EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000066551 (Gene tree)
Gene ID: 15289
Gene Symbol: Hmgb1
Alias: DEF|HMG-1|Hmg1|SBP-1|amphoterin|p30
Full Name: high mobility group box 1
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Minus strand
Length: 137788
Position: chr5: 149046702-149184489
Accession: 96113
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
25993413	Label-Free Protein RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression	IC & MEF	2015	Boucas J	DOI: 10.1371/journal.pone.0125745
27281784	Identification of RNA binding Proteins in Macrophages by Interactome Capture	IC & RAW264.7	2016 Jun 8	Liepelt A	DOI: 10.1074/mcp.M115.056564
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	IC & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000139443	-	923	-	ENSMUSP00000144129	171 (aa)	-	A0A0J9YUD8
ENSMUST00000123645	-	461	-	-	- (aa)	-	-
ENSMUST00000093196	-	1092	-	ENSMUSP00000106131	215 (aa)	XP_003945388	P63158
ENSMUST00000138553	-	428	-	ENSMUSP00000118733	124 (aa)	-	D3YZ18
ENSMUST00000155086	-	902	-	-	- (aa)	-	-
ENSMUST00000125605	-	604	-	ENSMUSP00000114515	92 (aa)	-	D3YVC6
ENSMUST00000133667	-	654	-	-	- (aa)	-	-
ENSMUST00000085546	-	2838	-	ENSMUSP00000082682	215 (aa)	XP_003945388	P63158
ENSMUST00000202133	-	685	-	ENSMUSP00000144412	211 (aa)	-	A0A0J9YUZ4
ENSMUST00000110505	-	1720	-	ENSMUSP00000106132	215 (aa)	XP_003945388	P63158

Gene Model

Click here to download ENSMUSG00000066551's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu03410	Base excision repair	KEGG
mmu04140	Autophagy - animal	KEGG
mmu04217	Necroptosis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000066551's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000066551	Hmgb1	100	100.000	ENSG00000189403	HMGB1	100	99.367	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000401	open form four-way junction DNA binding	-	ISO	Function
GO:0000402	crossed form four-way junction DNA binding	-	ISO	Function
GO:0000790	nuclear chromatin	21873635.	IBA	Component
GO:0001654	eye development	10391216.	IMP	Process
GO:0001773	myeloid dendritic cell activation	19890330.	IMP	Process
GO:0001786	phosphatidylserine binding	20826760.	TAS	Function
GO:0001934	positive regulation of protein phosphorylation	7741753.	IDA	Process
GO:0001935	endothelial cell proliferation	16365390.	IDA	Process
GO:0002053	positive regulation of mesenchymal cell proliferation	-	ISO	Process
GO:0002218	activation of innate immune response	21873635.	IBA	Process
GO:0002270	plasmacytoid dendritic cell activation	19890330.	IMP	Process
GO:0002281	macrophage activation involved in immune response	19890330.	IMP	Process
GO:0002643	regulation of tolerance induction	18631454.	IMP	Process
GO:0002840	regulation of T cell mediated immune response to tumor cell	23108142.	IDA	Process
GO:0003681	bent DNA binding	-	ISO	Function
GO:0003690	double-stranded DNA binding	19890330.	IDA	Function
GO:0003725	double-stranded RNA binding	19890330.	IDA	Function
GO:0003727	single-stranded RNA binding	19890330.	IDA	Function
GO:0005125	cytokine activity	7635200.7741753.	IDA	Function
GO:0005125	cytokine activity	-	ISO	Function
GO:0005515	protein binding	11099378.19264983.20819940.22842346.	IPI	Function
GO:0005576	extracellular region	20826760.	TAS	Component
GO:0005615	extracellular space	7635200.12609598.15140875.28096568.	IDA	Component
GO:0005634	nucleus	9767109.12609598.14744997.28096568.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	9767109.12609598.	IDA	Component
GO:0005769	early endosome	19890330.	IDA	Component
GO:0006284	base-excision repair	17803946.	IMP	Process
GO:0006310	DNA recombination	21873635.	IBA	Process
GO:0006338	chromatin remodeling	21873635.	IBA	Process
GO:0006357	regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0006954	inflammatory response	20826760.	TAS	Process
GO:0008134	transcription factor binding	21873635.	IBA	Function
GO:0008301	DNA binding, bending	21873635.	IBA	Function
GO:0010469	regulation of signaling receptor activity	21873635.	IBA	Process
GO:0010506	regulation of autophagy	20819940.	IMP	Process
GO:0010508	positive regulation of autophagy	21873635.	IBA	Process
GO:0010858	calcium-dependent protein kinase regulator activity	7741753.	IDA	Function
GO:0030295	protein kinase activator activity	7741753.	IDA	Function
GO:0030324	lung development	10391216.	IMP	Process
GO:0030335	positive regulation of cell migration	-	ISO	Process
GO:0031497	chromatin assembly	18650382.	IDA	Process
GO:0032392	DNA geometric change	-	ISO	Process
GO:0032502	developmental process	21873635.	IBA	Process
GO:0032727	positive regulation of interferon-alpha production	19890330.	IMP	Process
GO:0032728	positive regulation of interferon-beta production	19890330.	IMP	Process
GO:0032755	positive regulation of interleukin-6 production	21873635.	IBA	Process
GO:0032755	positive regulation of interleukin-6 production	19264983.19890330.	IMP	Process
GO:0032760	positive regulation of tumor necrosis factor production	21873635.	IBA	Process
GO:0032760	positive regulation of tumor necrosis factor production	19264983.19890330.	IMP	Process
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	16267105.	IDA	Process
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	16267105.	IDA	Process
GO:0035767	endothelial cell chemotaxis	16365390.	IDA	Process
GO:0043005	neuron projection	12609598.	IDA	Component
GO:0045089	positive regulation of innate immune response	21873635.	IBA	Process
GO:0045089	positive regulation of innate immune response	19890330.	IMP	Process
GO:0045639	positive regulation of myeloid cell differentiation	7635200.7741753.	IDA	Process
GO:0045819	positive regulation of glycogen catabolic process	10391216.	IMP	Process
GO:0045931	positive regulation of mitotic cell cycle	-	ISO	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	10391216.	IMP	Process
GO:0050716	positive regulation of interleukin-1 secretion	21873635.	IBA	Process
GO:0050718	positive regulation of interleukin-1 beta secretion	21873635.	IBA	Process
GO:0050718	positive regulation of interleukin-1 beta secretion	19890330.	IMP	Process
GO:0050930	induction of positive chemotaxis	-	ISO	Process
GO:0051384	response to glucocorticoid	10391216.	IMP	Process
GO:0060326	cell chemotaxis	21873635.	IBA	Process
GO:0070374	positive regulation of ERK1 and ERK2 cascade	21873635.	IBA	Process
GO:0070374	positive regulation of ERK1 and ERK2 cascade	16365390.	IDA	Process
GO:0071222	cellular response to lipopolysaccharide	28096568.	IDA	Process
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	19264983.	IMP	Process
GO:0090303	positive regulation of wound healing	16365390.	IDA	Process
GO:0098761	cellular response to interleukin-7	29581031.	IDA	Process
GO:1901224	positive regulation of NIK/NF-kappaB signaling	21873635.	IBA	Process
GO:1901224	positive regulation of NIK/NF-kappaB signaling	16267105.	IDA	Process
GO:1902741	positive regulation of interferon-alpha secretion	21873635.	IBA	Process
GO:1903672	positive regulation of sprouting angiogenesis	16365390.	IDA	Process
GO:2000819	regulation of nucleotide-excision repair	18650382.	IMP	Process