	-	ISO	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	17724133.	IDA	Component
GO:0005739	mitochondrion	17724133.	IDA	Component
GO:0005886	plasma membrane	17724133.	IDA	Component
GO:0006468	protein phosphorylation	22441692.	IMP	Process
GO:0006468	protein phosphorylation	-	ISO	Process
GO:0007254	JNK cascade	21873635.	IBA	Process
GO:0007254	JNK cascade	9349820.	IDA	Process
GO:0007254	JNK cascade	-	ISO	Process
GO:0007258	JUN phosphorylation	-	ISO	Process
GO:0009416	response to light stimulus	22441692.	IMP	Process
GO:0010468	regulation of gene expression	21873635.	IBA	Process
GO:0014069	postsynaptic density	17114649.	IDA	Component
GO:0016020	membrane	-	IEA	Component
GO:0016301	kinase activity	-	IEA	Function
GO:0016310	phosphorylation	-	IEA	Process
GO:0016740	transferase activity	-	IEA	Function
GO:0035556	intracellular signal transduction	21873635.	IBA	Process
GO:0042752	regulation of circadian rhythm	22441692.	IMP	Process
GO:0043005	neuron projection	-	ISO	Component
GO:0043204	perikaryon	-	ISO	Component
GO:0045475	locomotor rhythm	22441692.	IMP	Process
GO:0048511	rhythmic process	-	IEA	Process
GO:0071310	cellular response to organic substance	21873635.	IBA	Process
GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	-	ISO	Process
GO:0098978	glutamatergic synapse	-	ISO	Component
GO:0099003	vesicle-mediated transport in synapse	-	ISO	Process