EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSRNOG00000015440 (Gene tree)
Gene ID: 290805
Gene Symbol: Wrn
Alias: LOC290805|RGD1564788
Full Name: Werner syndrome RecQ like helicase
Gene Type: protein_coding
Species: Rattus_norvegicus
Status: putative
Strand: Plus strand
Length: 131615 bases
Position: chr16:62483761-62615375
Accession: 1564788
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSRNOP00000055596	HRDC	PF00570.23	1.6e-13	1	1
ENSRNOP00000055596	DEAD	PF00270.29	1.5e-15	1	1
ENSRNOP00000055596	DNA_pol_A_exo1	PF01612.20	8.1e-35	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSRNOT00000058805	-	4618	XM_006253254	ENSRNOP00000055596	1400 (aa)	XP_006222319	F1LTH9

Gene Model

Click here to download ENSRNOG00000015440's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSRNOG00000015440's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSRNOG00000015440	Wrn	100	69.156	ENSG00000165392	WRN	99	69.225	Homo_sapiens
ENSRNOG00000015440	Wrn	81	69.130	ENSAMEG00000000475	-	97	68.826	Ailuropoda_melanoleuca
ENSRNOG00000015440	Wrn	93	55.900	ENSAPLG00000001616	WRN	92	55.816	Anas_platyrhynchos
ENSRNOG00000015440	Wrn	94	50.896	ENSACAG00000003109	WRN	100	50.970	Anolis_carolinensis
ENSRNOG00000015440	Wrn	100	66.923	ENSANAG00000032806	WRN	98	70.393	Aotus_nancymaae
ENSRNOG00000015440	Wrn	94	48.679	ENSAMXG00000010066	wrn	89	48.755	Astyanax_mexicanus
ENSRNOG00000015440	Wrn	99	68.143	ENSBTAG00000021592	WRN	99	67.857	Bos_taurus
ENSRNOG00000015440	Wrn	57	32.754	WBGene00006944	wrn-1	73	32.754	Caenorhabditis_elegans
ENSRNOG00000015440	Wrn	100	69.274	ENSCJAG00000012511	WRN	99	69.274	Callithrix_jacchus
ENSRNOG00000015440	Wrn	100	70.468	ENSCAFG00000006410	WRN	96	70.468	Canis_familiaris
ENSRNOG00000015440	Wrn	100	68.914	ENSCAFG00020001236	WRN	99	68.914	Canis_lupus_dingo
ENSRNOG00000015440	Wrn	99	67.477	ENSCHIG00000014991	WRN	99	67.262	Capra_hircus
ENSRNOG00000015440	Wrn	99	70.839	ENSTSYG00000012689	WRN	99	70.768	Carlito_syrichta
ENSRNOG00000015440	Wrn	86	80.159	ENSCAPG00000016803	WRN	98	64.497	Cavia_aperea
ENSRNOG00000015440	Wrn	99	68.737	ENSCPOG00000002943	WRN	99	68.737	Cavia_porcellus
ENSRNOG00000015440	Wrn	100	69.881	ENSCCAG00000023793	WRN	99	69.881	Cebus_capucinus
ENSRNOG00000015440	Wrn	99	70.706	ENSCATG00000040557	WRN	99	72.018	Cercocebus_atys
ENSRNOG00000015440	Wrn	96	73.407	ENSCLAG00000000817	WRN	99	70.068	Chinchilla_lanigera
ENSRNOG00000015440	Wrn	96	70.584	ENSCSAG00000015810	WRN	99	70.448	Chlorocebus_sabaeus
ENSRNOG00000015440	Wrn	71	85.083	ENSCHOG00000008966	WRN	74	85.083	Choloepus_hoffmanni
ENSRNOG00000015440	Wrn	96	57.111	ENSCPBG00000013421	WRN	91	57.300	Chrysemys_picta_bellii
ENSRNOG00000015440	Wrn	74	36.421	ENSCING00000002232	-	86	36.421	Ciona_intestinalis
ENSRNOG00000015440	Wrn	100	69.811	ENSCANG00000037137	WRN	99	69.811	Colobus_angolensis_palliatus
ENSRNOG00000015440	Wrn	100	82.953	ENSCGRG00001016491	Wrn	100	83.310	Cricetulus_griseus_chok1gshd
ENSRNOG00000015440	Wrn	83	82.297	ENSCGRG00000016821	Wrn	100	82.729	Cricetulus_griseus_crigri
ENSRNOG00000015440	Wrn	94	47.416	ENSDARG00000098211	wrn	90	47.754	Danio_rerio
ENSRNOG00000015440	Wrn	95	65.898	ENSDNOG00000008481	WRN	100	65.898	Dasypus_novemcinctus
ENSRNOG00000015440	Wrn	100	68.944	ENSDORG00000002696	Wrn	100	69.220	Dipodomys_ordii
ENSRNOG00000015440	Wrn	79	80.861	ENSETEG00000019854	WRN	79	80.861	Echinops_telfairi
ENSRNOG00000015440	Wrn	97	65.889	ENSEASG00005016813	WRN	98	77.401	Equus_asinus_asinus
ENSRNOG00000015440	Wrn	100	67.472	ENSECAG00000000110	WRN	99	67.472	Equus_caballus
ENSRNOG00000015440	Wrn	82	64.516	ENSEEUG00000004926	WRN	89	64.516	Erinaceus_europaeus
ENSRNOG00000015440	Wrn	94	47.552	ENSELUG00000017817	wrn	96	52.966	Esox_lucius
ENSRNOG00000015440	Wrn	100	65.850	ENSFCAG00000024759	WRN	99	65.850	Felis_catus
ENSRNOG00000015440	Wrn	100	70.706	ENSFDAG00000008637	WRN	99	70.706	Fukomys_damarensis
ENSRNOG00000015440	Wrn	94	55.896	ENSGALG00000040909	WRN	88	56.078	Gallus_gallus
ENSRNOG00000015440	Wrn	97	56.440	ENSGAGG00000022647	WRN	94	56.626	Gopherus_agassizii
ENSRNOG00000015440	Wrn	100	70.534	ENSGGOG00000022154	WRN	99	70.605	Gorilla_gorilla
ENSRNOG00000015440	Wrn	100	72.242	ENSHGLG00000003638	WRN	100	71.815	Heterocephalus_glaber_female
ENSRNOG00000015440	Wrn	95	46.712	ENSIPUG00000002090	wrn	92	46.637	Ictalurus_punctatus
ENSRNOG00000015440	Wrn	100	70.194	ENSSTOG00000013599	WRN	99	70.194	Ictidomys_tridecemlineatus
ENSRNOG00000015440	Wrn	100	70.492	ENSJJAG00000015655	Wrn	100	70.492	Jaculus_jaculus
ENSRNOG00000015440	Wrn	96	48.502	ENSLACG00000001569	-	93	49.001	Latimeria_chalumnae
ENSRNOG00000015440	Wrn	95	51.553	ENSLOCG00000010792	wrn	92	50.885	Lepisosteus_oculatus
ENSRNOG00000015440	Wrn	100	70.177	ENSLAFG00000004434	WRN	100	70.318	Loxodonta_africana
ENSRNOG00000015440	Wrn	99	70.264	ENSMFAG00000043428	WRN	99	70.550	Macaca_fascicularis
ENSRNOG00000015440	Wrn	100	68.973	ENSMMUG00000022655	WRN	99	69.252	Macaca_mulatta
ENSRNOG00000015440	Wrn	100	69.483	ENSMNEG00000032617	WRN	99	69.483	Macaca_nemestrina
ENSRNOG00000015440	Wrn	99	70.919	ENSMLEG00000038296	WRN	99	70.919	Mandrillus_leucophaeus
ENSRNOG00000015440	Wrn	94	56.399	ENSMGAG00000004960	WRN	88	56.580	Meleagris_gallopavo
ENSRNOG00000015440	Wrn	100	83.880	ENSMAUG00000016235	Wrn	100	84.094	Mesocricetus_auratus
ENSRNOG00000015440	Wrn	100	67.112	ENSMICG00000010630	WRN	99	67.112	Microcebus_murinus
ENSRNOG00000015440	Wrn	100	81.941	ENSMOCG00000013972	Wrn	100	81.941	Microtus_ochrogaster
ENSRNOG00000015440	Wrn	99	55.000	ENSMODG00000018997	WRN	99	55.357	Monodelphis_domestica
ENSRNOG00000015440	Wrn	100	86.510	MGP_CAROLIEiJ_G0030961	Wrn	100	86.510	Mus_caroli
ENSRNOG00000015440	Wrn	100	86.652	ENSMUSG00000031583	Wrn	100	86.652	Mus_musculus
ENSRNOG00000015440	Wrn	100	86.795	MGP_PahariEiJ_G0021430	Wrn	100	86.795	Mus_pahari
ENSRNOG00000015440	Wrn	100	86.438	MGP_SPRETEiJ_G0032079	Wrn	100	86.438	Mus_spretus
ENSRNOG00000015440	Wrn	100	68.253	ENSMPUG00000010201	WRN	99	68.537	Mustela_putorius_furo
ENSRNOG00000015440	Wrn	99	69.922	ENSMLUG00000005863	WRN	99	70.207	Myotis_lucifugus
ENSRNOG00000015440	Wrn	99	76.923	ENSNGAG00000018413	Wrn	99	76.923	Nannospalax_galili
ENSRNOG00000015440	Wrn	100	70.134	ENSNLEG00000012006	WRN	99	70.205	Nomascus_leucogenys
ENSRNOG00000015440	Wrn	70	60.435	ENSMEUG00000008271	-	70	60.435	Notamacropus_eugenii
ENSRNOG00000015440	Wrn	88	58.958	ENSOPRG00000001480	WRN	88	58.958	Ochotona_princeps
ENSRNOG00000015440	Wrn	100	71.174	ENSODEG00000004076	WRN	100	71.317	Octodon_degus
ENSRNOG00000015440	Wrn	90	59.509	ENSOANG00000005952	-	94	59.509	Ornithorhynchus_anatinus
ENSRNOG00000015440	Wrn	100	70.842	ENSOCUG00000012620	WRN	90	70.842	Oryctolagus_cuniculus
ENSRNOG00000015440	Wrn	97	68.513	ENSOGAG00000009600	WRN	100	68.586	Otolemur_garnettii
ENSRNOG00000015440	Wrn	99	67.714	ENSOARG00000000163	WRN	99	67.500	Ovis_aries
ENSRNOG00000015440	Wrn	100	70.057	ENSPPAG00000036871	WRN	99	70.128	Pan_paniscus
ENSRNOG00000015440	Wrn	100	68.324	ENSPPRG00000010928	WRN	99	68.279	Panthera_pardus
ENSRNOG00000015440	Wrn	100	68.301	ENSPTIG00000020609	WRN	99	67.994	Panthera_tigris_altaica
ENSRNOG00000015440	Wrn	100	69.759	ENSPTRG00000020145	WRN	99	69.830	Pan_troglodytes
ENSRNOG00000015440	Wrn	99	69.532	ENSPANG00000018594	WRN	99	69.672	Papio_anubis
ENSRNOG00000015440	Wrn	83	59.211	ENSPKIG00000025497	wrn	99	59.211	Paramormyrops_kingsleyae
ENSRNOG00000015440	Wrn	97	56.751	ENSPSIG00000013411	WRN	92	56.895	Pelodiscus_sinensis
ENSRNOG00000015440	Wrn	99	81.571	ENSPEMG00000020615	Wrn	99	83.218	Peromyscus_maniculatus_bairdii
ENSRNOG00000015440	Wrn	94	56.611	ENSPCIG00000020146	WRN	95	56.991	Phascolarctos_cinereus
ENSRNOG00000015440	Wrn	100	68.876	ENSPPYG00000018494	WRN	99	68.876	Pongo_abelii
ENSRNOG00000015440	Wrn	90	70.487	ENSPCAG00000013763	WRN	88	70.487	Procavia_capensis
ENSRNOG00000015440	Wrn	78	58.075	ENSPCOG00000012938	WRN	96	58.075	Propithecus_coquereli
ENSRNOG00000015440	Wrn	93	67.822	ENSPVAG00000012909	WRN	91	67.822	Pteropus_vampyrus
ENSRNOG00000015440	Wrn	95	47.619	ENSPNAG00000021848	wrn	89	47.771	Pygocentrus_nattereri
ENSRNOG00000015440	Wrn	100	69.922	ENSRBIG00000031825	WRN	99	71.082	Rhinopithecus_bieti
ENSRNOG00000015440	Wrn	100	69.602	ENSRROG00000045381	WRN	99	69.602	Rhinopithecus_roxellana
ENSRNOG00000015440	Wrn	100	69.510	ENSSBOG00000027238	WRN	99	69.441	Saimiri_boliviensis_boliviensis
ENSRNOG00000015440	Wrn	100	56.108	ENSSHAG00000005577	WRN	100	56.250	Sarcophilus_harrisii
ENSRNOG00000015440	Wrn	94	49.437	ENSSFOG00015006123	wrn	94	49.512	Scleropages_formosus
ENSRNOG00000015440	Wrn	73	64.502	ENSSARG00000006157	WRN	87	64.502	Sorex_araneus
ENSRNOG00000015440	Wrn	97	71.733	ENSSSCG00000015840	WRN	99	71.733	Sus_scrofa
ENSRNOG00000015440	Wrn	72	56.280	ENSTGUG00000001765	WRN	99	56.526	Taeniopygia_guttata
ENSRNOG00000015440	Wrn	78	56.005	ENSTBEG00000012702	-	78	56.005	Tupaia_belangeri
ENSRNOG00000015440	Wrn	100	64.982	ENSTTRG00000012302	WRN	99	64.982	Tursiops_truncatus
ENSRNOG00000015440	Wrn	100	66.406	ENSUAMG00000021324	WRN	99	66.358	Ursus_americanus
ENSRNOG00000015440	Wrn	85	66.667	ENSUMAG00000007159	WRN	97	66.500	Ursus_maritimus
ENSRNOG00000015440	Wrn	100	64.755	ENSVPAG00000011004	WRN	99	64.755	Vicugna_pacos
ENSRNOG00000015440	Wrn	100	66.942	ENSVVUG00000019867	WRN	99	66.942	Vulpes_vulpes
ENSRNOG00000015440	Wrn	98	53.017	ENSXETG00000018302	wrn	99	54.342	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000287	magnesium ion binding	21873635.	IBA	Function
GO:0000287	magnesium ion binding	-	ISO	Function
GO:0000400	four-way junction DNA binding	21873635.	IBA	Function
GO:0000400	four-way junction DNA binding	-	ISO	Function
GO:0000403	Y-form DNA binding	21873635.	IBA	Function
GO:0000403	Y-form DNA binding	-	ISO	Function
GO:0000405	bubble DNA binding	21873635.	IBA	Function
GO:0000405	bubble DNA binding	-	ISO	Function
GO:0000723	telomere maintenance	-	ISO	Process
GO:0000724	double-strand break repair via homologous recombination	21873635.	IBA	Process
GO:0000731	DNA synthesis involved in DNA repair	21873635.	IBA	Process
GO:0000731	DNA synthesis involved in DNA repair	-	ISO	Process
GO:0000781	chromosome, telomeric region	21873635.	IBA	Component
GO:0000781	chromosome, telomeric region	-	ISO	Component
GO:0001302	replicative cell aging	21873635.	IBA	Process
GO:0001302	replicative cell aging	-	ISO	Process
GO:0003677	DNA binding	21873635.	IBA	Function
GO:0003677	DNA binding	-	ISO	Function
GO:0003678	DNA helicase activity	-	ISO	Function
GO:0003682	chromatin binding	21873635.	IBA	Function
GO:0003682	chromatin binding	19737542.	IDA	Function
GO:0004003	ATP-dependent DNA helicase activity	-	ISO	Function
GO:0004386	helicase activity	-	ISO	Function
GO:0004527	exonuclease activity	-	ISO	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	ISO	Component
GO:0005654	nucleoplasm	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	ISO	Component
GO:0005657	replication fork	21873635.	IBA	Component
GO:0005657	replication fork	-	ISO	Component
GO:0005662	DNA replication factor A complex	21873635.	IBA	Component
GO:0005694	chromosome	21873635.	IBA	Component
GO:0005730	nucleolus	-	IEA	Component
GO:0005730	nucleolus	-	ISO	Component
GO:0005730	nucleolus	-	ISO	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005813	centrosome	21873635.	IBA	Component
GO:0005813	centrosome	-	ISO	Component
GO:0006259	DNA metabolic process	-	ISO	Process
GO:0006260	DNA replication	-	ISO	Process
GO:0006281	DNA repair	21873635.	IBA	Process
GO:0006284	base-excision repair	21873635.	IBA	Process
GO:0006284	base-excision repair	-	ISO	Process
GO:0006302	double-strand break repair	-	ISO	Process
GO:0006310	DNA recombination	21873635.	IBA	Process
GO:0006974	cellular response to DNA damage stimulus	-	ISO	Process
GO:0006979	response to oxidative stress	21873635.	IBA	Process
GO:0006979	response to oxidative stress	-	ISO	Process
GO:0007420	brain development	12020873.	IEP	Process
GO:0007569	cell aging	21873635.	IBA	Process
GO:0007569	cell aging	-	ISO	Process
GO:0008340	determination of adult lifespan	21873635.	IBA	Process
GO:0008408	3'-5' exonuclease activity	21873635.	IBA	Function
GO:0008408	3'-5' exonuclease activity	-	ISO	Function
GO:0009267	cellular response to starvation	21873635.	IBA	Process
GO:0009267	cellular response to starvation	-	ISO	Process
GO:0009378	four-way junction helicase activity	21873635.	IBA	Function
GO:0009378	four-way junction helicase activity	-	ISO	Function
GO:0010225	response to UV-C	21873635.	IBA	Process
GO:0010225	response to UV-C	-	ISO	Process
GO:0010259	multicellular organism aging	21873635.	IBA	Process
GO:0010259	multicellular organism aging	-	ISO	Process
GO:0016607	nuclear speck	-	IEA	Component
GO:0016607	nuclear speck	-	ISO	Component
GO:0016887	ATPase activity	-	ISO	Function
GO:0030145	manganese ion binding	21873635.	IBA	Function
GO:0030145	manganese ion binding	-	ISO	Function
GO:0031297	replication fork processing	21873635.	IBA	Process
GO:0031297	replication fork processing	-	ISO	Process
GO:0032405	MutLalpha complex binding	-	IEA	Function
GO:0032405	MutLalpha complex binding	-	ISO	Function
GO:0032508	DNA duplex unwinding	21873635.	IBA	Process
GO:0032508	DNA duplex unwinding	-	ISO	Process
GO:0035861	site of double-strand break	21873635.	IBA	Component
GO:0040009	regulation of growth rate	-	IEA	Process
GO:0040009	regulation of growth rate	-	ISO	Process
GO:0042803	protein homodimerization activity	21873635.	IBA	Function
GO:0042803	protein homodimerization activity	-	ISO	Function
GO:0042981	regulation of apoptotic process	21873635.	IBA	Process
GO:0042981	regulation of apoptotic process	-	ISO	Process
GO:0043005	neuron projection	12020873.	IDA	Component
GO:0043138	3'-5' DNA helicase activity	-	ISO	Function
GO:0043140	ATP-dependent 3'-5' DNA helicase activity	21873635.	IBA	Function
GO:0044806	G-quadruplex DNA unwinding	21873635.	IBA	Process
GO:0044806	G-quadruplex DNA unwinding	-	ISO	Process
GO:0044877	protein-containing complex binding	21873635.	IBA	Function
GO:0044877	protein-containing complex binding	-	ISO	Function
GO:0051345	positive regulation of hydrolase activity	21873635.	IBA	Process
GO:0051345	positive regulation of hydrolase activity	-	ISO	Process
GO:0051880	G-quadruplex DNA binding	-	IEA	Function
GO:0051880	G-quadruplex DNA binding	-	ISO	Function
GO:0061749	forked DNA-dependent helicase activity	21873635.	IBA	Function
GO:0061749	forked DNA-dependent helicase activity	-	ISO	Function
GO:0061820	telomeric D-loop disassembly	21873635.	IBA	Process
GO:0061820	telomeric D-loop disassembly	-	ISO	Process
GO:0061821	telomeric D-loop binding	21873635.	IBA	Function
GO:0061821	telomeric D-loop binding	-	ISO	Function
GO:0070337	3'-flap-structured DNA binding	21873635.	IBA	Function
GO:0070337	3'-flap-structured DNA binding	-	ISO	Function
GO:0071480	cellular response to gamma radiation	21873635.	IBA	Process
GO:0071480	cellular response to gamma radiation	-	ISO	Process
GO:0090305	nucleic acid phosphodiester bond hydrolysis	-	IEA	Process
GO:0098530	positive regulation of strand invasion	21873635.	IBA	Process
GO:0098530	positive regulation of strand invasion	-	ISO	Process
GO:1902570	protein localization to nucleolus	-	IEA	Process
GO:1902570	protein localization to nucleolus	-	ISO	Process
GO:1905773	8-hydroxy-2'-deoxyguanosine DNA binding	21873635.	IBA	Function
GO:1905773	8-hydroxy-2'-deoxyguanosine DNA binding	-	ISO	Function