EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSRNOG00000003084 (Gene tree)
Gene ID: 25591
Gene Symbol: Parp1
Alias: ADPRT 1|ARTD1|Adprt|MGC93658|Parp-1
Full Name: poly (ADP-ribose) polymerase 1
Gene Type: protein_coding
Species: Rattus_norvegicus
Status: putative
Strand: Plus strand
Length: 32540 bases
Position: chr13:98857177-98889716
Accession: 2053
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSRNOP00000004232	PARP	PF00644.20	8.3e-73	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSRNOT00000004232	-	3886	-	ENSRNOP00000004232	1014 (aa)	-	P27008

Gene Model

Click here to download ENSRNOG00000003084's gene model file

Pathways

Pathway ID	Pathway Name	Source
rno03410	Base excision repair	KEGG
rno04064	NF-kappa B signaling pathway	KEGG
rno04210	Apoptosis	KEGG
rno04217	Necroptosis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSRNOG00000003084's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSRNOG00000003084	Parp1	51	33.824	ENSRNOG00000012865	Parp3	100	33.824
ENSRNOG00000003084	Parp1	51	39.925	ENSRNOG00000008892	Parp2	94	39.925

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSRNOG00000003084	Parp1	100	91.429	ENSG00000143799	PARP1	100	91.626	Homo_sapiens
ENSRNOG00000003084	Parp1	100	69.697	ENSAPOG00000006414	parp1	100	69.931	Acanthochromis_polyacanthus
ENSRNOG00000003084	Parp1	99	89.511	ENSAMEG00000014451	PARP1	100	89.715	Ailuropoda_melanoleuca
ENSRNOG00000003084	Parp1	100	69.676	ENSACIG00000005651	parp1	100	69.382	Amphilophus_citrinellus
ENSRNOG00000003084	Parp1	100	70.225	ENSAOCG00000021005	parp1	100	70.421	Amphiprion_ocellaris
ENSRNOG00000003084	Parp1	100	70.225	ENSAPEG00000004784	parp1	100	70.323	Amphiprion_percula
ENSRNOG00000003084	Parp1	99	69.223	ENSATEG00000010457	parp1	99	69.261	Anabas_testudineus
ENSRNOG00000003084	Parp1	87	78.685	ENSAPLG00000014039	PARP1	100	78.458	Anas_platyrhynchos
ENSRNOG00000003084	Parp1	100	75.665	ENSACAG00000006189	PARP1	100	75.468	Anolis_carolinensis
ENSRNOG00000003084	Parp1	100	91.724	ENSANAG00000032699	PARP1	100	91.921	Aotus_nancymaae
ENSRNOG00000003084	Parp1	100	71.330	ENSACLG00000015489	parp1	100	71.034	Astatotilapia_calliptera
ENSRNOG00000003084	Parp1	100	68.549	ENSAMXG00000006465	parp1	100	68.647	Astyanax_mexicanus
ENSRNOG00000003084	Parp1	100	87.426	ENSBTAG00000000837	PARP1	100	87.721	Bos_taurus
ENSRNOG00000003084	Parp1	83	44.223	WBGene00004049	parp-1	100	46.743	Caenorhabditis_elegans
ENSRNOG00000003084	Parp1	100	91.429	ENSCJAG00000012831	PARP1	100	91.626	Callithrix_jacchus
ENSRNOG00000003084	Parp1	99	90.647	ENSCAFG00000016089	PARP1	100	90.956	Canis_familiaris
ENSRNOG00000003084	Parp1	100	90.542	ENSCAFG00020001660	PARP1	100	90.837	Canis_lupus_dingo
ENSRNOG00000003084	Parp1	100	87.623	ENSCHIG00000018072	PARP1	100	87.819	Capra_hircus
ENSRNOG00000003084	Parp1	99	90.761	ENSTSYG00000003699	PARP1	99	91.218	Carlito_syrichta
ENSRNOG00000003084	Parp1	99	76.176	ENSCAPG00000011113	-	99	74.725	Cavia_aperea
ENSRNOG00000003084	Parp1	100	90.640	ENSCPOG00000015643	-	100	90.640	Cavia_porcellus
ENSRNOG00000003084	Parp1	100	91.429	ENSCCAG00000033484	PARP1	100	91.626	Cebus_capucinus
ENSRNOG00000003084	Parp1	100	91.823	ENSCATG00000038981	PARP1	100	92.020	Cercocebus_atys
ENSRNOG00000003084	Parp1	100	90.345	ENSCLAG00000006637	PARP1	100	90.542	Chinchilla_lanigera
ENSRNOG00000003084	Parp1	66	96.875	ENSCHOG00000003539	PARP1	66	96.875	Choloepus_hoffmanni
ENSRNOG00000003084	Parp1	100	78.859	ENSCPBG00000011958	PARP1	100	77.974	Chrysemys_picta_bellii
ENSRNOG00000003084	Parp1	99	91.385	ENSCANG00000041340	PARP1	100	91.590	Colobus_angolensis_palliatus
ENSRNOG00000003084	Parp1	100	95.464	ENSCGRG00001020559	Parp1	100	95.759	Cricetulus_griseus_chok1gshd
ENSRNOG00000003084	Parp1	99	95.380	ENSCGRG00000004864	Parp1	100	95.688	Cricetulus_griseus_crigri
ENSRNOG00000003084	Parp1	99	69.155	ENSCSEG00000020665	parp1	99	76.923	Cynoglossus_semilaevis
ENSRNOG00000003084	Parp1	99	69.402	ENSCVAG00000021372	parp1	99	69.137	Cyprinodon_variegatus
ENSRNOG00000003084	Parp1	99	69.155	ENSDARG00000019529	parp1	99	69.587	Danio_rerio
ENSRNOG00000003084	Parp1	96	88.889	ENSDNOG00000012059	PARP1	100	89.403	Dasypus_novemcinctus
ENSRNOG00000003084	Parp1	99	88.718	ENSDORG00000005234	Parp1	100	88.923	Dipodomys_ordii
ENSRNOG00000003084	Parp1	99	41.119	FBgn0010247	Parp	99	40.824	Drosophila_melanogaster
ENSRNOG00000003084	Parp1	87	97.656	ENSETEG00000013254	PARP1	88	97.656	Echinops_telfairi
ENSRNOG00000003084	Parp1	98	57.438	ENSEBUG00000005820	parp1	100	57.214	Eptatretus_burgeri
ENSRNOG00000003084	Parp1	98	91.174	ENSEASG00005013275	PARP1	99	91.283	Equus_asinus_asinus
ENSRNOG00000003084	Parp1	100	91.429	ENSECAG00000019207	PARP1	100	91.626	Equus_caballus
ENSRNOG00000003084	Parp1	100	86.542	ENSEEUG00000012253	PARP1	100	86.739	Erinaceus_europaeus
ENSRNOG00000003084	Parp1	99	70.378	ENSELUG00000017336	parp1	98	70.273	Esox_lucius
ENSRNOG00000003084	Parp1	99	90.010	ENSFCAG00000005777	PARP1	100	90.520	Felis_catus
ENSRNOG00000003084	Parp1	99	76.254	ENSFALG00000011578	PARP1	100	76.561	Ficedula_albicollis
ENSRNOG00000003084	Parp1	99	89.026	ENSFDAG00000017662	PARP1	100	89.231	Fukomys_damarensis
ENSRNOG00000003084	Parp1	99	70.177	ENSFHEG00000001117	parp1	99	69.980	Fundulus_heteroclitus
ENSRNOG00000003084	Parp1	99	68.768	ENSGMOG00000014929	parp1	99	69.132	Gadus_morhua
ENSRNOG00000003084	Parp1	100	76.916	ENSGALG00000009228	PARP1	100	77.112	Gallus_gallus
ENSRNOG00000003084	Parp1	100	69.667	ENSGAFG00000010450	parp1	100	69.374	Gambusia_affinis
ENSRNOG00000003084	Parp1	100	68.848	ENSGACG00000011280	parp1	100	68.750	Gasterosteus_aculeatus
ENSRNOG00000003084	Parp1	100	77.953	ENSGAGG00000010066	PARP1	100	77.165	Gopherus_agassizii
ENSRNOG00000003084	Parp1	100	91.232	ENSGGOG00000006308	PARP1	100	91.429	Gorilla_gorilla
ENSRNOG00000003084	Parp1	100	71.163	ENSHBUG00000010490	parp1	100	70.813	Haplochromis_burtoni
ENSRNOG00000003084	Parp1	99	88.525	ENSHGLG00000003992	PARP1	93	88.730	Heterocephalus_glaber_female
ENSRNOG00000003084	Parp1	99	88.525	ENSHGLG00100016965	PARP1	93	88.730	Heterocephalus_glaber_male
ENSRNOG00000003084	Parp1	100	67.641	ENSHCOG00000011619	parp1	100	67.892	Hippocampus_comes
ENSRNOG00000003084	Parp1	100	68.155	ENSIPUG00000020250	parp1	100	68.252	Ictalurus_punctatus
ENSRNOG00000003084	Parp1	100	91.527	ENSSTOG00000016000	PARP1	100	91.724	Ictidomys_tridecemlineatus
ENSRNOG00000003084	Parp1	100	92.217	ENSJJAG00000023497	Parp1	100	92.414	Jaculus_jaculus
ENSRNOG00000003084	Parp1	99	70.276	ENSKMAG00000011627	parp1	99	70.276	Kryptolebias_marmoratus
ENSRNOG00000003084	Parp1	100	69.706	ENSLBEG00000013376	parp1	100	70.000	Labrus_bergylta
ENSRNOG00000003084	Parp1	99	58.391	ENSLACG00000002735	PARP1	100	58.587	Latimeria_chalumnae
ENSRNOG00000003084	Parp1	99	71.795	ENSLOCG00000015798	parp1	99	71.303	Lepisosteus_oculatus
ENSRNOG00000003084	Parp1	99	88.410	ENSLAFG00000007830	PARP1	100	88.615	Loxodonta_africana
ENSRNOG00000003084	Parp1	100	91.823	ENSMFAG00000002526	PARP1	100	92.020	Macaca_fascicularis
ENSRNOG00000003084	Parp1	100	91.921	ENSMMUG00000021820	PARP1	100	92.118	Macaca_mulatta
ENSRNOG00000003084	Parp1	100	91.921	ENSMNEG00000034074	PARP1	100	92.118	Macaca_nemestrina
ENSRNOG00000003084	Parp1	100	89.784	ENSMLEG00000012344	PARP1	100	89.980	Mandrillus_leucophaeus
ENSRNOG00000003084	Parp1	100	70.206	ENSMAMG00000020652	parp1	100	70.108	Mastacembelus_armatus
ENSRNOG00000003084	Parp1	100	71.359	ENSMZEG00005016907	parp1	100	71.009	Maylandia_zebra
ENSRNOG00000003084	Parp1	99	77.789	ENSMGAG00000007760	PARP1	100	77.380	Meleagris_gallopavo
ENSRNOG00000003084	Parp1	100	95.661	ENSMAUG00000008306	Parp1	100	95.957	Mesocricetus_auratus
ENSRNOG00000003084	Parp1	100	87.685	ENSMICG00000017076	PARP1	100	87.882	Microcebus_murinus
ENSRNOG00000003084	Parp1	100	94.773	ENSMOCG00000014315	Parp1	100	95.069	Microtus_ochrogaster
ENSRNOG00000003084	Parp1	100	69.314	ENSMMOG00000015966	parp1	100	69.216	Mola_mola
ENSRNOG00000003084	Parp1	100	81.201	ENSMODG00000006076	PARP1	100	82.399	Monodelphis_domestica
ENSRNOG00000003084	Parp1	100	67.546	ENSMALG00000004057	parp1	100	67.777	Monopterus_albus
ENSRNOG00000003084	Parp1	100	96.943	MGP_CAROLIEiJ_G0014978	Parp1	100	97.959	Mus_caroli
ENSRNOG00000003084	Parp1	100	97.041	ENSMUSG00000026496	Parp1	100	97.041	Mus_musculus
ENSRNOG00000003084	Parp1	100	97.041	MGP_SPRETEiJ_G0015777	Parp1	100	97.959	Mus_spretus
ENSRNOG00000003084	Parp1	100	89.754	ENSMPUG00000004585	PARP1	100	89.655	Mustela_putorius_furo
ENSRNOG00000003084	Parp1	90	74.482	ENSMLUG00000012285	PARP1	100	74.726	Myotis_lucifugus
ENSRNOG00000003084	Parp1	100	93.195	ENSNGAG00000003885	Parp1	100	93.393	Nannospalax_galili
ENSRNOG00000003084	Parp1	100	71.232	ENSNBRG00000017434	parp1	100	70.936	Neolamprologus_brichardi
ENSRNOG00000003084	Parp1	95	93.915	ENSNLEG00000013905	PARP1	100	93.915	Nomascus_leucogenys
ENSRNOG00000003084	Parp1	67	92.239	ENSMEUG00000007720	PARP1	87	92.239	Notamacropus_eugenii
ENSRNOG00000003084	Parp1	100	91.133	ENSOPRG00000011722	PARP1	100	91.330	Ochotona_princeps
ENSRNOG00000003084	Parp1	100	87.094	ENSODEG00000007424	PARP1	100	87.291	Octodon_degus
ENSRNOG00000003084	Parp1	100	71.205	ENSONIG00000013486	parp1	100	70.715	Oreochromis_niloticus
ENSRNOG00000003084	Parp1	99	81.186	ENSOANG00000001488	PARP1	100	81.493	Ornithorhynchus_anatinus
ENSRNOG00000003084	Parp1	100	91.634	ENSOCUG00000017820	PARP1	100	91.929	Oryctolagus_cuniculus
ENSRNOG00000003084	Parp1	100	69.193	ENSORLG00000013691	parp1	100	69.080	Oryzias_latipes
ENSRNOG00000003084	Parp1	99	68.976	ENSORLG00020001074	parp1	99	68.857	Oryzias_latipes_hni
ENSRNOG00000003084	Parp1	100	69.388	ENSORLG00015007090	parp1	100	69.276	Oryzias_latipes_hsok
ENSRNOG00000003084	Parp1	100	90.443	ENSOGAG00000016206	PARP1	100	90.640	Otolemur_garnettii
ENSRNOG00000003084	Parp1	100	87.721	ENSOARG00000000811	PARP1	100	88.016	Ovis_aries
ENSRNOG00000003084	Parp1	100	91.133	ENSPPAG00000040862	PARP1	100	91.330	Pan_paniscus
ENSRNOG00000003084	Parp1	99	89.744	ENSPPRG00000003528	PARP1	100	90.256	Panthera_pardus
ENSRNOG00000003084	Parp1	97	76.842	ENSPTIG00000009102	PARP1	98	77.053	Panthera_tigris_altaica
ENSRNOG00000003084	Parp1	100	91.133	ENSPTRG00000002049	PARP1	100	91.330	Pan_troglodytes
ENSRNOG00000003084	Parp1	100	92.028	ENSPANG00000011198	PARP1	100	92.224	Papio_anubis
ENSRNOG00000003084	Parp1	99	69.793	ENSPKIG00000006039	parp1	100	69.570	Paramormyrops_kingsleyae
ENSRNOG00000003084	Parp1	99	76.453	ENSPSIG00000016374	PARP1	100	76.656	Pelodiscus_sinensis
ENSRNOG00000003084	Parp1	100	66.278	ENSPMGG00000008936	parp1	100	66.084	Periophthalmus_magnuspinnatus
ENSRNOG00000003084	Parp1	100	94.872	ENSPEMG00000020230	Parp1	100	95.168	Peromyscus_maniculatus_bairdii
ENSRNOG00000003084	Parp1	100	81.213	ENSPCIG00000006436	PARP1	100	87.021	Phascolarctos_cinereus
ENSRNOG00000003084	Parp1	99	69.587	ENSPFOG00000002342	parp1	99	69.193	Poecilia_formosa
ENSRNOG00000003084	Parp1	99	70.334	ENSPLAG00000000909	parp1	99	69.980	Poecilia_latipinna
ENSRNOG00000003084	Parp1	99	70.472	ENSPMEG00000013979	parp1	99	70.177	Poecilia_mexicana
ENSRNOG00000003084	Parp1	99	70.374	ENSPREG00000001114	parp1	99	70.079	Poecilia_reticulata
ENSRNOG00000003084	Parp1	99	91.881	ENSPPYG00000000164	PARP1	100	92.086	Pongo_abelii
ENSRNOG00000003084	Parp1	65	95.679	ENSPCAG00000005558	-	65	95.679	Procavia_capensis
ENSRNOG00000003084	Parp1	100	91.527	ENSPCOG00000016918	PARP1	100	91.724	Propithecus_coquereli
ENSRNOG00000003084	Parp1	92	95.755	ENSPVAG00000005543	PARP1	85	95.755	Pteropus_vampyrus
ENSRNOG00000003084	Parp1	100	71.330	ENSPNYG00000009702	parp1	100	71.034	Pundamilia_nyererei
ENSRNOG00000003084	Parp1	99	69.185	ENSPNAG00000002787	parp1	99	69.276	Pygocentrus_nattereri
ENSRNOG00000003084	Parp1	100	91.626	ENSRBIG00000044893	PARP1	100	91.823	Rhinopithecus_bieti
ENSRNOG00000003084	Parp1	100	91.626	ENSRROG00000029280	PARP1	100	91.823	Rhinopithecus_roxellana
ENSRNOG00000003084	Parp1	100	65.093	ENSRROG00000040615	-	100	67.640	Rhinopithecus_roxellana
ENSRNOG00000003084	Parp1	100	91.429	ENSSBOG00000010144	PARP1	100	91.626	Saimiri_boliviensis_boliviensis
ENSRNOG00000003084	Parp1	99	82.667	ENSSHAG00000001991	PARP1	100	83.504	Sarcophilus_harrisii
ENSRNOG00000003084	Parp1	100	70.674	ENSSFOG00015020017	parp1	100	70.186	Scleropages_formosus
ENSRNOG00000003084	Parp1	100	69.931	ENSSMAG00000013799	parp1	100	69.931	Scophthalmus_maximus
ENSRNOG00000003084	Parp1	100	69.246	ENSSDUG00000016626	parp1	100	69.148	Seriola_dumerili
ENSRNOG00000003084	Parp1	100	69.246	ENSSLDG00000006384	parp1	100	69.148	Seriola_lalandi_dorsalis
ENSRNOG00000003084	Parp1	54	94.213	ENSSARG00000009436	-	58	100.000	Sorex_araneus
ENSRNOG00000003084	Parp1	100	74.114	ENSSPUG00000007790	PARP1	100	74.409	Sphenodon_punctatus
ENSRNOG00000003084	Parp1	100	68.204	ENSSPAG00000019074	parp1	100	69.551	Stegastes_partitus
ENSRNOG00000003084	Parp1	100	89.951	ENSSSCG00000023660	PARP1	100	90.246	Sus_scrofa
ENSRNOG00000003084	Parp1	97	77.137	ENSTGUG00000004260	-	100	77.358	Taeniopygia_guttata
ENSRNOG00000003084	Parp1	100	68.137	ENSTRUG00000014490	parp1	100	68.333	Takifugu_rubripes
ENSRNOG00000003084	Parp1	100	68.750	ENSTNIG00000016384	parp1	100	68.555	Tetraodon_nigroviridis
ENSRNOG00000003084	Parp1	89	92.553	ENSTBEG00000002364	PARP1	92	94.521	Tupaia_belangeri
ENSRNOG00000003084	Parp1	100	85.025	ENSTTRG00000000188	PARP1	100	84.335	Tursiops_truncatus
ENSRNOG00000003084	Parp1	99	90.164	ENSUAMG00000014388	PARP1	100	90.369	Ursus_americanus
ENSRNOG00000003084	Parp1	96	80.470	ENSUMAG00000014555	PARP1	99	80.629	Ursus_maritimus
ENSRNOG00000003084	Parp1	84	96.863	ENSVPAG00000011411	PARP1	84	96.863	Vicugna_pacos
ENSRNOG00000003084	Parp1	96	90.545	ENSVVUG00000001655	PARP1	100	90.853	Vulpes_vulpes
ENSRNOG00000003084	Parp1	98	72.745	ENSXETG00000022610	parp1	99	72.846	Xenopus_tropicalis
ENSRNOG00000003084	Parp1	99	69.587	ENSXMAG00000003632	parp1	99	69.291	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000723	telomere maintenance	-	ISO	Process
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	-	IEA	Function
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	-	ISO	Function
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	-	IEA	Function
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	-	ISO	Function
GO:0003682	chromatin binding	-	ISO	Function
GO:0003950	NAD+ ADP-ribosyltransferase activity	21873635.	IBA	Function
GO:0003950	NAD+ ADP-ribosyltransferase activity	15857403.16302026.	IDA	Function
GO:0003950	NAD+ ADP-ribosyltransferase activity	22073128.	IMP	Function
GO:0003950	NAD+ ADP-ribosyltransferase activity	-	ISO	Function
GO:0005515	protein binding	25625556.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	16093393.16302026.22073128.	IDA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005635	nuclear envelope	-	IEA	Component
GO:0005635	nuclear envelope	-	ISO	Component
GO:0005654	nucleoplasm	-	ISO	Component
GO:0005667	transcription factor complex	-	IEA	Component
GO:0005667	transcription factor complex	-	ISO	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	-	ISO	Component
GO:0005737	cytoplasm	24842055.	IDA	Component
GO:0005737	cytoplasm	-	ISO	Component
GO:0005739	mitochondrion	-	IEA	Component
GO:0005739	mitochondrion	-	ISO	Component
GO:0006259	DNA metabolic process	-	ISO	Process
GO:0006284	base-excision repair	-	ISO	Process
GO:0006302	double-strand break repair	21873635.	IBA	Process
GO:0006302	double-strand break repair	-	ISO	Process
GO:0006302	double-strand break repair	-	ISS	Process
GO:0006471	protein ADP-ribosylation	15857403.16093393.	IDA	Process
GO:0006471	protein ADP-ribosylation	22073128.	IMP	Process
GO:0006471	protein ADP-ribosylation	-	ISO	Process
GO:0006915	apoptotic process	-	IEA	Process
GO:0006915	apoptotic process	-	ISO	Process
GO:0006974	cellular response to DNA damage stimulus	-	ISO	Process
GO:0006974	cellular response to DNA damage stimulus	-	ISS	Process
GO:0007005	mitochondrion organization	-	ISO	Process
GO:0007179	transforming growth factor beta receptor signaling pathway	22073128.	IMP	Process
GO:0008134	transcription factor binding	-	ISO	Function
GO:0008270	zinc ion binding	-	IEA	Function
GO:0010332	response to gamma radiation	14994994.	IEP	Process
GO:0010613	positive regulation of cardiac muscle hypertrophy	25625556.	IMP	Process
GO:0010990	regulation of SMAD protein complex assembly	22073128.	IMP	Process
GO:0016540	protein autoprocessing	16093393.	IDA	Process
GO:0016763	transferase activity, transferring pentosyl groups	9385436.	NAS	Function
GO:0018312	peptidyl-serine ADP-ribosylation	-	ISO	Process
GO:0018312	peptidyl-serine ADP-ribosylation	-	ISS	Process
GO:0018424	peptidyl-glutamic acid poly-ADP-ribosylation	-	ISO	Process
GO:0018424	peptidyl-glutamic acid poly-ADP-ribosylation	-	ISS	Process
GO:0019899	enzyme binding	19470756.	IPI	Function
GO:0019899	enzyme binding	-	ISO	Function
GO:0019901	protein kinase binding	-	IEA	Function
GO:0019901	protein kinase binding	-	ISO	Function
GO:0023019	signal transduction involved in regulation of gene expression	22073128.	IMP	Process
GO:0030331	estrogen receptor binding	23493398.	IPI	Function
GO:0030592	DNA ADP-ribosylation	-	ISO	Process
GO:0030592	DNA ADP-ribosylation	-	ISS	Process
GO:0032042	mitochondrial DNA metabolic process	-	ISO	Process
GO:0032869	cellular response to insulin stimulus	-	IEA	Process
GO:0032869	cellular response to insulin stimulus	-	ISO	Process
GO:0032991	protein-containing complex	-	ISO	Component
GO:0032993	protein-DNA complex	-	IEA	Component
GO:0032993	protein-DNA complex	-	ISO	Component
GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	23493398.	IMP	Process
GO:0034599	cellular response to oxidative stress	-	IEA	Process
GO:0034599	cellular response to oxidative stress	-	ISO	Process
GO:0034644	cellular response to UV	-	IEA	Process
GO:0034644	cellular response to UV	-	ISO	Process
GO:0035861	site of double-strand break	-	IEA	Component
GO:0035861	site of double-strand break	-	ISO	Component
GO:0036211	protein modification process	-	ISO	Process
GO:0040009	regulation of growth rate	-	ISO	Process
GO:0042769	DNA damage response, detection of DNA damage	15857403.	IDA	Process
GO:0042802	identical protein binding	-	IEA	Function
GO:0042802	identical protein binding	-	ISO	Function
GO:0042826	histone deacetylase binding	19470756.	IPI	Function
GO:0043504	mitochondrial DNA repair	-	IEA	Process
GO:0043504	mitochondrial DNA repair	-	ISO	Process
GO:0044030	regulation of DNA methylation	23260200.	IMP	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	22073128.	IMP	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	-	ISO	Process
GO:0046332	SMAD binding	22073128.	IPI	Function
GO:0047485	protein N-terminus binding	-	IEA	Function
GO:0047485	protein N-terminus binding	-	ISO	Function
GO:0048148	behavioral response to cocaine	-	ISO	Process
GO:0050790	regulation of catalytic activity	-	IEA	Process
GO:0050790	regulation of catalytic activity	-	ISO	Process
GO:0050882	voluntary musculoskeletal movement	-	ISO	Process
GO:0051287	NAD binding	15857403.16302026.	IDA	Function
GO:0051901	positive regulation of mitochondrial depolarization	21616968.	IMP	Process
GO:0060391	positive regulation of SMAD protein signal transduction	22073128.	IMP	Process
GO:0070212	protein poly-ADP-ribosylation	21873635.	IBA	Process
GO:0070212	protein poly-ADP-ribosylation	22073128.	IMP	Process
GO:0070212	protein poly-ADP-ribosylation	-	ISO	Process
GO:0070212	protein poly-ADP-ribosylation	-	ISS	Process
GO:0070213	protein auto-ADP-ribosylation	-	ISO	Process
GO:0070213	protein auto-ADP-ribosylation	-	ISS	Process
GO:0070412	R-SMAD binding	22073128.	IPI	Function
GO:0071294	cellular response to zinc ion	23582235.	IEP	Process
GO:0071451	cellular response to superoxide	-	ISO	Process
GO:0071560	cellular response to transforming growth factor beta stimulus	22073128.	IMP	Process
GO:0090734	site of DNA damage	-	ISO	Component
GO:0090734	site of DNA damage	-	ISS	Component
GO:1900182	positive regulation of protein localization to nucleus	22073128.	IMP	Process
GO:1901216	positive regulation of neuron death	21616968.	IMP	Process
GO:1903376	regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	17347665.	IMP	Process
GO:1903516	regulation of single strand break repair	-	ISO	Process
GO:1903518	positive regulation of single strand break repair	-	IEA	Process
GO:1903518	positive regulation of single strand break repair	-	ISO	Process
GO:1903827	regulation of cellular protein localization	-	ISO	Process
GO:1904044	response to aldosterone	14994994.	IEP	Process
GO:1904357	negative regulation of telomere maintenance via telomere lengthening	-	ISO	Process
GO:1904646	cellular response to amyloid-beta	21616968.	IMP	Process
GO:1904762	positive regulation of myofibroblast differentiation	23260200.	IMP	Process
GO:1905077	negative regulation of interleukin-17 secretion	-	ISO	Process
GO:1905168	positive regulation of double-strand break repair via homologous recombination	-	ISO	Process
GO:1905168	positive regulation of double-strand break repair via homologous recombination	-	ISS	Process
GO:1990404	protein ADP-ribosylase activity	21873635.	IBA	Function
GO:1990404	protein ADP-ribosylase activity	-	ISO	Function
GO:1990404	protein ADP-ribosylase activity	-	ISS	Function
GO:1990966	ATP generation from poly-ADP-D-ribose	-	ISO	Process
GO:1990966	ATP generation from poly-ADP-D-ribose	-	ISS	Process
GO:2000679	positive regulation of transcription regulatory region DNA binding	22073128.	IMP	Process
GO:2001170	negative regulation of ATP biosynthetic process	-	IEA	Process
GO:2001170	negative regulation of ATP biosynthetic process	-	ISO	Process