EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000050240 (Gene tree)
Gene ID: 58180
Gene Symbol: Hic2
Alias: HRG22
Full Name: hypermethylated in cancer 2
Gene Type: protein_coding
Species: Mus_musculus
Status: confidence
Strand: Plus strand
Length: 29859 bases
Position: chr16:17233572-17263430
Accession: 1929869
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSMUSP00000087656	zf-C2H2	PF00096.26	7.1e-24	1	4
ENSMUSP00000087656	zf-C2H2	PF00096.26	7.1e-24	2	4
ENSMUSP00000087656	zf-C2H2	PF00096.26	7.1e-24	3	4
ENSMUSP00000087656	zf-C2H2	PF00096.26	7.1e-24	4	4
ENSMUSP00000156293	zf-C2H2	PF00096.26	2.2e-05	1	1
ENSMUSP00000087656	zf-met	PF12874.7	1.3e-09	1	2
ENSMUSP00000087656	zf-met	PF12874.7	1.3e-09	2	2

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000090190	-	6354	-	ENSMUSP00000087656	619 (aa)	-	Q9JLZ6
ENSMUST00000232082	-	2765	-	ENSMUSP00000156293	566 (aa)	-	UPI00000E9EAA

Gene Model

Click here to download ENSMUSG00000050240's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000050240's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000050240	Hic2	100	87.742	ENSG00000169635	HIC2	100	88.065	Homo_sapiens
ENSMUSG00000050240	Hic2	96	56.501	ENSAPOG00000005694	hic2	100	56.800	Acanthochromis_polyacanthus
ENSMUSG00000050240	Hic2	96	55.161	ENSACIG00000018835	hic2	100	55.859	Amphilophus_citrinellus
ENSMUSG00000050240	Hic2	96	56.006	ENSAOCG00000001395	hic2	100	56.958	Amphiprion_ocellaris
ENSMUSG00000050240	Hic2	96	56.006	ENSAPEG00000016621	hic2	100	56.958	Amphiprion_percula
ENSMUSG00000050240	Hic2	96	55.825	ENSATEG00000021233	hic2	100	55.662	Anabas_testudineus
ENSMUSG00000050240	Hic2	96	64.638	ENSAPLG00000002158	HIC2	100	65.517	Anas_platyrhynchos
ENSMUSG00000050240	Hic2	100	87.903	ENSANAG00000027852	HIC2	100	87.903	Aotus_nancymaae
ENSMUSG00000050240	Hic2	96	56.006	ENSACLG00000010236	hic2	100	57.189	Astatotilapia_calliptera
ENSMUSG00000050240	Hic2	99	53.033	ENSAMXG00000024918	hic2	99	56.358	Astyanax_mexicanus
ENSMUSG00000050240	Hic2	64	59.908	ENSAMXG00000030914	hic1l	77	59.908	Astyanax_mexicanus
ENSMUSG00000050240	Hic2	100	79.743	ENSBTAG00000005951	HIC2	100	80.064	Bos_taurus
ENSMUSG00000050240	Hic2	100	88.226	ENSCJAG00000006497	HIC2	100	88.226	Callithrix_jacchus
ENSMUSG00000050240	Hic2	100	88.226	ENSCAFG00000032493	HIC2	100	88.226	Canis_familiaris
ENSMUSG00000050240	Hic2	100	88.226	ENSCAFG00020015055	HIC2	100	88.226	Canis_lupus_dingo
ENSMUSG00000050240	Hic2	100	79.260	ENSCHIG00000007511	HIC2	100	79.904	Capra_hircus
ENSMUSG00000050240	Hic2	100	88.387	ENSTSYG00000031032	HIC2	100	89.194	Carlito_syrichta
ENSMUSG00000050240	Hic2	100	87.581	ENSCPOG00000001134	HIC2	100	87.581	Cavia_porcellus
ENSMUSG00000050240	Hic2	100	88.065	ENSCCAG00000023925	HIC2	100	88.065	Cebus_capucinus
ENSMUSG00000050240	Hic2	100	87.903	ENSCATG00000032567	HIC2	100	88.226	Cercocebus_atys
ENSMUSG00000050240	Hic2	100	87.097	ENSCLAG00000017018	HIC2	100	87.097	Chinchilla_lanigera
ENSMUSG00000050240	Hic2	100	87.742	ENSCSAG00000013356	HIC2	100	88.065	Chlorocebus_sabaeus
ENSMUSG00000050240	Hic2	96	65.512	ENSCPBG00000010464	HIC2	100	66.337	Chrysemys_picta_bellii
ENSMUSG00000050240	Hic2	100	87.419	ENSCANG00000040132	HIC2	100	87.742	Colobus_angolensis_palliatus
ENSMUSG00000050240	Hic2	100	90.645	ENSCGRG00001021159	Hic2	100	91.129	Cricetulus_griseus_chok1gshd
ENSMUSG00000050240	Hic2	100	90.645	ENSCGRG00000006928	Hic2	100	91.129	Cricetulus_griseus_crigri
ENSMUSG00000050240	Hic2	96	54.502	ENSCSEG00000019899	hic2	100	55.591	Cynoglossus_semilaevis
ENSMUSG00000050240	Hic2	96	56.911	ENSCVAG00000019191	hic2	100	57.624	Cyprinodon_variegatus
ENSMUSG00000050240	Hic2	96	57.730	ENSDARG00000100497	hic2	100	57.730	Danio_rerio
ENSMUSG00000050240	Hic2	66	69.672	ENSDARG00000045660	hic1l	64	69.672	Danio_rerio
ENSMUSG00000050240	Hic2	100	84.727	ENSDNOG00000003162	HIC2	100	85.209	Dasypus_novemcinctus
ENSMUSG00000050240	Hic2	100	87.903	ENSDORG00000028360	Hic2	100	87.903	Dipodomys_ordii
ENSMUSG00000050240	Hic2	100	89.516	ENSEASG00005022299	HIC2	100	89.516	Equus_asinus_asinus
ENSMUSG00000050240	Hic2	100	89.516	ENSECAG00000017997	HIC2	100	89.516	Equus_caballus
ENSMUSG00000050240	Hic2	96	57.416	ENSELUG00000021193	hic2	100	57.576	Esox_lucius
ENSMUSG00000050240	Hic2	96	45.705	ENSELUG00000002408	hic2	100	46.916	Esox_lucius
ENSMUSG00000050240	Hic2	100	87.258	ENSFCAG00000023903	HIC2	100	87.258	Felis_catus
ENSMUSG00000050240	Hic2	96	64.803	ENSFALG00000014495	HIC2	100	65.846	Ficedula_albicollis
ENSMUSG00000050240	Hic2	100	86.613	ENSFDAG00000011245	HIC2	100	86.613	Fukomys_damarensis
ENSMUSG00000050240	Hic2	96	55.810	ENSFHEG00000006964	hic2	100	56.607	Fundulus_heteroclitus
ENSMUSG00000050240	Hic2	99	54.348	ENSGMOG00000011705	hic2	99	54.644	Gadus_morhua
ENSMUSG00000050240	Hic2	96	65.517	ENSGALG00000033416	HIC2	100	64.860	Gallus_gallus
ENSMUSG00000050240	Hic2	96	56.352	ENSGAFG00000018031	hic2	100	56.888	Gambusia_affinis
ENSMUSG00000050240	Hic2	99	54.844	ENSGACG00000004268	hic2	99	56.075	Gasterosteus_aculeatus
ENSMUSG00000050240	Hic2	96	65.512	ENSGAGG00000016023	HIC2	100	66.337	Gopherus_agassizii
ENSMUSG00000050240	Hic2	100	87.903	ENSGGOG00000037763	HIC2	100	88.226	Gorilla_gorilla
ENSMUSG00000050240	Hic2	96	55.610	ENSHBUG00000012959	hic2	100	56.796	Haplochromis_burtoni
ENSMUSG00000050240	Hic2	100	86.774	ENSHGLG00000008541	HIC2	100	86.774	Heterocephalus_glaber_female
ENSMUSG00000050240	Hic2	100	84.677	ENSHGLG00100000200	-	100	85.000	Heterocephalus_glaber_male
ENSMUSG00000050240	Hic2	100	77.903	ENSHGLG00100007585	-	100	78.226	Heterocephalus_glaber_male
ENSMUSG00000050240	Hic2	53	65.833	ENSIPUG00000003207	hic2	63	65.833	Ictalurus_punctatus
ENSMUSG00000050240	Hic2	96	57.050	ENSIPUG00000013986	hic2	100	56.888	Ictalurus_punctatus
ENSMUSG00000050240	Hic2	100	88.226	ENSSTOG00000006360	HIC2	100	88.226	Ictidomys_tridecemlineatus
ENSMUSG00000050240	Hic2	99	88.207	ENSJJAG00000009939	Hic2	100	87.722	Jaculus_jaculus
ENSMUSG00000050240	Hic2	90	47.448	ENSKMAG00000004641	hic2	91	48.141	Kryptolebias_marmoratus
ENSMUSG00000050240	Hic2	96	55.892	ENSLBEG00000024306	hic2	100	56.260	Labrus_bergylta
ENSMUSG00000050240	Hic2	52	67.797	ENSLBEG00000013821	hic2	66	67.797	Labrus_bergylta
ENSMUSG00000050240	Hic2	65	53.953	ENSLBEG00000010933	-	65	60.452	Labrus_bergylta
ENSMUSG00000050240	Hic2	95	53.986	ENSLACG00000011864	HIC2	95	54.891	Latimeria_chalumnae
ENSMUSG00000050240	Hic2	97	62.541	ENSLOCG00000002169	hic2	96	62.602	Lepisosteus_oculatus
ENSMUSG00000050240	Hic2	100	87.742	ENSMFAG00000004992	HIC2	100	88.065	Macaca_fascicularis
ENSMUSG00000050240	Hic2	99	87.480	ENSMMUG00000031089	HIC2	99	87.805	Macaca_mulatta
ENSMUSG00000050240	Hic2	100	87.419	ENSMNEG00000003509	HIC2	100	87.742	Macaca_nemestrina
ENSMUSG00000050240	Hic2	100	87.903	ENSMLEG00000031489	HIC2	100	88.226	Mandrillus_leucophaeus
ENSMUSG00000050240	Hic2	96	55.089	ENSMAMG00000013476	hic2	100	55.662	Mastacembelus_armatus
ENSMUSG00000050240	Hic2	99	54.589	ENSMZEG00005010459	hic2	99	55.836	Maylandia_zebra
ENSMUSG00000050240	Hic2	97	64.860	ENSMGAG00000000949	HIC2	100	64.590	Meleagris_gallopavo
ENSMUSG00000050240	Hic2	100	91.774	ENSMAUG00000019790	Hic2	100	91.290	Mesocricetus_auratus
ENSMUSG00000050240	Hic2	100	85.484	ENSMICG00000044556	HIC2	100	86.452	Microcebus_murinus
ENSMUSG00000050240	Hic2	100	93.226	ENSMOCG00000021488	Hic2	100	93.226	Microtus_ochrogaster
ENSMUSG00000050240	Hic2	97	70.048	ENSMODG00000017662	HIC2	98	69.887	Monodelphis_domestica
ENSMUSG00000050240	Hic2	96	56.757	ENSMALG00000021292	hic2	100	56.082	Monopterus_albus
ENSMUSG00000050240	Hic2	100	98.384	MGP_CAROLIEiJ_G0020510	Hic2	100	98.384	Mus_caroli
ENSMUSG00000050240	Hic2	100	98.869	MGP_PahariEiJ_G0016215	Hic2	100	98.869	Mus_pahari
ENSMUSG00000050240	Hic2	100	99.838	MGP_SPRETEiJ_G0021405	Hic2	100	99.838	Mus_spretus
ENSMUSG00000050240	Hic2	100	88.065	ENSMPUG00000003198	HIC2	100	88.065	Mustela_putorius_furo
ENSMUSG00000050240	Hic2	100	87.419	ENSMLUG00000009669	HIC2	100	87.419	Myotis_lucifugus
ENSMUSG00000050240	Hic2	100	90.982	ENSNGAG00000000850	Hic2	100	90.982	Nannospalax_galili
ENSMUSG00000050240	Hic2	96	55.935	ENSNBRG00000020589	hic2	100	57.120	Neolamprologus_brichardi
ENSMUSG00000050240	Hic2	99	78.150	ENSNLEG00000000203	HIC2	99	79.107	Nomascus_leucogenys
ENSMUSG00000050240	Hic2	100	86.591	ENSODEG00000016054	HIC2	100	86.753	Octodon_degus
ENSMUSG00000050240	Hic2	97	56.331	ENSONIG00000014335	hic2	100	57.512	Oreochromis_niloticus
ENSMUSG00000050240	Hic2	99	85.251	ENSOCUG00000010516	HIC2	92	85.251	Oryctolagus_cuniculus
ENSMUSG00000050240	Hic2	96	55.233	ENSORLG00000002131	hic2	100	56.656	Oryzias_latipes
ENSMUSG00000050240	Hic2	96	55.233	ENSORLG00020006527	hic2	100	56.656	Oryzias_latipes_hni
ENSMUSG00000050240	Hic2	96	55.395	ENSORLG00015016278	hic2	100	56.818	Oryzias_latipes_hsok
ENSMUSG00000050240	Hic2	96	54.911	ENSOMEG00000018752	hic2	100	56.331	Oryzias_melastigma
ENSMUSG00000050240	Hic2	100	86.774	ENSOGAG00000030274	HIC2	100	86.774	Otolemur_garnettii
ENSMUSG00000050240	Hic2	100	87.742	ENSPPAG00000037732	HIC2	100	88.065	Pan_paniscus
ENSMUSG00000050240	Hic2	100	86.495	ENSPPRG00000021035	-	100	86.495	Panthera_pardus
ENSMUSG00000050240	Hic2	99	87.317	ENSPTRG00000046730	HIC2	99	87.642	Pan_troglodytes
ENSMUSG00000050240	Hic2	100	88.226	ENSPANG00000024301	HIC2	100	88.226	Papio_anubis
ENSMUSG00000050240	Hic2	96	61.613	ENSPKIG00000002187	hic2	100	60.191	Paramormyrops_kingsleyae
ENSMUSG00000050240	Hic2	96	55.464	ENSPKIG00000017929	-	100	54.516	Paramormyrops_kingsleyae
ENSMUSG00000050240	Hic2	96	65.017	ENSPSIG00000000992	-	100	65.517	Pelodiscus_sinensis
ENSMUSG00000050240	Hic2	96	65.347	ENSPSIG00000000839	-	100	66.010	Pelodiscus_sinensis
ENSMUSG00000050240	Hic2	96	55.484	ENSPMGG00000013191	hic2	100	56.039	Periophthalmus_magnuspinnatus
ENSMUSG00000050240	Hic2	96	73.378	ENSPCIG00000026758	HIC2	100	73.877	Phascolarctos_cinereus
ENSMUSG00000050240	Hic2	97	56.423	ENSPFOG00000020465	hic2	100	56.958	Poecilia_formosa
ENSMUSG00000050240	Hic2	96	56.515	ENSPLAG00000014754	hic2	100	56.888	Poecilia_latipinna
ENSMUSG00000050240	Hic2	96	56.515	ENSPMEG00000020119	hic2	100	57.050	Poecilia_mexicana
ENSMUSG00000050240	Hic2	96	57.374	ENSPREG00000010443	hic2	100	57.792	Poecilia_reticulata
ENSMUSG00000050240	Hic2	100	87.581	ENSPPYG00000012022	HIC2	100	87.903	Pongo_abelii
ENSMUSG00000050240	Hic2	100	85.323	ENSPCAG00000015907	HIC2	100	85.645	Procavia_capensis
ENSMUSG00000050240	Hic2	100	86.290	ENSPCOG00000013219	HIC2	100	86.290	Propithecus_coquereli
ENSMUSG00000050240	Hic2	84	90.566	ENSPVAG00000000111	HIC2	84	90.566	Pteropus_vampyrus
ENSMUSG00000050240	Hic2	96	56.006	ENSPNYG00000007402	hic2	100	57.189	Pundamilia_nyererei
ENSMUSG00000050240	Hic2	97	42.645	ENSPNAG00000022553	hic1l	96	42.459	Pygocentrus_nattereri
ENSMUSG00000050240	Hic2	97	53.249	ENSPNAG00000002230	hic2	99	56.070	Pygocentrus_nattereri
ENSMUSG00000050240	Hic2	100	93.408	ENSRNOG00000051458	Hic2	100	93.569	Rattus_norvegicus
ENSMUSG00000050240	Hic2	100	83.736	ENSRBIG00000031113	HIC2	100	84.058	Rhinopithecus_bieti
ENSMUSG00000050240	Hic2	100	87.258	ENSRROG00000035179	HIC2	100	87.581	Rhinopithecus_roxellana
ENSMUSG00000050240	Hic2	100	87.581	ENSSBOG00000026991	HIC2	100	87.419	Saimiri_boliviensis_boliviensis
ENSMUSG00000050240	Hic2	96	52.692	ENSSFOG00015016070	-	100	52.419	Scleropages_formosus
ENSMUSG00000050240	Hic2	96	59.300	ENSSFOG00015015304	hic2	100	58.898	Scleropages_formosus
ENSMUSG00000050240	Hic2	96	56.704	ENSSMAG00000007076	hic2	100	57.649	Scophthalmus_maximus
ENSMUSG00000050240	Hic2	96	55.974	ENSSDUG00000022819	hic2	100	57.096	Seriola_dumerili
ENSMUSG00000050240	Hic2	96	55.821	ENSSLDG00000003123	hic2	100	56.916	Seriola_lalandi_dorsalis
ENSMUSG00000050240	Hic2	96	56.149	ENSSPAG00000008074	hic2	100	57.097	Stegastes_partitus
ENSMUSG00000050240	Hic2	100	81.481	ENSSSCG00000036472	HIC2	100	81.481	Sus_scrofa
ENSMUSG00000050240	Hic2	97	64.368	ENSTGUG00000008699	HIC2	100	65.410	Taeniopygia_guttata
ENSMUSG00000050240	Hic2	96	52.077	ENSTRUG00000013139	hic2	100	53.774	Takifugu_rubripes
ENSMUSG00000050240	Hic2	83	61.624	ENSTNIG00000001094	hic2	92	61.993	Tetraodon_nigroviridis
ENSMUSG00000050240	Hic2	100	87.903	ENSUAMG00000010428	HIC2	100	87.903	Ursus_americanus
ENSMUSG00000050240	Hic2	78	94.815	ENSUMAG00000003594	HIC2	86	94.815	Ursus_maritimus
ENSMUSG00000050240	Hic2	100	88.387	ENSVVUG00000020688	HIC2	100	88.387	Vulpes_vulpes
ENSMUSG00000050240	Hic2	99	60.289	ENSXETG00000022419	hic2	97	60.096	Xenopus_tropicalis
ENSMUSG00000050240	Hic2	96	56.189	ENSXCOG00000001544	hic2	100	56.726	Xiphophorus_couchianus
ENSMUSG00000050240	Hic2	96	56.189	ENSXMAG00000020311	hic2	100	56.726	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0006974	cellular response to DNA damage stimulus	21873635.	IBA	Process
GO:0008022	protein C-terminus binding	-	ISO	Function
GO:0046872	metal ion binding	-	IEA	Function