EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSRNOG00000013451 (Gene tree)
Gene ID: 310159
Gene Symbol: Drosha
Alias: Etohi2|LOC310159|RGD1307626|Rn3
Full Name: drosha ribonuclease III
Gene Type: protein_coding
Species: Rattus_norvegicus
Status: putative
Strand: Plus strand
Length: 112306 bases
Position: chr2:62887267-62999572
Accession: 1307626
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSRNOP00000050633	Ribonuclease_3	PF00636.26	1.2e-42	1	2
ENSRNOP00000050633	Ribonuclease_3	PF00636.26	1.2e-42	2	2
ENSRNOP00000050633	dsrm	PF00035.26	1.2e-14	1	1
ENSRNOP00000050633	Ribonucleas_3_3	PF14622.6	3.9e-44	1	2
ENSRNOP00000050633	Ribonucleas_3_3	PF14622.6	3.9e-44	2	2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSRNOT00000048026	-	4479	XM_006232049	ENSRNOP00000050633	1373 (aa)	XP_006232111	E9PTR3

Gene Model

Click here to download ENSRNOG00000013451's gene model file

Pathways

Pathway ID	Pathway Name	Source
rno03008	Ribosome biogenesis in eukaryotes	KEGG
rno05205	Proteoglycans in cancer	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSRNOG00000013451's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSRNOG00000013451	Drosha	100	96.288	ENSG00000113360	DROSHA	99	96.288	Homo_sapiens
ENSRNOG00000013451	Drosha	100	93.823	ENSAMEG00000006000	DROSHA	100	93.750	Ailuropoda_melanoleuca
ENSRNOG00000013451	Drosha	69	91.062	ENSACIG00000019308	drosha	95	90.683	Amphilophus_citrinellus
ENSRNOG00000013451	Drosha	99	78.465	ENSATEG00000021939	drosha	87	78.094	Anabas_testudineus
ENSRNOG00000013451	Drosha	99	85.236	ENSAPLG00000004372	DROSHA	100	85.527	Anas_platyrhynchos
ENSRNOG00000013451	Drosha	100	81.955	ENSACAG00000007970	DROSHA	100	82.027	Anolis_carolinensis
ENSRNOG00000013451	Drosha	100	93.523	ENSANAG00000020506	DROSHA	99	95.851	Aotus_nancymaae
ENSRNOG00000013451	Drosha	97	73.955	ENSACLG00000012227	drosha	88	77.474	Astatotilapia_calliptera
ENSRNOG00000013451	Drosha	99	73.926	ENSAMXG00000005582	drosha	98	73.626	Astyanax_mexicanus
ENSRNOG00000013451	Drosha	100	92.660	ENSBTAG00000017551	DROSHA	100	92.587	Bos_taurus
ENSRNOG00000013451	Drosha	60	36.611	WBGene00009163	drsh-1	76	36.742	Caenorhabditis_elegans
ENSRNOG00000013451	Drosha	100	95.852	ENSCJAG00000018881	DROSHA	98	95.852	Callithrix_jacchus
ENSRNOG00000013451	Drosha	100	94.323	ENSCAFG00020017559	DROSHA	98	98.338	Canis_lupus_dingo
ENSRNOG00000013451	Drosha	99	95.106	ENSCHIG00000022226	DROSHA	99	95.033	Capra_hircus
ENSRNOG00000013451	Drosha	100	88.445	ENSCPOG00000015051	DROSHA	94	94.248	Cavia_porcellus
ENSRNOG00000013451	Drosha	100	95.852	ENSCCAG00000027283	DROSHA	100	98.165	Cebus_capucinus
ENSRNOG00000013451	Drosha	100	96.070	ENSCATG00000016833	DROSHA	100	96.942	Cercocebus_atys
ENSRNOG00000013451	Drosha	100	96.296	ENSCLAG00000013048	DROSHA	100	96.429	Chinchilla_lanigera
ENSRNOG00000013451	Drosha	100	93.741	ENSCSAG00000017202	DROSHA	97	93.741	Chlorocebus_sabaeus
ENSRNOG00000013451	Drosha	73	89.905	ENSCHOG00000011786	DROSHA	78	89.905	Choloepus_hoffmanni
ENSRNOG00000013451	Drosha	99	86.109	ENSCPBG00000000467	DROSHA	100	86.182	Chrysemys_picta_bellii
ENSRNOG00000013451	Drosha	61	58.014	ENSCSAVG00000010638	-	99	58.852	Ciona_savignyi
ENSRNOG00000013451	Drosha	99	96.053	ENSCANG00000035071	DROSHA	100	96.942	Colobus_angolensis_palliatus
ENSRNOG00000013451	Drosha	100	97.160	ENSCGRG00001008885	Drosha	100	97.160	Cricetulus_griseus_chok1gshd
ENSRNOG00000013451	Drosha	100	97.160	ENSCGRG00000006944	Drosha	100	97.160	Cricetulus_griseus_crigri
ENSRNOG00000013451	Drosha	77	87.320	ENSCSEG00000001452	drosha	87	77.904	Cynoglossus_semilaevis
ENSRNOG00000013451	Drosha	85	79.275	ENSCVAG00000004619	drosha	88	78.630	Cyprinodon_variegatus
ENSRNOG00000013451	Drosha	89	81.446	ENSDARG00000055563	drosha	90	77.533	Danio_rerio
ENSRNOG00000013451	Drosha	99	90.424	ENSDNOG00000001537	DROSHA	99	90.424	Dasypus_novemcinctus
ENSRNOG00000013451	Drosha	99	91.654	ENSDORG00000005624	Drosha	99	91.549	Dipodomys_ordii
ENSRNOG00000013451	Drosha	92	45.881	FBgn0026722	drosha	73	54.918	Drosophila_melanogaster
ENSRNOG00000013451	Drosha	89	98.876	ENSETEG00000007814	DROSHA	89	98.876	Echinops_telfairi
ENSRNOG00000013451	Drosha	100	93.814	ENSEASG00005007149	DROSHA	99	93.814	Equus_asinus_asinus
ENSRNOG00000013451	Drosha	100	96.215	ENSECAG00000013578	DROSHA	97	96.215	Equus_caballus
ENSRNOG00000013451	Drosha	79	89.815	ENSEEUG00000006351	DROSHA	78	89.944	Erinaceus_europaeus
ENSRNOG00000013451	Drosha	67	89.066	ENSELUG00000015039	drosha	83	74.295	Esox_lucius
ENSRNOG00000013451	Drosha	100	96.143	ENSFCAG00000000360	DROSHA	99	96.143	Felis_catus
ENSRNOG00000013451	Drosha	99	85.158	ENSFALG00000012843	DROSHA	100	84.851	Ficedula_albicollis
ENSRNOG00000013451	Drosha	100	96.006	ENSFDAG00000018414	DROSHA	100	96.006	Fukomys_damarensis
ENSRNOG00000013451	Drosha	88	61.886	ENSFHEG00000003840	drosha	82	65.872	Fundulus_heteroclitus
ENSRNOG00000013451	Drosha	99	85.371	ENSGALG00000012916	DROSHA	100	85.371	Gallus_gallus
ENSRNOG00000013451	Drosha	84	80.498	ENSGAFG00000016853	drosha	88	79.508	Gambusia_affinis
ENSRNOG00000013451	Drosha	99	85.818	ENSGAGG00000005621	DROSHA	100	85.818	Gopherus_agassizii
ENSRNOG00000013451	Drosha	100	96.288	ENSGGOG00000011006	DROSHA	100	97.044	Gorilla_gorilla
ENSRNOG00000013451	Drosha	94	70.291	ENSHBUG00000015907	drosha	87	76.190	Haplochromis_burtoni
ENSRNOG00000013451	Drosha	100	95.643	ENSHGLG00000018873	DROSHA	99	95.643	Heterocephalus_glaber_female
ENSRNOG00000013451	Drosha	100	95.643	ENSHGLG00100015793	DROSHA	98	95.643	Heterocephalus_glaber_male
ENSRNOG00000013451	Drosha	85	79.431	ENSHCOG00000008454	drosha	95	78.638	Hippocampus_comes
ENSRNOG00000013451	Drosha	71	89.164	ENSIPUG00000021202	drosha	89	75.915	Ictalurus_punctatus
ENSRNOG00000013451	Drosha	75	95.745	ENSSTOG00000016323	DROSHA	100	99.630	Ictidomys_tridecemlineatus
ENSRNOG00000013451	Drosha	100	95.630	ENSJJAG00000019758	Drosha	100	95.630	Jaculus_jaculus
ENSRNOG00000013451	Drosha	90	89.588	ENSLBEG00000006606	drosha	98	75.862	Labrus_bergylta
ENSRNOG00000013451	Drosha	99	79.652	ENSLACG00000005937	DROSHA	99	79.363	Latimeria_chalumnae
ENSRNOG00000013451	Drosha	99	77.722	ENSLOCG00000012852	drosha	87	81.899	Lepisosteus_oculatus
ENSRNOG00000013451	Drosha	99	94.453	ENSLAFG00000013831	DROSHA	100	94.453	Loxodonta_africana
ENSRNOG00000013451	Drosha	100	96.070	ENSMFAG00000003055	DROSHA	99	96.070	Macaca_fascicularis
ENSRNOG00000013451	Drosha	99	94.825	ENSMMUG00000012193	DROSHA	99	98.267	Macaca_mulatta
ENSRNOG00000013451	Drosha	100	95.852	ENSMNEG00000037529	DROSHA	99	95.852	Macaca_nemestrina
ENSRNOG00000013451	Drosha	100	91.127	ENSMLEG00000024167	DROSHA	99	91.127	Mandrillus_leucophaeus
ENSRNOG00000013451	Drosha	98	74.177	ENSMAMG00000012613	drosha	95	89.752	Mastacembelus_armatus
ENSRNOG00000013451	Drosha	97	73.955	ENSMZEG00005019487	drosha	88	77.474	Maylandia_zebra
ENSRNOG00000013451	Drosha	99	85.527	ENSMGAG00000005087	DROSHA	100	85.455	Meleagris_gallopavo
ENSRNOG00000013451	Drosha	100	97.087	ENSMAUG00000002863	Drosha	100	97.087	Mesocricetus_auratus
ENSRNOG00000013451	Drosha	100	93.986	ENSMICG00000002241	DROSHA	100	93.246	Microcebus_murinus
ENSRNOG00000013451	Drosha	99	96.852	ENSMOCG00000015044	Drosha	100	96.852	Microtus_ochrogaster
ENSRNOG00000013451	Drosha	71	86.804	ENSMMOG00000004016	drosha	94	86.749	Mola_mola
ENSRNOG00000013451	Drosha	98	84.134	ENSMODG00000004807	DROSHA	99	84.109	Monodelphis_domestica
ENSRNOG00000013451	Drosha	99	73.963	ENSMALG00000010542	drosha	88	79.058	Monopterus_albus
ENSRNOG00000013451	Drosha	100	98.034	MGP_CAROLIEiJ_G0019687	Drosha	100	98.034	Mus_caroli
ENSRNOG00000013451	Drosha	100	97.888	ENSMUSG00000022191	Drosha	100	97.888	Mus_musculus
ENSRNOG00000013451	Drosha	100	98.034	MGP_PahariEiJ_G0016063	Drosha	100	98.034	Mus_pahari
ENSRNOG00000013451	Drosha	100	97.961	MGP_SPRETEiJ_G0020580	Drosha	100	97.961	Mus_spretus
ENSRNOG00000013451	Drosha	100	95.924	ENSMPUG00000015237	DROSHA	99	95.924	Mustela_putorius_furo
ENSRNOG00000013451	Drosha	100	93.033	ENSMLUG00000002581	DROSHA	99	93.033	Myotis_lucifugus
ENSRNOG00000013451	Drosha	100	83.430	ENSNGAG00000017329	Drosha	100	90.605	Nannospalax_galili
ENSRNOG00000013451	Drosha	71	72.718	ENSNBRG00000001870	drosha	95	73.608	Neolamprologus_brichardi
ENSRNOG00000013451	Drosha	100	88.274	ENSNLEG00000013963	DROSHA	100	96.840	Nomascus_leucogenys
ENSRNOG00000013451	Drosha	78	78.801	ENSMEUG00000002029	DROSHA	82	78.801	Notamacropus_eugenii
ENSRNOG00000013451	Drosha	91	96.552	ENSOPRG00000010845	DROSHA	85	96.552	Ochotona_princeps
ENSRNOG00000013451	Drosha	100	96.078	ENSODEG00000001911	DROSHA	100	96.078	Octodon_degus
ENSRNOG00000013451	Drosha	98	75.238	ENSONIG00000006578	drosha	88	80.213	Oreochromis_niloticus
ENSRNOG00000013451	Drosha	56	80.359	ENSOANG00000015744	-	100	80.359	Ornithorhynchus_anatinus
ENSRNOG00000013451	Drosha	100	92.073	ENSOCUG00000000367	DROSHA	98	92.073	Oryctolagus_cuniculus
ENSRNOG00000013451	Drosha	74	86.439	ENSORLG00000013592	drosha	79	86.486	Oryzias_latipes
ENSRNOG00000013451	Drosha	71	87.907	ENSORLG00020002854	drosha	94	88.923	Oryzias_latipes_hni
ENSRNOG00000013451	Drosha	71	89.093	ENSORLG00015003156	drosha	94	89.959	Oryzias_latipes_hsok
ENSRNOG00000013451	Drosha	74	86.537	ENSOMEG00000001062	drosha	98	72.681	Oryzias_melastigma
ENSRNOG00000013451	Drosha	88	92.922	ENSOGAG00000005424	DROSHA	99	92.922	Otolemur_garnettii
ENSRNOG00000013451	Drosha	100	93.478	ENSPPAG00000037526	DROSHA	100	95.617	Pan_paniscus
ENSRNOG00000013451	Drosha	100	96.143	ENSPPRG00000002687	DROSHA	99	96.143	Panthera_pardus
ENSRNOG00000013451	Drosha	100	96.143	ENSPTIG00000017523	DROSHA	99	96.143	Panthera_tigris_altaica
ENSRNOG00000013451	Drosha	100	96.288	ENSPTRG00000016762	DROSHA	99	96.288	Pan_troglodytes
ENSRNOG00000013451	Drosha	100	94.557	ENSPANG00000003027	DROSHA	99	93.348	Papio_anubis
ENSRNOG00000013451	Drosha	99	75.344	ENSPKIG00000011514	drosha	98	76.708	Paramormyrops_kingsleyae
ENSRNOG00000013451	Drosha	100	96.215	ENSPEMG00000000607	Drosha	100	95.997	Peromyscus_maniculatus_bairdii
ENSRNOG00000013451	Drosha	99	84.938	ENSPCIG00000006010	DROSHA	99	85.301	Phascolarctos_cinereus
ENSRNOG00000013451	Drosha	84	79.281	ENSPREG00000022302	drosha	89	79.231	Poecilia_reticulata
ENSRNOG00000013451	Drosha	100	96.215	ENSPPYG00000015370	DROSHA	99	96.215	Pongo_abelii
ENSRNOG00000013451	Drosha	100	80.640	ENSPCAG00000007190	DROSHA	100	80.568	Procavia_capensis
ENSRNOG00000013451	Drosha	100	92.795	ENSPCOG00000028511	DROSHA	100	94.292	Propithecus_coquereli
ENSRNOG00000013451	Drosha	100	91.849	ENSPVAG00000013167	DROSHA	100	91.849	Pteropus_vampyrus
ENSRNOG00000013451	Drosha	97	73.881	ENSPNYG00000000398	drosha	95	88.866	Pundamilia_nyererei
ENSRNOG00000013451	Drosha	78	92.133	ENSPNAG00000011876	drosha	85	87.622	Pygocentrus_nattereri
ENSRNOG00000013451	Drosha	100	94.764	ENSRBIG00000032786	DROSHA	100	94.088	Rhinopithecus_bieti
ENSRNOG00000013451	Drosha	100	96.143	ENSRROG00000028199	DROSHA	99	96.143	Rhinopithecus_roxellana
ENSRNOG00000013451	Drosha	100	95.560	ENSSBOG00000024008	DROSHA	100	96.534	Saimiri_boliviensis_boliviensis
ENSRNOG00000013451	Drosha	98	83.916	ENSSHAG00000015198	DROSHA	93	96.166	Sarcophilus_harrisii
ENSRNOG00000013451	Drosha	91	76.728	ENSSFOG00015009776	drosha	92	79.336	Scleropages_formosus
ENSRNOG00000013451	Drosha	98	71.051	ENSSMAG00000008069	drosha	88	77.065	Scophthalmus_maximus
ENSRNOG00000013451	Drosha	85	78.881	ENSSDUG00000010944	drosha	95	90.994	Seriola_dumerili
ENSRNOG00000013451	Drosha	85	79.097	ENSSLDG00000025271	drosha	95	90.890	Seriola_lalandi_dorsalis
ENSRNOG00000013451	Drosha	72	74.592	ENSSARG00000004436	-	72	74.592	Sorex_araneus
ENSRNOG00000013451	Drosha	99	80.521	ENSSPUG00000006902	DROSHA	100	80.521	Sphenodon_punctatus
ENSRNOG00000013451	Drosha	100	93.450	ENSSSCG00000016809	DROSHA	100	93.500	Sus_scrofa
ENSRNOG00000013451	Drosha	99	84.593	ENSTGUG00000001955	DROSHA	100	84.218	Taeniopygia_guttata
ENSRNOG00000013451	Drosha	64	89.217	ENSTRUG00000017778	drosha	84	77.391	Takifugu_rubripes
ENSRNOG00000013451	Drosha	71	90.174	ENSTNIG00000008688	drosha	94	90.309	Tetraodon_nigroviridis
ENSRNOG00000013451	Drosha	97	85.500	ENSTBEG00000000537	DROSHA	96	88.749	Tupaia_belangeri
ENSRNOG00000013451	Drosha	100	95.051	ENSTTRG00000004210	DROSHA	100	95.051	Tursiops_truncatus
ENSRNOG00000013451	Drosha	100	93.668	ENSUAMG00000025257	DROSHA	99	93.668	Ursus_americanus
ENSRNOG00000013451	Drosha	100	90.850	ENSUMAG00000014097	DROSHA	100	95.821	Ursus_maritimus
ENSRNOG00000013451	Drosha	81	91.689	ENSVPAG00000011260	DROSHA	100	91.689	Vicugna_pacos
ENSRNOG00000013451	Drosha	100	96.288	ENSVVUG00000022212	DROSHA	99	99.125	Vulpes_vulpes
ENSRNOG00000013451	Drosha	87	79.421	ENSXETG00000016701	drosha	89	78.612	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001530	lipopolysaccharide binding	-	IEA	Function
GO:0001530	lipopolysaccharide binding	-	ISO	Function
GO:0003674	molecular_function	-	ND	Function
GO:0003725	double-stranded RNA binding	21873635.	IBA	Function
GO:0004521	endoribonuclease activity	-	ISO	Function
GO:0004525	ribonuclease III activity	21873635.	IBA	Function
GO:0004525	ribonuclease III activity	-	ISO	Function
GO:0005575	cellular_component	-	ND	Component
GO:0005634	nucleus	21873635.	IBA	Component
GO:0006396	RNA processing	21873635.	IBA	Process
GO:0008150	biological_process	-	ND	Process
GO:0010468	regulation of gene expression	-	ISO	Process
GO:0010586	miRNA metabolic process	-	IEA	Process
GO:0010586	miRNA metabolic process	-	ISO	Process
GO:0010628	positive regulation of gene expression	-	IEA	Process
GO:0010628	positive regulation of gene expression	-	ISO	Process
GO:0014069	postsynaptic density	-	IEA	Component
GO:0014069	postsynaptic density	-	ISO	Component
GO:0016075	rRNA catabolic process	-	IEA	Process
GO:0017151	DEAD/H-box RNA helicase binding	-	IEA	Function
GO:0017151	DEAD/H-box RNA helicase binding	-	ISO	Function
GO:0030422	production of siRNA involved in RNA interference	21873635.	IBA	Process
GO:0031053	primary miRNA processing	21873635.	IBA	Process
GO:0031053	primary miRNA processing	-	ISO	Process
GO:0031054	pre-miRNA processing	21873635.	IBA	Process
GO:0031054	pre-miRNA processing	-	ISO	Process
GO:0042803	protein homodimerization activity	-	IEA	Function
GO:0042803	protein homodimerization activity	-	ISO	Function
GO:0045589	regulation of regulatory T cell differentiation	-	IEA	Process
GO:0045589	regulation of regulatory T cell differentiation	-	ISO	Process
GO:0046332	SMAD binding	-	ISO	Function
GO:0050727	regulation of inflammatory response	-	IEA	Process
GO:0050727	regulation of inflammatory response	-	ISO	Process
GO:0050829	defense response to Gram-negative bacterium	-	IEA	Process
GO:0050829	defense response to Gram-negative bacterium	-	ISO	Process
GO:0050830	defense response to Gram-positive bacterium	-	IEA	Process
GO:0050830	defense response to Gram-positive bacterium	-	ISO	Process
GO:0070412	R-SMAD binding	-	IEA	Function
GO:0070412	R-SMAD binding	-	ISO	Function
GO:0070877	microprocessor complex	-	IEA	Component
GO:0070877	microprocessor complex	-	ISO	Component
GO:0070878	primary miRNA binding	-	IEA	Function
GO:0070878	primary miRNA binding	-	ISO	Function
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	-	IEA	Process
GO:2000628	regulation of miRNA metabolic process	-	IEA	Process
GO:2000628	regulation of miRNA metabolic process	-	ISO	Process