EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSRNOG00000009451 (Gene tree)
Gene ID: 298374
Gene Symbol: Prpf38a
Alias: LOC298374|RGD1311129
Full Name: pre-mRNA processing factor 38A
Gene Type: protein_coding
Species: Rattus_norvegicus
Status: putative
Strand: Minus strand
Length: 11698 bases
Position: chr5:128174835-128186532
Accession: 1311129
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSRNOP00000012635	PRP38	PF03371.15	7.5e-63	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSRNOT00000012635	-	1656	-	ENSRNOP00000012635	312 (aa)	-	D3ZGL5

Gene Model

Click here to download ENSRNOG00000009451's gene model file

Pathways

Pathway ID	Pathway Name	Source
rno03040	Spliceosome	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSRNOG00000009451's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSRNOG00000009451	Prpf38a	100	99.359	ENSG00000134748	PRPF38A	100	99.359	Homo_sapiens
ENSRNOG00000009451	Prpf38a	71	89.140	ENSAPOG00000011652	prpf38a	100	82.109	Acanthochromis_polyacanthus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSAMEG00000009319	PRPF38A	100	99.359	Ailuropoda_melanoleuca
ENSRNOG00000009451	Prpf38a	71	86.878	ENSACIG00000012292	prpf38a	76	86.147	Amphilophus_citrinellus
ENSRNOG00000009451	Prpf38a	71	89.140	ENSAOCG00000018004	prpf38a	100	82.109	Amphiprion_ocellaris
ENSRNOG00000009451	Prpf38a	71	89.140	ENSAPEG00000021414	prpf38a	100	82.109	Amphiprion_percula
ENSRNOG00000009451	Prpf38a	71	89.593	ENSATEG00000004608	prpf38a	100	82.109	Anabas_testudineus
ENSRNOG00000009451	Prpf38a	79	97.976	ENSAPLG00000005827	PRPF38A	99	97.976	Anas_platyrhynchos
ENSRNOG00000009451	Prpf38a	100	95.192	ENSACAG00000008249	PRPF38A	100	95.192	Anolis_carolinensis
ENSRNOG00000009451	Prpf38a	100	99.359	ENSANAG00000027839	PRPF38A	100	99.359	Aotus_nancymaae
ENSRNOG00000009451	Prpf38a	100	68.354	ENSANAG00000029204	-	100	62.975	Aotus_nancymaae
ENSRNOG00000009451	Prpf38a	71	86.878	ENSACLG00000021595	prpf38a	100	80.511	Astatotilapia_calliptera
ENSRNOG00000009451	Prpf38a	100	82.748	ENSAMXG00000029274	prpf38a	100	82.748	Astyanax_mexicanus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSBTAG00000002720	PRPF38A	100	99.359	Bos_taurus
ENSRNOG00000009451	Prpf38a	63	62.051	WBGene00008380	prp-38	67	61.111	Caenorhabditis_elegans
ENSRNOG00000009451	Prpf38a	100	99.359	ENSCJAG00000021594	PRPF38A	100	99.359	Callithrix_jacchus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSCAFG00000003740	PRPF38A	100	99.359	Canis_familiaris
ENSRNOG00000009451	Prpf38a	100	99.359	ENSCAFG00020010939	PRPF38A	100	99.359	Canis_lupus_dingo
ENSRNOG00000009451	Prpf38a	100	99.359	ENSCHIG00000024730	PRPF38A	100	99.359	Capra_hircus
ENSRNOG00000009451	Prpf38a	86	98.141	ENSTSYG00000031994	-	95	98.141	Carlito_syrichta
ENSRNOG00000009451	Prpf38a	100	99.359	ENSTSYG00000009868	-	100	99.359	Carlito_syrichta
ENSRNOG00000009451	Prpf38a	100	99.359	ENSCPOG00000005079	PRPF38A	100	99.359	Cavia_porcellus
ENSRNOG00000009451	Prpf38a	100	99.038	ENSCCAG00000026502	PRPF38A	100	99.038	Cebus_capucinus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSCATG00000032296	PRPF38A	100	99.359	Cercocebus_atys
ENSRNOG00000009451	Prpf38a	100	64.103	ENSCATG00000044190	-	100	62.821	Cercocebus_atys
ENSRNOG00000009451	Prpf38a	100	99.359	ENSCLAG00000005816	PRPF38A	100	99.359	Chinchilla_lanigera
ENSRNOG00000009451	Prpf38a	78	96.875	ENSCHOG00000008388	PRPF38A	77	96.875	Choloepus_hoffmanni
ENSRNOG00000009451	Prpf38a	100	98.077	ENSCPBG00000014791	PRPF38A	100	98.077	Chrysemys_picta_bellii
ENSRNOG00000009451	Prpf38a	67	71.905	ENSCSAVG00000009580	-	78	66.102	Ciona_savignyi
ENSRNOG00000009451	Prpf38a	96	99.331	ENSCANG00000032608	PRPF38A	100	99.331	Colobus_angolensis_palliatus
ENSRNOG00000009451	Prpf38a	74	84.848	ENSCGRG00001002557	-	78	84.848	Cricetulus_griseus_chok1gshd
ENSRNOG00000009451	Prpf38a	100	99.679	ENSCGRG00001018502	-	100	99.679	Cricetulus_griseus_chok1gshd
ENSRNOG00000009451	Prpf38a	100	99.679	ENSCGRG00000014868	Prpf38a	100	99.679	Cricetulus_griseus_crigri
ENSRNOG00000009451	Prpf38a	71	88.235	ENSCSEG00000001269	prpf38a	79	87.446	Cynoglossus_semilaevis
ENSRNOG00000009451	Prpf38a	71	90.950	ENSCVAG00000012305	prpf38a	100	82.748	Cyprinodon_variegatus
ENSRNOG00000009451	Prpf38a	100	82.109	ENSDARG00000039213	prpf38a	100	82.109	Danio_rerio
ENSRNOG00000009451	Prpf38a	100	99.359	ENSDNOG00000042326	PRPF38A	100	99.359	Dasypus_novemcinctus
ENSRNOG00000009451	Prpf38a	100	85.897	ENSDORG00000023857	-	100	85.897	Dipodomys_ordii
ENSRNOG00000009451	Prpf38a	84	83.270	ENSDORG00000025371	-	78	87.665	Dipodomys_ordii
ENSRNOG00000009451	Prpf38a	84	83.270	ENSDORG00000023691	-	78	87.665	Dipodomys_ordii
ENSRNOG00000009451	Prpf38a	63	75.127	FBgn0050342	Prp38	57	76.064	Drosophila_melanogaster
ENSRNOG00000009451	Prpf38a	76	81.513	ENSEBUG00000012588	prpf38a	75	81.545	Eptatretus_burgeri
ENSRNOG00000009451	Prpf38a	100	99.359	ENSEASG00005014427	PRPF38A	100	99.359	Equus_asinus_asinus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSECAG00000022628	PRPF38A	100	99.359	Equus_caballus
ENSRNOG00000009451	Prpf38a	71	87.330	ENSELUG00000021094	prpf38a	100	80.831	Esox_lucius
ENSRNOG00000009451	Prpf38a	100	99.359	ENSFCAG00000002518	PRPF38A	100	99.359	Felis_catus
ENSRNOG00000009451	Prpf38a	87	97.048	ENSFALG00000005598	-	100	97.048	Ficedula_albicollis
ENSRNOG00000009451	Prpf38a	99	85.209	ENSFALG00000003612	-	77	90.476	Ficedula_albicollis
ENSRNOG00000009451	Prpf38a	100	99.038	ENSFDAG00000011287	PRPF38A	100	99.038	Fukomys_damarensis
ENSRNOG00000009451	Prpf38a	84	79.167	ENSFHEG00000014317	prpf38a	78	89.177	Fundulus_heteroclitus
ENSRNOG00000009451	Prpf38a	53	95.181	ENSGMOG00000011384	prpf38a	54	95.181	Gadus_morhua
ENSRNOG00000009451	Prpf38a	100	98.397	ENSGALG00000010627	PRPF38A	100	98.397	Gallus_gallus
ENSRNOG00000009451	Prpf38a	71	90.950	ENSGAFG00000012422	prpf38a	100	82.748	Gambusia_affinis
ENSRNOG00000009451	Prpf38a	71	86.547	ENSGACG00000005423	prpf38a	100	80.000	Gasterosteus_aculeatus
ENSRNOG00000009451	Prpf38a	100	98.397	ENSGAGG00000020547	PRPF38A	100	98.397	Gopherus_agassizii
ENSRNOG00000009451	Prpf38a	100	99.359	ENSGGOG00000003940	PRPF38A	100	99.359	Gorilla_gorilla
ENSRNOG00000009451	Prpf38a	61	91.534	ENSHBUG00000020572	prpf38a	80	91.489	Haplochromis_burtoni
ENSRNOG00000009451	Prpf38a	100	99.359	ENSHGLG00000000475	PRPF38A	100	99.359	Heterocephalus_glaber_female
ENSRNOG00000009451	Prpf38a	100	83.333	ENSHGLG00000007918	-	100	83.013	Heterocephalus_glaber_female
ENSRNOG00000009451	Prpf38a	100	83.333	ENSHGLG00100003928	-	100	83.013	Heterocephalus_glaber_male
ENSRNOG00000009451	Prpf38a	100	99.359	ENSHGLG00100008935	PRPF38A	100	99.359	Heterocephalus_glaber_male
ENSRNOG00000009451	Prpf38a	87	69.742	ENSHCOG00000020781	prpf38a	59	91.489	Hippocampus_comes
ENSRNOG00000009451	Prpf38a	74	87.931	ENSIPUG00000005757	prpf38a	75	87.931	Ictalurus_punctatus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSSTOG00000015610	PRPF38A	100	99.359	Ictidomys_tridecemlineatus
ENSRNOG00000009451	Prpf38a	100	98.718	ENSJJAG00000015811	Prpf38a	100	98.718	Jaculus_jaculus
ENSRNOG00000009451	Prpf38a	71	90.498	ENSKMAG00000006588	prpf38a	100	82.428	Kryptolebias_marmoratus
ENSRNOG00000009451	Prpf38a	96	79.530	ENSLBEG00000020585	prpf38a	100	79.872	Labrus_bergylta
ENSRNOG00000009451	Prpf38a	100	92.628	ENSLACG00000011495	PRPF38A	100	92.628	Latimeria_chalumnae
ENSRNOG00000009451	Prpf38a	100	80.511	ENSLOCG00000006262	prpf38a	100	81.789	Lepisosteus_oculatus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSLAFG00000025862	PRPF38A	100	99.359	Loxodonta_africana
ENSRNOG00000009451	Prpf38a	100	99.359	ENSMFAG00000039449	PRPF38A	100	99.359	Macaca_fascicularis
ENSRNOG00000009451	Prpf38a	87	98.529	ENSMMUG00000014333	PRPF38A	98	98.529	Macaca_mulatta
ENSRNOG00000009451	Prpf38a	100	64.423	ENSMNEG00000040242	-	100	63.462	Macaca_nemestrina
ENSRNOG00000009451	Prpf38a	100	99.359	ENSMNEG00000031221	PRPF38A	100	99.359	Macaca_nemestrina
ENSRNOG00000009451	Prpf38a	100	99.359	ENSMLEG00000041105	PRPF38A	100	99.359	Mandrillus_leucophaeus
ENSRNOG00000009451	Prpf38a	71	88.688	ENSMAMG00000015431	prpf38a	100	81.789	Mastacembelus_armatus
ENSRNOG00000009451	Prpf38a	71	86.878	ENSMZEG00005017838	prpf38a	100	80.511	Maylandia_zebra
ENSRNOG00000009451	Prpf38a	96	98.328	ENSMGAG00000011176	PRPF38A	100	98.328	Meleagris_gallopavo
ENSRNOG00000009451	Prpf38a	85	94.697	ENSMAUG00000018029	-	87	94.805	Mesocricetus_auratus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSMICG00000014193	PRPF38A	100	99.359	Microcebus_murinus
ENSRNOG00000009451	Prpf38a	100	99.679	ENSMOCG00000013080	Prpf38a	100	99.679	Microtus_ochrogaster
ENSRNOG00000009451	Prpf38a	83	82.171	ENSMMOG00000016972	prpf38a	81	87.879	Mola_mola
ENSRNOG00000009451	Prpf38a	100	97.764	ENSMODG00000000644	PRPF38A	100	97.764	Monodelphis_domestica
ENSRNOG00000009451	Prpf38a	71	88.688	ENSMALG00000019363	prpf38a	97	81.789	Monopterus_albus
ENSRNOG00000009451	Prpf38a	100	99.359	MGP_CAROLIEiJ_G0026269	Prpf38a	100	99.359	Mus_caroli
ENSRNOG00000009451	Prpf38a	100	99.359	ENSMUSG00000063800	Prpf38a	100	99.359	Mus_musculus
ENSRNOG00000009451	Prpf38a	100	99.359	MGP_PahariEiJ_G0028602	Prpf38a	100	99.359	Mus_pahari
ENSRNOG00000009451	Prpf38a	100	99.038	MGP_SPRETEiJ_G0027238	Prpf38a	100	99.038	Mus_spretus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSMPUG00000006896	PRPF38A	100	99.359	Mustela_putorius_furo
ENSRNOG00000009451	Prpf38a	100	99.679	ENSNGAG00000011884	Prpf38a	100	99.679	Nannospalax_galili
ENSRNOG00000009451	Prpf38a	71	85.520	ENSNBRG00000004013	prpf38a	74	84.848	Neolamprologus_brichardi
ENSRNOG00000009451	Prpf38a	97	73.179	ENSNLEG00000012592	-	99	73.179	Nomascus_leucogenys
ENSRNOG00000009451	Prpf38a	100	66.987	ENSNLEG00000033398	-	94	66.987	Nomascus_leucogenys
ENSRNOG00000009451	Prpf38a	93	99.308	ENSNLEG00000017999	PRPF38A	93	99.308	Nomascus_leucogenys
ENSRNOG00000009451	Prpf38a	100	94.872	ENSMEUG00000003860	PRPF38A	100	94.872	Notamacropus_eugenii
ENSRNOG00000009451	Prpf38a	77	99.583	ENSOPRG00000008985	PRPF38A	100	99.583	Ochotona_princeps
ENSRNOG00000009451	Prpf38a	100	99.359	ENSODEG00000005869	PRPF38A	100	99.359	Octodon_degus
ENSRNOG00000009451	Prpf38a	71	87.330	ENSONIG00000007816	prpf38a	100	80.831	Oreochromis_niloticus
ENSRNOG00000009451	Prpf38a	100	64.968	ENSOANG00000009541	-	100	64.968	Ornithorhynchus_anatinus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSOCUG00000000963	PRPF38A	100	99.359	Oryctolagus_cuniculus
ENSRNOG00000009451	Prpf38a	96	82.667	ENSORLG00000013485	prpf38a	99	82.692	Oryzias_latipes
ENSRNOG00000009451	Prpf38a	96	82.667	ENSORLG00020002130	prpf38a	99	82.692	Oryzias_latipes_hni
ENSRNOG00000009451	Prpf38a	96	82.333	ENSORLG00015021393	prpf38a	99	82.372	Oryzias_latipes_hsok
ENSRNOG00000009451	Prpf38a	96	82.215	ENSOMEG00000016333	prpf38a	100	82.109	Oryzias_melastigma
ENSRNOG00000009451	Prpf38a	100	99.359	ENSOGAG00000005423	PRPF38A	100	99.359	Otolemur_garnettii
ENSRNOG00000009451	Prpf38a	100	99.359	ENSOARG00000005373	PRPF38A	100	99.359	Ovis_aries
ENSRNOG00000009451	Prpf38a	100	77.244	ENSPPAG00000033867	-	100	77.244	Pan_paniscus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSPPAG00000030905	PRPF38A	100	99.359	Pan_paniscus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSPPRG00000013268	PRPF38A	100	99.359	Panthera_pardus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSPTIG00000015419	PRPF38A	100	99.359	Panthera_tigris_altaica
ENSRNOG00000009451	Prpf38a	100	99.359	ENSPTRG00000000739	PRPF38A	100	99.359	Pan_troglodytes
ENSRNOG00000009451	Prpf38a	100	99.359	ENSPANG00000015483	PRPF38A	100	99.359	Papio_anubis
ENSRNOG00000009451	Prpf38a	100	79.167	ENSPKIG00000011439	prpf38a	100	80.449	Paramormyrops_kingsleyae
ENSRNOG00000009451	Prpf38a	100	97.756	ENSPSIG00000017487	PRPF38A	100	97.756	Pelodiscus_sinensis
ENSRNOG00000009451	Prpf38a	70	89.862	ENSPMGG00000021352	prpf38a	99	78.964	Periophthalmus_magnuspinnatus
ENSRNOG00000009451	Prpf38a	100	99.679	ENSPEMG00000023277	-	100	99.679	Peromyscus_maniculatus_bairdii
ENSRNOG00000009451	Prpf38a	100	93.651	ENSPEMG00000011212	-	100	93.651	Peromyscus_maniculatus_bairdii
ENSRNOG00000009451	Prpf38a	100	97.444	ENSPCIG00000022369	-	100	97.444	Phascolarctos_cinereus
ENSRNOG00000009451	Prpf38a	83	81.853	ENSPFOG00000004248	prpf38a	100	82.748	Poecilia_formosa
ENSRNOG00000009451	Prpf38a	92	77.397	ENSPLAG00000010328	prpf38a	100	82.748	Poecilia_latipinna
ENSRNOG00000009451	Prpf38a	84	79.699	ENSPMEG00000011804	prpf38a	100	82.748	Poecilia_mexicana
ENSRNOG00000009451	Prpf38a	95	74.000	ENSPREG00000002835	prpf38a	58	94.681	Poecilia_reticulata
ENSRNOG00000009451	Prpf38a	100	90.852	ENSPPYG00000001348	PRPF38A	100	90.852	Pongo_abelii
ENSRNOG00000009451	Prpf38a	100	98.718	ENSPCAG00000013328	PRPF38A	100	98.718	Procavia_capensis
ENSRNOG00000009451	Prpf38a	100	76.282	ENSPCOG00000020709	-	76	80.519	Propithecus_coquereli
ENSRNOG00000009451	Prpf38a	100	99.359	ENSPCOG00000016387	-	100	99.359	Propithecus_coquereli
ENSRNOG00000009451	Prpf38a	100	99.359	ENSPVAG00000009803	PRPF38A	100	99.359	Pteropus_vampyrus
ENSRNOG00000009451	Prpf38a	71	86.878	ENSPNYG00000005571	prpf38a	100	80.511	Pundamilia_nyererei
ENSRNOG00000009451	Prpf38a	100	82.748	ENSPNAG00000010399	prpf38a	100	82.748	Pygocentrus_nattereri
ENSRNOG00000009451	Prpf38a	100	99.359	ENSRBIG00000036442	PRPF38A	100	99.359	Rhinopithecus_bieti
ENSRNOG00000009451	Prpf38a	100	62.179	ENSRBIG00000034053	-	100	58.974	Rhinopithecus_bieti
ENSRNOG00000009451	Prpf38a	100	99.359	ENSRROG00000032788	PRPF38A	100	99.359	Rhinopithecus_roxellana
ENSRNOG00000009451	Prpf38a	98	78.431	ENSRROG00000040003	-	99	78.431	Rhinopithecus_roxellana
ENSRNOG00000009451	Prpf38a	100	99.359	ENSSBOG00000019515	PRPF38A	100	99.359	Saimiri_boliviensis_boliviensis
ENSRNOG00000009451	Prpf38a	96	70.724	ENSSHAG00000006029	-	74	81.448	Sarcophilus_harrisii
ENSRNOG00000009451	Prpf38a	87	97.048	ENSSHAG00000006906	-	100	97.048	Sarcophilus_harrisii
ENSRNOG00000009451	Prpf38a	100	79.233	ENSSFOG00015013572	prpf38a	100	79.872	Scleropages_formosus
ENSRNOG00000009451	Prpf38a	71	88.235	ENSSMAG00000015379	prpf38a	75	87.446	Scophthalmus_maximus
ENSRNOG00000009451	Prpf38a	71	89.593	ENSSDUG00000001324	prpf38a	100	82.428	Seriola_dumerili
ENSRNOG00000009451	Prpf38a	71	89.593	ENSSLDG00000014803	prpf38a	100	82.428	Seriola_lalandi_dorsalis
ENSRNOG00000009451	Prpf38a	100	82.372	ENSSARG00000014458	PRPF38A	100	82.372	Sorex_araneus
ENSRNOG00000009451	Prpf38a	100	95.513	ENSSPUG00000013259	PRPF38A	100	95.513	Sphenodon_punctatus
ENSRNOG00000009451	Prpf38a	71	71.041	ENSSPAG00000010449	prpf38a	100	64.423	Stegastes_partitus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSSSCG00000028288	PRPF38A	100	99.359	Sus_scrofa
ENSRNOG00000009451	Prpf38a	100	93.910	ENSTGUG00000008995	PRPF38A	100	93.910	Taeniopygia_guttata
ENSRNOG00000009451	Prpf38a	71	88.688	ENSTRUG00000003374	prpf38a	71	87.879	Takifugu_rubripes
ENSRNOG00000009451	Prpf38a	71	86.996	ENSTNIG00000005533	prpf38a	100	80.317	Tetraodon_nigroviridis
ENSRNOG00000009451	Prpf38a	100	98.718	ENSTBEG00000000725	PRPF38A	100	98.718	Tupaia_belangeri
ENSRNOG00000009451	Prpf38a	100	99.359	ENSTTRG00000016139	PRPF38A	100	99.359	Tursiops_truncatus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSUAMG00000000625	PRPF38A	100	99.359	Ursus_americanus
ENSRNOG00000009451	Prpf38a	100	99.359	ENSUMAG00000022674	PRPF38A	100	99.359	Ursus_maritimus
ENSRNOG00000009451	Prpf38a	74	98.701	ENSVPAG00000000907	PRPF38A	100	93.590	Vicugna_pacos
ENSRNOG00000009451	Prpf38a	100	99.359	ENSVVUG00000004475	PRPF38A	100	99.359	Vulpes_vulpes
ENSRNOG00000009451	Prpf38a	100	84.665	ENSXETG00000008060	prpf38a	100	88.498	Xenopus_tropicalis
ENSRNOG00000009451	Prpf38a	71	88.789	ENSXCOG00000007393	prpf38a	77	87.983	Xiphophorus_couchianus
ENSRNOG00000009451	Prpf38a	71	90.950	ENSXMAG00000026143	prpf38a	100	82.748	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000398	mRNA splicing, via spliceosome	-	IEA	Process
GO:0000398	mRNA splicing, via spliceosome	-	ISO	Process
GO:0005634	nucleus	-	ISO	Component
GO:0031965	nuclear membrane	-	IEA	Component
GO:0031965	nuclear membrane	-	ISO	Component
GO:0071005	U2-type precatalytic spliceosome	-	IEA	Component
GO:0071005	U2-type precatalytic spliceosome	-	ISO	Component
GO:0071011	precatalytic spliceosome	21873635.	IBA	Component
GO:0071011	precatalytic spliceosome	-	ISO	Component