EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSRNOG00000003041 (Gene tree)
Gene ID: 287522
Gene Symbol: Smg6
Alias: LOC287522|LOC303309|LRRGT00040|RGD1309609
Full Name: SMG6 nonsense mediated mRNA decay factor
Gene Type: protein_coding
Species: Rattus_norvegicus
Status: putative
Strand: Plus strand
Length: 234582 bases
Position: chr10:61772449-62007030
Accession: 1595918
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSRNOP00000004058	EST1	PF10374.9	1.8e-13	1	1
ENSRNOP00000004058	EST1_DNA_bind	PF10373.9	7.9e-61	1	1
ENSRNOP00000004058	PIN_4	PF13638.6	2.2e-22	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSRNOT00000092241	-	3086	-	ENSRNOP00000075895	356 (aa)	-	A0A0U1RS16
ENSRNOT00000004058	-	5805	-	ENSRNOP00000004058	1418 (aa)	-	D4A589
ENSRNOT00000052412	-	498	-	-	- (aa)	-	-

Gene Model

Click here to download ENSRNOG00000003041's gene model file

Pathways

Pathway ID	Pathway Name	Source
rno03015	mRNA surveillance pathway	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSRNOG00000003041's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSRNOG00000003041	Smg6	100	91.332	ENSG00000070366	SMG6	100	97.456	Homo_sapiens
ENSRNOG00000003041	Smg6	94	68.035	ENSAPOG00000019448	smg6	74	54.788	Acanthochromis_polyacanthus
ENSRNOG00000003041	Smg6	100	91.614	ENSAMEG00000007632	SMG6	100	91.614	Ailuropoda_melanoleuca
ENSRNOG00000003041	Smg6	96	65.070	ENSACIG00000012997	smg6	98	49.308	Amphilophus_citrinellus
ENSRNOG00000003041	Smg6	96	66.197	ENSAOCG00000002630	smg6	74	54.496	Amphiprion_ocellaris
ENSRNOG00000003041	Smg6	97	65.027	ENSAPEG00000019101	smg6	74	54.574	Amphiprion_percula
ENSRNOG00000003041	Smg6	97	63.315	ENSATEG00000006483	smg6	73	54.096	Anabas_testudineus
ENSRNOG00000003041	Smg6	97	71.229	ENSACAG00000011783	SMG6	99	57.928	Anolis_carolinensis
ENSRNOG00000003041	Smg6	100	91.261	ENSANAG00000035760	SMG6	100	91.261	Aotus_nancymaae
ENSRNOG00000003041	Smg6	96	65.915	ENSACLG00000005288	smg6	82	53.550	Astatotilapia_calliptera
ENSRNOG00000003041	Smg6	97	65.429	ENSAMXG00000017326	smg6	99	50.069	Astyanax_mexicanus
ENSRNOG00000003041	Smg6	97	96.254	ENSBTAG00000000267	SMG6	100	91.614	Bos_taurus
ENSRNOG00000003041	Smg6	96	95.894	ENSCJAG00000001820	SMG6	100	91.473	Callithrix_jacchus
ENSRNOG00000003041	Smg6	100	91.121	ENSCAFG00000019260	SMG6	100	91.121	Canis_familiaris
ENSRNOG00000003041	Smg6	100	91.121	ENSCAFG00020009770	SMG6	100	91.121	Canis_lupus_dingo
ENSRNOG00000003041	Smg6	97	96.254	ENSCHIG00000021998	SMG6	100	91.473	Capra_hircus
ENSRNOG00000003041	Smg6	100	91.332	ENSTSYG00000003406	SMG6	100	97.456	Carlito_syrichta
ENSRNOG00000003041	Smg6	98	76.403	ENSCAPG00000016197	SMG6	99	82.670	Cavia_aperea
ENSRNOG00000003041	Smg6	100	90.493	ENSCPOG00000014878	SMG6	100	90.493	Cavia_porcellus
ENSRNOG00000003041	Smg6	100	91.473	ENSCCAG00000035801	SMG6	100	91.473	Cebus_capucinus
ENSRNOG00000003041	Smg6	100	91.614	ENSCATG00000031956	SMG6	100	91.614	Cercocebus_atys
ENSRNOG00000003041	Smg6	100	91.896	ENSCLAG00000006748	SMG6	100	91.896	Chinchilla_lanigera
ENSRNOG00000003041	Smg6	100	91.966	ENSCSAG00000013800	SMG6	100	91.966	Chlorocebus_sabaeus
ENSRNOG00000003041	Smg6	57	98.507	ENSCHOG00000005024	-	73	98.507	Choloepus_hoffmanni
ENSRNOG00000003041	Smg6	97	82.709	ENSCPBG00000020369	SMG6	100	71.766	Chrysemys_picta_bellii
ENSRNOG00000003041	Smg6	96	95.308	ENSCANG00000031764	SMG6	100	97.065	Colobus_angolensis_palliatus
ENSRNOG00000003041	Smg6	67	98.745	ENSCGRG00001019595	Smg6	100	94.087	Cricetulus_griseus_chok1gshd
ENSRNOG00000003041	Smg6	97	94.236	ENSCGRG00000007782	Smg6	100	89.041	Cricetulus_griseus_crigri
ENSRNOG00000003041	Smg6	96	63.202	ENSCSEG00000012757	smg6	93	51.696	Cynoglossus_semilaevis
ENSRNOG00000003041	Smg6	87	67.937	ENSCVAG00000012789	smg6	86	53.125	Cyprinodon_variegatus
ENSRNOG00000003041	Smg6	92	68.182	ENSDARG00000100481	smg6	100	50.606	Danio_rerio
ENSRNOG00000003041	Smg6	100	90.909	ENSDNOG00000048283	SMG6	100	90.909	Dasypus_novemcinctus
ENSRNOG00000003041	Smg6	100	89.404	ENSDORG00000016614	Smg6	94	96.847	Dipodomys_ordii
ENSRNOG00000003041	Smg6	93	100.000	ENSETEG00000016790	SMG6	93	100.000	Echinops_telfairi
ENSRNOG00000003041	Smg6	97	50.430	ENSEBUG00000005059	smg6	71	49.709	Eptatretus_burgeri
ENSRNOG00000003041	Smg6	96	95.601	ENSEASG00005009318	SMG6	99	91.955	Equus_asinus_asinus
ENSRNOG00000003041	Smg6	96	95.308	ENSECAG00000006519	SMG6	99	91.884	Equus_caballus
ENSRNOG00000003041	Smg6	100	80.973	ENSEEUG00000003493	SMG6	100	80.973	Erinaceus_europaeus
ENSRNOG00000003041	Smg6	91	68.997	ENSELUG00000005934	smg6	70	54.491	Esox_lucius
ENSRNOG00000003041	Smg6	100	92.248	ENSFCAG00000028817	SMG6	100	92.248	Felis_catus
ENSRNOG00000003041	Smg6	97	81.556	ENSFALG00000006538	SMG6	100	71.154	Ficedula_albicollis
ENSRNOG00000003041	Smg6	97	96.830	ENSFDAG00000015106	SMG6	100	91.614	Fukomys_damarensis
ENSRNOG00000003041	Smg6	87	68.571	ENSFHEG00000013282	smg6	74	53.313	Fundulus_heteroclitus
ENSRNOG00000003041	Smg6	60	68.224	ENSGMOG00000019077	smg6	58	68.224	Gadus_morhua
ENSRNOG00000003041	Smg6	97	80.980	ENSGALG00000003108	SMG6	98	71.339	Gallus_gallus
ENSRNOG00000003041	Smg6	87	69.524	ENSGAFG00000000379	smg6	74	53.569	Gambusia_affinis
ENSRNOG00000003041	Smg6	97	64.286	ENSGACG00000020521	smg6	100	52.850	Gasterosteus_aculeatus
ENSRNOG00000003041	Smg6	97	82.133	ENSGAGG00000025617	SMG6	100	71.673	Gopherus_agassizii
ENSRNOG00000003041	Smg6	100	91.896	ENSGGOG00000017156	SMG6	100	91.896	Gorilla_gorilla
ENSRNOG00000003041	Smg6	97	64.754	ENSHBUG00000021311	smg6	76	53.701	Haplochromis_burtoni
ENSRNOG00000003041	Smg6	100	90.992	ENSHGLG00000012882	SMG6	100	90.992	Heterocephalus_glaber_female
ENSRNOG00000003041	Smg6	100	90.992	ENSHGLG00100017815	SMG6	100	90.992	Heterocephalus_glaber_male
ENSRNOG00000003041	Smg6	90	64.815	ENSHCOG00000008761	smg6	83	58.151	Hippocampus_comes
ENSRNOG00000003041	Smg6	97	66.667	ENSIPUG00000012493	smg6	75	54.438	Ictalurus_punctatus
ENSRNOG00000003041	Smg6	97	97.406	ENSSTOG00000028127	SMG6	100	93.164	Ictidomys_tridecemlineatus
ENSRNOG00000003041	Smg6	97	97.695	ENSJJAG00000015367	Smg6	95	88.562	Jaculus_jaculus
ENSRNOG00000003041	Smg6	97	64.402	ENSKMAG00000000279	smg6	81	52.145	Kryptolebias_marmoratus
ENSRNOG00000003041	Smg6	96	65.915	ENSLBEG00000002184	smg6	78	51.429	Labrus_bergylta
ENSRNOG00000003041	Smg6	77	83.212	ENSLACG00000000806	-	98	59.506	Latimeria_chalumnae
ENSRNOG00000003041	Smg6	97	68.391	ENSLOCG00000006448	smg6	99	54.351	Lepisosteus_oculatus
ENSRNOG00000003041	Smg6	100	90.557	ENSLAFG00000001261	SMG6	100	90.557	Loxodonta_africana
ENSRNOG00000003041	Smg6	100	91.825	ENSMFAG00000003394	SMG6	100	91.825	Macaca_fascicularis
ENSRNOG00000003041	Smg6	100	91.755	ENSMMUG00000023161	SMG6	100	91.755	Macaca_mulatta
ENSRNOG00000003041	Smg6	100	86.990	ENSMNEG00000044592	SMG6	100	86.990	Macaca_nemestrina
ENSRNOG00000003041	Smg6	93	97.180	ENSMLEG00000029353	SMG6	100	97.180	Mandrillus_leucophaeus
ENSRNOG00000003041	Smg6	96	66.761	ENSMAMG00000020119	smg6	79	55.329	Mastacembelus_armatus
ENSRNOG00000003041	Smg6	97	64.754	ENSMZEG00005024736	smg6	76	53.765	Maylandia_zebra
ENSRNOG00000003041	Smg6	97	81.268	ENSMGAG00000005401	-	99	65.090	Meleagris_gallopavo
ENSRNOG00000003041	Smg6	97	96.542	ENSMICG00000012913	SMG6	100	93.164	Microcebus_murinus
ENSRNOG00000003041	Smg6	96	64.306	ENSMMOG00000010883	smg6	100	47.842	Mola_mola
ENSRNOG00000003041	Smg6	97	90.490	ENSMODG00000010622	SMG6	100	85.443	Monodelphis_domestica
ENSRNOG00000003041	Smg6	97	66.033	ENSMALG00000001106	smg6	73	54.834	Monopterus_albus
ENSRNOG00000003041	Smg6	100	97.179	MGP_CAROLIEiJ_G0016729	Smg6	100	97.465	Mus_caroli
ENSRNOG00000003041	Smg6	99	98.592	ENSMUSG00000038290	Smg6	99	98.592	Mus_musculus
ENSRNOG00000003041	Smg6	100	97.038	MGP_PahariEiJ_G0017866	Smg6	100	98.028	Mus_pahari
ENSRNOG00000003041	Smg6	100	97.461	MGP_SPRETEiJ_G0017572	Smg6	100	98.310	Mus_spretus
ENSRNOG00000003041	Smg6	97	95.389	ENSMPUG00000013046	SMG6	100	91.402	Mustela_putorius_furo
ENSRNOG00000003041	Smg6	100	90.980	ENSMLUG00000005739	SMG6	100	90.980	Myotis_lucifugus
ENSRNOG00000003041	Smg6	97	97.406	ENSNGAG00000007287	Smg6	100	92.729	Nannospalax_galili
ENSRNOG00000003041	Smg6	97	64.754	ENSNBRG00000009511	smg6	83	53.061	Neolamprologus_brichardi
ENSRNOG00000003041	Smg6	96	94.721	ENSNLEG00000017171	SMG6	100	97.260	Nomascus_leucogenys
ENSRNOG00000003041	Smg6	95	85.799	ENSMEUG00000015804	SMG6	100	82.112	Notamacropus_eugenii
ENSRNOG00000003041	Smg6	73	85.556	ENSOPRG00000000579	SMG6	83	98.421	Ochotona_princeps
ENSRNOG00000003041	Smg6	100	85.222	ENSODEG00000008038	SMG6	100	85.222	Octodon_degus
ENSRNOG00000003041	Smg6	97	65.041	ENSONIG00000005594	smg6	100	51.231	Oreochromis_niloticus
ENSRNOG00000003041	Smg6	97	87.608	ENSOANG00000021103	-	100	86.504	Ornithorhynchus_anatinus
ENSRNOG00000003041	Smg6	100	91.907	ENSOCUG00000013018	SMG6	100	92.048	Oryctolagus_cuniculus
ENSRNOG00000003041	Smg6	95	65.029	ENSORLG00000003317	smg6	78	52.438	Oryzias_latipes
ENSRNOG00000003041	Smg6	95	65.029	ENSORLG00020015343	smg6	78	52.256	Oryzias_latipes_hni
ENSRNOG00000003041	Smg6	95	65.318	ENSORLG00015020454	smg6	78	52.438	Oryzias_latipes_hsok
ENSRNOG00000003041	Smg6	97	63.610	ENSOMEG00000010838	smg6	79	51.696	Oryzias_melastigma
ENSRNOG00000003041	Smg6	97	96.254	ENSOGAG00000004483	SMG6	100	92.465	Otolemur_garnettii
ENSRNOG00000003041	Smg6	97	96.254	ENSOARG00000015076	SMG6	100	91.264	Ovis_aries
ENSRNOG00000003041	Smg6	100	91.825	ENSPPAG00000043296	SMG6	100	91.825	Pan_paniscus
ENSRNOG00000003041	Smg6	100	92.319	ENSPPRG00000014581	SMG6	100	92.319	Panthera_pardus
ENSRNOG00000003041	Smg6	95	95.575	ENSPTIG00000008925	SMG6	100	97.847	Panthera_tigris_altaica
ENSRNOG00000003041	Smg6	100	91.825	ENSPTRG00000008544	SMG6	100	97.456	Pan_troglodytes
ENSRNOG00000003041	Smg6	96	95.894	ENSPANG00000024588	SMG6	100	91.825	Papio_anubis
ENSRNOG00000003041	Smg6	97	81.844	ENSPSIG00000006660	SMG6	96	69.327	Pelodiscus_sinensis
ENSRNOG00000003041	Smg6	97	63.043	ENSPMGG00000000844	smg6	100	60.102	Periophthalmus_magnuspinnatus
ENSRNOG00000003041	Smg6	100	95.769	ENSPEMG00000020707	Smg6	100	95.769	Peromyscus_maniculatus_bairdii
ENSRNOG00000003041	Smg6	87	69.841	ENSPFOG00000012035	smg6	100	50.468	Poecilia_formosa
ENSRNOG00000003041	Smg6	87	69.524	ENSPLAG00000017660	smg6	74	53.465	Poecilia_latipinna
ENSRNOG00000003041	Smg6	87	69.841	ENSPMEG00000000258	smg6	74	53.743	Poecilia_mexicana
ENSRNOG00000003041	Smg6	87	69.841	ENSPREG00000010066	smg6	74	53.768	Poecilia_reticulata
ENSRNOG00000003041	Smg6	100	86.498	ENSPPYG00000007790	SMG6	100	86.498	Pongo_abelii
ENSRNOG00000003041	Smg6	96	92.375	ENSPCAG00000000552	SMG6	100	86.328	Procavia_capensis
ENSRNOG00000003041	Smg6	97	96.830	ENSPCOG00000020925	SMG6	100	92.671	Propithecus_coquereli
ENSRNOG00000003041	Smg6	86	100.000	ENSPVAG00000002159	SMG6	86	100.000	Pteropus_vampyrus
ENSRNOG00000003041	Smg6	97	64.754	ENSPNYG00000024151	smg6	81	55.400	Pundamilia_nyererei
ENSRNOG00000003041	Smg6	82	63.441	ENSPNAG00000015480	smg6	76	63.243	Pygocentrus_nattereri
ENSRNOG00000003041	Smg6	96	95.894	ENSRBIG00000024746	SMG6	100	91.825	Rhinopithecus_bieti
ENSRNOG00000003041	Smg6	100	91.896	ENSRROG00000030423	SMG6	100	96.673	Rhinopithecus_roxellana
ENSRNOG00000003041	Smg6	100	91.402	ENSSBOG00000022518	SMG6	100	89.782	Saimiri_boliviensis_boliviensis
ENSRNOG00000003041	Smg6	97	90.202	ENSSHAG00000010045	SMG6	98	85.151	Sarcophilus_harrisii
ENSRNOG00000003041	Smg6	97	66.856	ENSSFOG00015005436	smg6	70	56.593	Scleropages_formosus
ENSRNOG00000003041	Smg6	97	65.301	ENSSMAG00000019777	smg6	73	54.225	Scophthalmus_maximus
ENSRNOG00000003041	Smg6	97	65.217	ENSSDUG00000016412	smg6	74	54.257	Seriola_dumerili
ENSRNOG00000003041	Smg6	97	65.217	ENSSLDG00000020747	smg6	82	51.168	Seriola_lalandi_dorsalis
ENSRNOG00000003041	Smg6	97	78.386	ENSSPUG00000007152	SMG6	99	69.386	Sphenodon_punctatus
ENSRNOG00000003041	Smg6	97	64.208	ENSSPAG00000015633	smg6	74	54.438	Stegastes_partitus
ENSRNOG00000003041	Smg6	100	91.402	ENSSSCG00000017826	SMG6	100	91.402	Sus_scrofa
ENSRNOG00000003041	Smg6	97	80.403	ENSTGUG00000005836	SMG6	100	71.208	Taeniopygia_guttata
ENSRNOG00000003041	Smg6	97	63.660	ENSTRUG00000000358	smg6	100	48.069	Takifugu_rubripes
ENSRNOG00000003041	Smg6	92	68.675	ENSTNIG00000016164	smg6	100	49.501	Tetraodon_nigroviridis
ENSRNOG00000003041	Smg6	96	92.669	ENSTBEG00000011424	SMG6	100	87.094	Tupaia_belangeri
ENSRNOG00000003041	Smg6	91	91.667	ENSTTRG00000001175	SMG6	91	91.667	Tursiops_truncatus
ENSRNOG00000003041	Smg6	100	91.842	ENSUAMG00000025152	SMG6	100	91.282	Ursus_americanus
ENSRNOG00000003041	Smg6	95	96.142	ENSUMAG00000009306	SMG6	100	92.058	Ursus_maritimus
ENSRNOG00000003041	Smg6	85	92.593	ENSVPAG00000000225	SMG6	88	92.593	Vicugna_pacos
ENSRNOG00000003041	Smg6	100	90.909	ENSVVUG00000021727	SMG6	100	90.909	Vulpes_vulpes
ENSRNOG00000003041	Smg6	97	68.588	ENSXETG00000023799	SMG6	100	59.171	Xenopus_tropicalis
ENSRNOG00000003041	Smg6	97	62.881	ENSXCOG00000009867	smg6	74	54.140	Xiphophorus_couchianus
ENSRNOG00000003041	Smg6	97	63.115	ENSXMAG00000010321	smg6	86	53.961	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	21873635.	IBA	Process
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	-	ISO	Process
GO:0003723	RNA binding	-	ISO	Function
GO:0004521	endoribonuclease activity	21873635.	IBA	Function
GO:0004521	endoribonuclease activity	-	ISO	Function
GO:0005634	nucleus	-	ISO	Component
GO:0005697	telomerase holoenzyme complex	21873635.	IBA	Component
GO:0005730	nucleolus	-	IEA	Component
GO:0005730	nucleolus	-	ISO	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005829	cytosol	-	IEA	Component
GO:0005829	cytosol	-	ISO	Component
GO:0007004	telomere maintenance via telomerase	21873635.	IBA	Process
GO:0032204	regulation of telomere maintenance	-	ISO	Process
GO:0032210	regulation of telomere maintenance via telomerase	21873635.	IBA	Process
GO:0035145	exon-exon junction complex	-	IEA	Component
GO:0035145	exon-exon junction complex	-	ISO	Component
GO:0042162	telomeric DNA binding	21873635.	IBA	Function
GO:0042162	telomeric DNA binding	-	ISO	Function
GO:0043021	ribonucleoprotein complex binding	21873635.	IBA	Function
GO:0043021	ribonucleoprotein complex binding	-	ISO	Function
GO:0043487	regulation of RNA stability	21873635.	IBA	Process
GO:0070034	telomerase RNA binding	21873635.	IBA	Function
GO:0070034	telomerase RNA binding	-	ISO	Function
GO:0070182	DNA polymerase binding	-	IEA	Function
GO:0070182	DNA polymerase binding	-	ISO	Function
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	-	IEA	Process
GO:1904354	negative regulation of telomere capping	-	IEA	Process
GO:1904354	negative regulation of telomere capping	-	ISO	Process