EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSMUSG00000068036 (Gene tree)
Gene ID: 17356
Gene Symbol: Afdn
Alias: 5033403D15Rik|AF6|Afadin|I-afadin|Mllt4|S-afadin
Full Name: afadin%2C adherens junction formation factor
Gene Type: protein_coding
Species: Mus_musculus
Status: putative
Strand: Plus strand
Length: 145612
Position: chr17: 13760539-13906150
Accession: 1314653
RBP type: non-canonical RBP
Summary: -

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27768875	High Resolution Mapping of RNA Binding Regions in the Nuclear Proteome of Embryonic Stem Cells	nIC & mESC	2016.09	He C	DOI: 10.1016/j.molcel.2016.09.034
27452465	The Cardiomyocyte RNA Binding Proteome: Links to Intermediary Metabolism and Heart Disease	RBDmap & HL_1	2016 Jul 21	Liao Y	DOI: 10.1016/j.celrep.2016.06.084

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSMUST00000156591	-	798	-	ENSMUSP00000122204	221 (aa)	-	D3Z7L2
ENSMUST00000137495	-	3246	-	-	- (aa)	-	-
ENSMUST00000124922	-	2662	-	-	- (aa)	-	-
ENSMUST00000141640	-	779	-	-	- (aa)	-	-
ENSMUST00000137784	-	5684	XM_006523752	ENSMUSP00000119153	1827 (aa)	XP_006523815	E9Q9C3
ENSMUST00000137708	-	5153	-	ENSMUSP00000114485	1663 (aa)	-	E9PYX7
ENSMUST00000133422	-	1167	-	-	- (aa)	-	-
ENSMUST00000150848	-	5418	XM_006523762	ENSMUSP00000122447	1805 (aa)	XP_006523825	Q9QZQ1
ENSMUST00000139347	-	822	-	ENSMUSP00000115250	229 (aa)	-	D3YUD2
ENSMUST00000124188	-	610	-	-	- (aa)	-	-
ENSMUST00000137503	-	593	-	-	- (aa)	-	-
ENSMUST00000123030	-	427	-	-	- (aa)	-	-
ENSMUST00000170827	-	7338	-	ENSMUSP00000128891	1805 (aa)	-	E9Q852
ENSMUST00000139666	-	7732	XM_006523757	ENSMUSP00000118318	1820 (aa)	XP_006523820	Q9QZQ1
ENSMUST00000137531	-	1210	-	ENSMUSP00000116711	380 (aa)	-	F7C3I9
ENSMUST00000136087	-	241	-	-	- (aa)	-	-

Gene Model

Click here to download ENSMUSG00000068036's gene model file

Pathways

Pathway ID	Pathway Name	Source
mmu04014	Ras signaling pathway	KEGG
mmu04015	Rap1 signaling pathway	KEGG
mmu04024	cAMP signaling pathway	KEGG
mmu04520	Adherens junction	KEGG
mmu04530	Tight junction	KEGG
mmu04670	Leukocyte transendothelial migration	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSMUSG00000068036's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSMUSG00000068036	Afdn	100	96.943	ENSG00000130396	AFDN	100	96.761	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	12446711.22027834.	IPI	Function
GO:0005654	nucleoplasm	-	ISO	Component
GO:0005737	cytoplasm	15509704.22027834.	IDA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0005886	plasma membrane	-	ISO	Component
GO:0005911	cell-cell junction	18604197.23990464.	IDA	Component
GO:0005912	adherens junction	12203721.12515806.	IDA	Component
GO:0005913	cell-cell adherens junction	21873635.	IBA	Component
GO:0005913	cell-cell adherens junction	11731229.15728677.	IDA	Component
GO:0005913	cell-cell adherens junction	-	ISO	Component
GO:0007155	cell adhesion	-	IEA	Process
GO:0007165	signal transduction	-	IEA	Process
GO:0010628	positive regulation of gene expression	-	ISO	Process
GO:0016607	nuclear speck	-	ISO	Component
GO:0017016	Ras GTPase binding	-	ISO	Function
GO:0021537	telencephalon development	25100583.	IGI	Process
GO:0021987	cerebral cortex development	25100583.	IGI	Process
GO:0021987	cerebral cortex development	25100583.	IMP	Process
GO:0022409	positive regulation of cell-cell adhesion	-	ISO	Process
GO:0030054	cell junction	15509704.	IDA	Component
GO:0030054	cell junction	-	ISO	Component
GO:0030274	LIM domain binding	-	ISO	Function
GO:0030336	negative regulation of cell migration	-	ISO	Process
GO:0030424	axon	-	ISO	Component
GO:0032880	regulation of protein localization	21873635.	IBA	Process
GO:0034334	adherens junction maintenance	25100583.	IMP	Process
GO:0036477	somatodendritic compartment	-	ISO	Component
GO:0043296	apical junction complex	22512338.	IDA	Component
GO:0043547	positive regulation of GTPase activity	-	ISO	Process
GO:0044291	cell-cell contact zone	-	ISO	Component
GO:0044331	cell-cell adhesion mediated by cadherin	23990464.	IMP	Process
GO:0045177	apical part of cell	10704870.	IDA	Component
GO:0048854	brain morphogenesis	25100583.	IGI	Process
GO:0048872	homeostasis of number of cells	25100583.	IGI	Process
GO:0050775	positive regulation of dendrite morphogenesis	-	ISO	Process
GO:0050839	cell adhesion molecule binding	21873635.	IBA	Function
GO:0050839	cell adhesion molecule binding	10225955.	IPI	Function
GO:0051015	actin filament binding	-	ISO	Function
GO:0060019	radial glial cell differentiation	25100583.	IGI	Process
GO:0060076	excitatory synapse	-	ISO	Component
GO:0060563	neuroepithelial cell differentiation	25100583.	IGI	Process
GO:0061003	positive regulation of dendritic spine morphogenesis	-	ISO	Process
GO:0061885	positive regulation of mini excitatory postsynaptic potential	-	ISO	Process
GO:0061951	establishment of protein localization to plasma membrane	23990464.	IMP	Process
GO:0070160	tight junction	-	ISO	Component
GO:0070445	regulation of oligodendrocyte progenitor proliferation	25100583.	IGI	Process
GO:0070830	bicellular tight junction assembly	-	ISO	Process
GO:0090557	establishment of endothelial intestinal barrier	-	ISO	Process
GO:0140059	dendrite arborization	-	ISO	Process
GO:1902414	protein localization to cell junction	22512338.	IMP	Process
GO:1903861	positive regulation of dendrite extension	-	ISO	Process
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	-	ISO	Process