EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000049932 (Gene tree)
Gene ID: 15270
Gene Symbol: H2afx
Alias: H2A.X|H2ax|Hist5-2ax|gammaH2ax
Full Name: H2A histone family%2C member X
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 1384
Position: chr9: 44334694-44336077
Accession: 102688
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
25993413	Label-Free Protein RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression	IC & MEF	2015	Boucas J	DOI: 10.1371/journal.pone.0125745
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000052686	-	1384	-	ENSMUSP00000051432	143 (aa)	-	P27661

Gene Model

Click here to download ENSMUSG00000049932's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04217	Necroptosis	KEGG
mmu05034	Alcoholism	KEGG
mmu05322	Systemic lupus erythematosus	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000049932's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000049932	H2afx	73	90.476	WBGene00001942	his-68	96	87.805	Caenorhabditis_elegans
ENSMUSG00000049932	H2afx	89	75.591	YDR225W	HTA1	97	71.429	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000077	DNA damage checkpoint	11934988.	IMP	Process
GO:0000724	double-strand break repair via homologous recombination	11934988.	IMP	Process
GO:0000781	chromosome, telomeric region	-	ISO	Component
GO:0000785	chromatin	11934988.15657431.18283110.18694567.27760146.	IDA	Component
GO:0000786	nucleosome	-	IEA	Component
GO:0000790	nuclear chromatin	21873635.	IBA	Component
GO:0000790	nuclear chromatin	17696610.	IDA	Component
GO:0000794	condensed nuclear chromosome	20551173.22164254.22711701.23555294.26490168.	IDA	Component
GO:0001673	male germ cell nucleus	17696610.	IDA	Component
GO:0001741	XY body	18070917.18316482.19074312.20577743.21539824.22699483.22854038.23133398.23810942.25634095.25675407.26358182.	IDA	Component
GO:0003677	DNA binding	21873635.	IBA	Function
GO:0003684	damaged DNA binding	11934988.	IDA	Function
GO:0005515	protein binding	17304220.19092802.20360685.25634095.	IPI	Function
GO:0005634	nucleus	14611631.17475928.17912366.19176879.20360685.20516196.21911473.21991325.22297488.	IDA	Component
GO:0005634	nucleus	11331621.15604234.	ISO	Component
GO:0005654	nucleoplasm	-	ISO	Component
GO:0005657	replication fork	15364958.	IDA	Component
GO:0005694	chromosome	23039116.	IDA	Component
GO:0005813	centrosome	-	ISO	Component
GO:0006281	DNA repair	15364958.	IDA	Process
GO:0006281	DNA repair	11934988.	IMP	Process
GO:0006310	DNA recombination	-	IEA	Process
GO:0006325	chromatin organization	21873635.	IBA	Process
GO:0006974	cellular response to DNA damage stimulus	21873635.	IBA	Process
GO:0006974	cellular response to DNA damage stimulus	-	ISO	Process
GO:0007049	cell cycle	-	IEA	Process
GO:0007283	spermatogenesis	11934988.	IMP	Process
GO:0016607	nuclear speck	-	ISO	Component
GO:0019899	enzyme binding	-	ISO	Function
GO:0035861	site of double-strand break	22699483.23133398.	IDA	Component
GO:0035861	site of double-strand break	-	ISO	Component
GO:0042393	histone binding	-	ISO	Function
GO:0046982	protein heterodimerization activity	-	IEA	Function
GO:0051321	meiotic cell cycle	-	IEA	Process
GO:0071480	cellular response to gamma radiation	-	ISO	Process
GO:0090734	site of DNA damage	-	ISO	Component