EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000052397 (Gene tree)
Gene ID: 22350
Gene Symbol: Ezr
Alias: Vil2|cytovillin|ezrin|p81
Full Name: ezrin
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 44744
Position: chr17: 6738041-6782784
Accession: 98931
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
23912277	The RNA binding protein repertoire of embryonic stem cells	IC & mESC	2013 Aug 4	Kwon SC	DOI: 10.1038/nsmb.2638
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	RBDmap & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000131131	-	643	-	-	- (aa)	-	-
ENSMUST00000064234	-	3164	-	ENSMUSP00000063734	586 (aa)	-	P26040

Gene Model

Click here to download ENSMUSG00000052397's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04530	Tight junction	KEGG
mmu04670	Leukocyte transendothelial migration	KEGG
mmu04810	Regulation of actin cytoskeleton	KEGG
mmu04971	Gastric acid secretion	KEGG
mmu05205	Proteoglycans in cancer	KEGG
mmu05206	MicroRNAs in cancer	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000052397's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000052397	Ezr	100	96.587	ENSG00000092820	EZR	100	96.587	Homo_sapiens
ENSMUSG00000052397	Ezr	100	75.768	ENSG00000137710	RDX	100	84.314	Homo_sapiens
ENSMUSG00000052397	Ezr	100	72.572	ENSG00000147065	MSN	100	85.437	Homo_sapiens
ENSMUSG00000052397	Ezr	100	75.939	ENSMUSG00000032050	Rdx	93	83.196	Mus_musculus
ENSMUSG00000052397	Ezr	100	72.449	ENSMUSG00000031207	Msn	100	72.449	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	-	ISO	Process
GO:0001650	fibrillar center	-	ISO	Component
GO:0001726	ruffle	-	ISO	Component
GO:0001772	immunological synapse	-	ISO	Component
GO:0001772	immunological synapse	-	ISO	Component
GO:0001931	uropod	11728336.	IDA	Component
GO:0001951	intestinal D-glucose absorption	22114352.	IGI	Process
GO:0003376	sphingosine-1-phosphate receptor signaling pathway	-	ISO	Process
GO:0003779	actin binding	-	ISO	Function
GO:0005515	protein binding	9472040.12068294.18321067.21289089.24385580.	IPI	Function
GO:0005737	cytoplasm	-	ISO	Component
GO:0005768	endosome	-	ISO	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005856	cytoskeleton	-	IEA	Component
GO:0005884	actin filament	-	ISO	Component
GO:0005886	plasma membrane	21377456.24385580.	IDA	Component
GO:0005886	plasma membrane	-	ISO	Component
GO:0005902	microvillus	9472040.17138661.20551175.23284756.	IDA	Component
GO:0005902	microvillus	-	ISO	Component
GO:0005903	brush border	22114352.24284068.	IDA	Component
GO:0005925	focal adhesion	-	ISO	Component
GO:0008017	microtubule binding	-	ISO	Function
GO:0008022	protein C-terminus binding	18321067.	IDA	Function
GO:0008092	cytoskeletal protein binding	-	IEA	Function
GO:0008360	regulation of cell shape	-	ISO	Process
GO:0010628	positive regulation of gene expression	-	ISO	Process
GO:0010737	protein kinase A signaling	-	ISO	Process
GO:0015629	actin cytoskeleton	-	ISO	Component
GO:0016020	membrane	-	IEA	Component
GO:0016323	basolateral plasma membrane	-	ISO	Component
GO:0016324	apical plasma membrane	14625387.	IDA	Component
GO:0016324	apical plasma membrane	-	ISO	Component
GO:0019898	extrinsic component of membrane	-	ISO	Component
GO:0019904	protein domain specific binding	-	ISO	Function
GO:0030033	microvillus assembly	22114352.	IGI	Process
GO:0030175	filopodium	-	ISO	Component
GO:0030315	T-tubule	-	ISO	Component
GO:0030953	astral microtubule organization	-	ISO	Process
GO:0031528	microvillus membrane	-	ISO	Component
GO:0031532	actin cytoskeleton reorganization	-	ISO	Process
GO:0031623	receptor internalization	16365167.	IMP	Process
GO:0032532	regulation of microvillus length	22114352.	IGI	Process
GO:0032991	protein-containing complex	-	ISO	Component
GO:0034236	protein kinase A catalytic subunit binding	-	ISO	Function
GO:0034237	protein kinase A regulatory subunit binding	-	ISO	Function
GO:0034629	cellular protein-containing complex localization	-	ISO	Process
GO:0035088	establishment or maintenance of apical/basal cell polarity	15177033.	IMP	Process
GO:0036064	ciliary basal body	14996907.	IDA	Component
GO:0040018	positive regulation of multicellular organism growth	22114352.	IGI	Process
GO:0042802	identical protein binding	-	ISO	Function
GO:0042995	cell projection	-	ISO	Component
GO:0043209	myelin sheath	17634366.	HDA	Component
GO:0043622	cortical microtubule organization	-	ISO	Process
GO:0044297	cell body	-	ISO	Component
GO:0044393	microspike	-	ISO	Component
GO:0044548	S100 protein binding	-	ISO	Function
GO:0044853	plasma membrane raft	-	ISO	Component
GO:0044877	protein-containing complex binding	-	ISO	Function
GO:0045121	membrane raft	-	ISO	Component
GO:0045177	apical part of cell	9890997.14996907.	IDA	Component
GO:0045177	apical part of cell	-	ISO	Component
GO:0046847	filopodium assembly	-	ISO	Process
GO:0048015	phosphatidylinositol-mediated signaling	-	ISO	Process
GO:0048471	perinuclear region of cytoplasm	-	ISO	Component
GO:0050714	positive regulation of protein secretion	-	ISO	Process
GO:0050839	cell adhesion molecule binding	-	ISO	Function
GO:0050860	negative regulation of T cell receptor signaling pathway	-	ISO	Process
GO:0051015	actin filament binding	-	ISO	Function
GO:0051017	actin filament bundle assembly	-	ISO	Process
GO:0051018	protein kinase A binding	-	ISO	Function
GO:0051117	ATPase binding	-	ISO	Function
GO:0051286	cell tip	-	ISO	Component
GO:0051660	establishment of centrosome localization	-	ISO	Process
GO:0061028	establishment of endothelial barrier	-	ISO	Process
GO:0070373	negative regulation of ERK1 and ERK2 cascade	-	ISO	Process
GO:0071320	cellular response to cAMP	-	ISO	Process
GO:0071437	invadopodium	-	ISO	Component
GO:0071944	cell periphery	-	ISO	Component
GO:0072659	protein localization to plasma membrane	-	ISO	Process
GO:0072697	protein localization to cell cortex	-	ISO	Process
GO:0097449	astrocyte projection	-	ISO	Component
GO:0097454	Schwann cell microvillus	-	ISO	Component
GO:0097718	disordered domain specific binding	18321067.	IDA	Function
GO:0098592	cytoplasmic side of apical plasma membrane	-	ISO	Component
GO:1900041	negative regulation of interleukin-2 secretion	-	ISO	Process
GO:1902115	regulation of organelle assembly	-	ISO	Process
GO:1902896	terminal web assembly	22114352.	IGI	Process
GO:1902966	positive regulation of protein localization to early endosome	-	ISO	Process
GO:1903078	positive regulation of protein localization to plasma membrane	22114352.	IGI	Process
GO:1903364	positive regulation of cellular protein catabolic process	-	ISO	Process
GO:1903753	negative regulation of p38MAPK cascade	-	ISO	Process
GO:2000643	positive regulation of early endosome to late endosome transport	-	ISO	Process