EuRBPDB

Description

RBDs

RBPome

Transcripts

Gene Model

PPI

Paralogs

Gene Ontology

Description

Ensembl ID: FBgn0034246 (Gene tree)
Gene ID: 36993
Gene Symbol: Dcr-2
Alias: -
Full Name: Dicer-2
Gene Type: protein_coding
Species: Drosophila_melanogaster
Status: confidence
Strand: Minus strand
Length: 6547 bases
Position: chr2R:17574979-17581525
Accession: FBgn0034246
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
FBpp0309192	Ribonuclease_3	PF00636.26	6.3e-48	1	2
FBpp0309192	Ribonuclease_3	PF00636.26	6.3e-48	2	2
FBpp0086061	Ribonuclease_3	PF00636.26	6.5e-48	1	2
FBpp0086061	Ribonuclease_3	PF00636.26	6.5e-48	2	2
FBpp0309192	PAZ	PF02170.22	1.6e-22	1	1
FBpp0086061	PAZ	PF02170.22	1.6e-22	1	1
FBpp0309192	dsrm	PF00035.26	2.3e-16	1	1
FBpp0086061	dsrm	PF00035.26	2.3e-16	1	1
FBpp0309192	Ribonucleas_3_3	PF14622.6	1.2e-23	1	1
FBpp0086061	Ribonucleas_3_3	PF14622.6	1.2e-23	1	1
FBpp0309192	ResIII	PF04851.15	1.3e-13	1	1
FBpp0086061	ResIII	PF04851.15	1.3e-13	1	1
FBpp0086061	DEAD	PF00270.29	5.7e-14	1	1
FBpp0309192	DEAD	PF00270.29	5.7e-14	1	1
FBpp0086061	Dicer_dimer	PF03368.14	2.8e-21	1	1
FBpp0309192	Dicer_dimer	PF03368.14	2.8e-21	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27197210	The mRNA-bound proteome of the early fly embryo	IC & embryos	2016 Apr 28	Wessels HH	DOI: 10.1101/gr.200386.115

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
FBtr0340217	-	5681	-	FBpp0309192	1721 (aa)	-	A0A0B4LFK8
FBtr0086904	-	5684	-	FBpp0086061	1722 (aa)	-	A1ZAW0

Gene Model

Click here to download FBgn0034246's gene model file

Protein-Protein Interaction (PPI)

Clik here to download FBgn0034246's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
FBgn0034246	Dcr-2	67	32.860	FBgn0039016	Dcr-1	52	32.682

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002230	positive regulation of defense response to virus by host	19763182.	IMP	Process
GO:0003725	double-stranded RNA binding	10908586.	ISS	Function
GO:0003730	mRNA 3'-UTR binding	26601278.	IDA	Function
GO:0004386	helicase activity	10908586.	ISS	Function
GO:0004525	ribonuclease III activity	21873635.	IBA	Function
GO:0004525	ribonuclease III activity	28416567.	IDA	Function
GO:0004530	deoxyribonuclease I activity	21873635.	IBA	Function
GO:0005515	protein binding	19632183.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	16530043.26257286.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	16530043.26257286.	IDA	Component
GO:0006309	apoptotic DNA fragmentation	21873635.	IBA	Process
GO:0006342	chromatin silencing	16530043.	IMP	Process
GO:0007626	locomotory behavior	21165178.	IMP	Process
GO:0009047	dosage compensation by hyperactivation of X chromosome	22554892.	IGI	Process
GO:0009597	detection of virus	18953338.	IMP	Process
GO:0016246	RNA interference	11201747.	IDA	Process
GO:0016246	RNA interference	15066283.	IMP	Process
GO:0016442	RISC complex	21873635.	IBA	Component
GO:0016442	RISC complex	19661431.	IDA	Component
GO:0016443	bidentate ribonuclease III activity	18454937.	IMP	Function
GO:0016887	ATPase activity	21419681.	IDA	Function
GO:0030422	production of siRNA involved in RNA interference	21873635.	IBA	Process
GO:0030422	production of siRNA involved in RNA interference	14512631.28416567.	IDA	Process
GO:0030422	production of siRNA involved in RNA interference	15066283.16809489.18403677.18454937.18463630.28416567.	IMP	Process
GO:0030422	production of siRNA involved in RNA interference	15211354.	TAS	Process
GO:0030423	targeting of mRNA for destruction involved in RNA interference	15066283.18454937.	IMP	Process
GO:0031054	pre-miRNA processing	21419681.	IDA	Process
GO:0033227	dsRNA transport	16862146.	IMP	Process
GO:0035087	siRNA loading onto RISC involved in RNA interference	15066283.	IMP	Process
GO:0035197	siRNA binding	21300896.	IDA	Function
GO:0045089	positive regulation of innate immune response	26601278.	IMP	Process
GO:0045752	positive regulation of Toll signaling pathway	26601278.	IMP	Process
GO:0051607	defense response to virus	16554838.16556799.20978209.21957285.23255357.25770426.	IMP	Process
GO:0070578	RISC-loading complex	29775584.	IGI	Component
GO:0070578	RISC-loading complex	28416567.	IPI	Component
GO:0070868	heterochromatin organization involved in chromatin silencing	19948966.	IMP	Process
GO:0070922	small RNA loading onto RISC	28416567.	IDA	Process
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	18454937.	IMP	Process
GO:0098586	cellular response to virus	25770426.	IMP	Process