EuRBPDB

Description

RBDs

RBPome

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: FBgn0015218 (Gene tree)
Gene ID: 45525
Gene Symbol: eIF4E1
Alias: -
Full Name: eukaryotic translation initiation factor 4E1
Gene Type: protein_coding
Species: Drosophila_melanogaster
Status: confidence
Strand: Minus strand
Length: 2843 bases
Position: chr3L:9399618-9402460
Accession: FBgn0015218
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
FBpp0076216	IF4E	PF01652.18	6e-56	1	1
FBpp0076215	IF4E	PF01652.18	6.5e-56	1	1
FBpp0076217	IF4E	PF01652.18	6.5e-56	1	1
FBpp0076218	IF4E	PF01652.18	6.5e-56	1	1
FBpp0076219	IF4E	PF01652.18	6.5e-56	1	1
FBpp0076220	IF4E	PF01652.18	6.5e-56	1	1
FBpp0076221	IF4E	PF01652.18	6.5e-56	1	1
FBpp0306016	IF4E	PF01652.18	6.5e-56	1	1
FBpp0306017	IF4E	PF01652.18	6.5e-56	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27378189	Global changes of the RNA bound proteome during the maternal-to-zygotic transition in Drosophila	IC & embryos.MZT	2016 Jul 5	Sysoev VO	DOI: 10.1038/ncomms12128
27197210	The mRNA-bound proteome of the early fly embryo	IC & embryos	2016 Apr 28	Wessels HH	DOI: 10.1101/gr.200386.115

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
FBtr0076487	-	1484	-	FBpp0076215	259 (aa)	-	P48598
FBtr0076488	-	1156	-	FBpp0076216	248 (aa)	-	P48598-2
FBtr0076489	-	1723	-	FBpp0076217	259 (aa)	-	P48598
FBtr0333884	-	1492	-	FBpp0306016	259 (aa)	-	P48598
FBtr0333885	-	1793	-	FBpp0306017	259 (aa)	-	P48598
FBtr0076493	-	1452	-	FBpp0076221	259 (aa)	-	P48598
FBtr0076492	-	1524	-	FBpp0076220	259 (aa)	-	P48598
FBtr0076491	-	1358	-	FBpp0076219	259 (aa)	-	P48598
FBtr0076490	-	1430	-	FBpp0076218	259 (aa)	-	P48598

Gene Model

Click here to download FBgn0015218's gene model file

Protein-Protein Interaction (PPI)

Clik here to download FBgn0015218's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
FBgn0015218	eIF4E1	50	32.031	FBgn0053100	eIF4EHP	63	33.333
FBgn0015218	eIF4E1	90	53.846	FBgn0035823	eIF4E5	99	53.846
FBgn0015218	eIF4E1	55	60.584	FBgn0039622	eIF4E6	79	60.584
FBgn0015218	eIF4E1	73	58.333	FBgn0265089	eIF4E3	73	58.333
FBgn0015218	eIF4E1	73	73.889	FBgn0035709	eIF4E4	78	73.889

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
FBgn0015218	eIF4E1	66	43.373	YOL139C	CDC33	77	43.373	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000278	mitotic cell cycle	11290718.18463163.	HMP	Process
GO:0000339	RNA cap binding	8663200.	IDA	Function
GO:0000339	RNA cap binding	10908586.	ISS	Function
GO:0000340	RNA 7-methylguanosine cap binding	21873635.	IBA	Function
GO:0000340	RNA 7-methylguanosine cap binding	8027064.15804566.15882623.22833128.	IDA	Function
GO:0000932	P-body	17595295.	IDA	Component
GO:0001558	regulation of cell growth	11865045.	IMP	Process
GO:0002191	cap-dependent translational initiation	25416947.	IMP	Process
GO:0003743	translation initiation factor activity	21873635.	IBA	Function
GO:0003743	translation initiation factor activity	8663200.	IDA	Function
GO:0003743	translation initiation factor activity	15804566.	IGI	Function
GO:0003743	translation initiation factor activity	7742371.10908586.	ISS	Function
GO:0005515	protein binding	15804566.18780789.	IPI	Function
GO:0005737	cytoplasm	26896675.	HDA	Component
GO:0005737	cytoplasm	10890448.20869429.	IDA	Component
GO:0005829	cytosol	7742371.10908586.	ISS	Component
GO:0005845	mRNA cap binding complex	-	ISS	Component
GO:0006325	chromatin organization	11290718.	HMP	Process
GO:0006412	translation	8027064.	IDA	Process
GO:0006412	translation	7742371.	ISS	Process
GO:0006413	translational initiation	8663200.	IDA	Process
GO:0006413	translational initiation	15804566.	IGI	Process
GO:0007060	male meiosis chromosome segregation	25849588.	IMP	Process
GO:0007076	mitotic chromosome condensation	11290718.	HMP	Process
GO:0007112	male meiosis cytokinesis	25849588.	IMP	Process
GO:0010032	meiotic chromosome condensation	25849588.	IMP	Process
GO:0016070	RNA metabolic process	8663200.	IDA	Process
GO:0016281	eukaryotic translation initiation factor 4F complex	21873635.	IBA	Component
GO:0016281	eukaryotic translation initiation factor 4F complex	8027064.	IDA	Component
GO:0016281	eukaryotic translation initiation factor 4F complex	15804566.	IPI	Component
GO:0016281	eukaryotic translation initiation factor 4F complex	10908586.	ISS	Component
GO:0016281	eukaryotic translation initiation factor 4F complex	9065696.	NAS	Component
GO:0016321	female meiosis chromosome segregation	11290718.	HMP	Process
GO:0030307	positive regulation of cell growth	12559758.	TAS	Process
GO:0031370	eukaryotic initiation factor 4G binding	9578457.15804566.	IPI	Function
GO:0031594	neuromuscular junction	15541314.	IDA	Component
GO:0045995	regulation of embryonic development	15804566.	IMP	Process
GO:0048136	male germ-line cyst formation	25849588.	IMP	Process
GO:0048137	spermatocyte division	25849588.	IMP	Process
GO:0048515	spermatid differentiation	25849588.	IMP	Process
GO:0071598	neuronal ribonucleoprotein granule	17178403.	IDA	Component
GO:0097482	muscle cell postsynaptic specialization	15541314.	IDA	Component
GO:1990124	messenger ribonucleoprotein complex	17178403.	IDA	Component