EuRBPDB

Description

RBDs

RBPome

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: FBgn0039016 (Gene tree)
Gene ID: 42693
Gene Symbol: Dcr-1
Alias: -
Full Name: Dicer-1
Gene Type: protein_coding
Species: Drosophila_melanogaster
Status: confidence
Strand: Minus strand
Length: 7085 bases
Position: chr3R:22734007-22741091
Accession: FBgn0039016
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
FBpp0083717	Ribonuclease_3	PF00636.26	8e-61	1	2
FBpp0083717	Ribonuclease_3	PF00636.26	8e-61	2	2
FBpp0083717	PAZ	PF02170.22	2.8e-40	1	1
FBpp0083717	Ribonucleas_3_3	PF14622.6	3.7e-25	1	1
FBpp0083717	Dicer_dimer	PF03368.14	4.2e-25	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27378189	Global changes of the RNA bound proteome during the maternal-to-zygotic transition in Drosophila	IC & embryos.MZT	2016 Jul 5	Sysoev VO	DOI: 10.1038/ncomms12128
27197210	The mRNA-bound proteome of the early fly embryo	IC & embryos	2016 Apr 28	Wessels HH	DOI: 10.1101/gr.200386.115

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
FBtr0084324	-	6913	-	FBpp0083717	2249 (aa)	-	Q9VCU9

Gene Model

Click here to download FBgn0039016's gene model file

Protein-Protein Interaction (PPI)

Clik here to download FBgn0039016's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
FBgn0039016	Dcr-1	52	32.682	FBgn0034246	Dcr-2	67	32.860

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
FBgn0039016	Dcr-1	70	63.918	ENSG00000100697	DICER1	81	63.918	Homo_sapiens
FBgn0039016	Dcr-1	66	63.918	ENSAPOG00000020381	dicer1	78	63.918	Acanthochromis_polyacanthus
FBgn0039016	Dcr-1	68	63.918	ENSAMEG00000006447	DICER1	81	63.918	Ailuropoda_melanoleuca
FBgn0039016	Dcr-1	61	57.062	ENSACIG00000000890	dicer1	74	56.780	Amphilophus_citrinellus
FBgn0039016	Dcr-1	66	63.918	ENSAOCG00000023381	dicer1	77	63.918	Amphiprion_ocellaris
FBgn0039016	Dcr-1	66	63.918	ENSAPEG00000022809	dicer1	77	63.918	Amphiprion_percula
FBgn0039016	Dcr-1	72	63.918	ENSATEG00000014048	dicer1	78	63.918	Anabas_testudineus
FBgn0039016	Dcr-1	68	63.918	ENSAPLG00000012407	DICER1	78	63.918	Anas_platyrhynchos
FBgn0039016	Dcr-1	70	60.577	ENSACAG00000013033	DICER1	78	60.577	Anolis_carolinensis
FBgn0039016	Dcr-1	70	63.918	ENSANAG00000023622	DICER1	81	63.918	Aotus_nancymaae
FBgn0039016	Dcr-1	66	63.918	ENSACLG00000007920	dicer1	77	63.918	Astatotilapia_calliptera
FBgn0039016	Dcr-1	68	56.620	ENSAMXG00000010730	dicer1	80	56.338	Astyanax_mexicanus
FBgn0039016	Dcr-1	73	63.918	ENSBTAG00000012852	DICER1	82	63.918	Bos_taurus
FBgn0039016	Dcr-1	71	45.455	WBGene00000939	dcr-1	82	45.269	Caenorhabditis_elegans
FBgn0039016	Dcr-1	70	63.918	ENSCJAG00000006225	DICER1	81	63.918	Callithrix_jacchus
FBgn0039016	Dcr-1	71	60.577	ENSCAFG00000017701	DICER1	81	60.577	Canis_familiaris
FBgn0039016	Dcr-1	71	60.577	ENSCAFG00020014247	DICER1	81	60.577	Canis_lupus_dingo
FBgn0039016	Dcr-1	70	63.918	ENSCHIG00000015885	DICER1	81	63.918	Capra_hircus
FBgn0039016	Dcr-1	63	55.858	ENSTSYG00000002044	DICER1	75	55.586	Carlito_syrichta
FBgn0039016	Dcr-1	52	60.825	ENSCAPG00000000101	DICER1	64	60.825	Cavia_aperea
FBgn0039016	Dcr-1	68	63.918	ENSCPOG00000004221	DICER1	79	63.918	Cavia_porcellus
FBgn0039016	Dcr-1	71	54.264	ENSCCAG00000027063	DICER1	83	54.264	Cebus_capucinus
FBgn0039016	Dcr-1	70	63.918	ENSCATG00000031403	DICER1	82	63.918	Cercocebus_atys
FBgn0039016	Dcr-1	71	63.918	ENSCLAG00000015000	DICER1	82	63.918	Chinchilla_lanigera
FBgn0039016	Dcr-1	71	54.264	ENSCSAG00000010696	DICER1	83	54.264	Chlorocebus_sabaeus
FBgn0039016	Dcr-1	70	60.577	ENSCPBG00000009859	DICER1	78	60.577	Chrysemys_picta_bellii
FBgn0039016	Dcr-1	73	58.416	ENSCING00000008383	-	85	58.416	Ciona_intestinalis
FBgn0039016	Dcr-1	70	63.918	ENSCANG00000031429	DICER1	82	63.918	Colobus_angolensis_palliatus
FBgn0039016	Dcr-1	68	60.577	ENSCGRG00001008088	Dicer1	78	60.577	Cricetulus_griseus_chok1gshd
FBgn0039016	Dcr-1	68	60.577	ENSCGRG00000012281	Dicer1	78	60.577	Cricetulus_griseus_crigri
FBgn0039016	Dcr-1	66	63.918	ENSCSEG00000017078	dicer1	79	63.918	Cynoglossus_semilaevis
FBgn0039016	Dcr-1	70	58.407	ENSCVAG00000020035	dicer1	80	58.407	Cyprinodon_variegatus
FBgn0039016	Dcr-1	67	63.918	ENSDARG00000001129	dicer1	80	56.620	Danio_rerio
FBgn0039016	Dcr-1	70	63.918	ENSDNOG00000004190	DICER1	81	63.918	Dasypus_novemcinctus
FBgn0039016	Dcr-1	67	63.918	ENSDORG00000006215	Dicer1	78	63.918	Dipodomys_ordii
FBgn0039016	Dcr-1	50	62.557	ENSETEG00000011000	DICER1	64	62.100	Echinops_telfairi
FBgn0039016	Dcr-1	75	63.000	ENSEBUG00000013802	dicer1	82	63.000	Eptatretus_burgeri
FBgn0039016	Dcr-1	70	63.918	ENSEASG00005021485	DICER1	81	63.918	Equus_asinus_asinus
FBgn0039016	Dcr-1	71	63.918	ENSECAG00000006079	DICER1	81	63.918	Equus_caballus
FBgn0039016	Dcr-1	73	63.918	ENSELUG00000024317	dicer1	79	63.918	Esox_lucius
FBgn0039016	Dcr-1	71	63.918	ENSFCAG00000003535	DICER1	83	63.918	Felis_catus
FBgn0039016	Dcr-1	70	54.960	ENSFALG00000002516	DICER1	80	54.692	Ficedula_albicollis
FBgn0039016	Dcr-1	68	63.918	ENSFDAG00000021287	DICER1	82	63.918	Fukomys_damarensis
FBgn0039016	Dcr-1	69	58.407	ENSFHEG00000016839	dicer1	82	58.407	Fundulus_heteroclitus
FBgn0039016	Dcr-1	62	56.583	ENSGMOG00000006057	dicer1	73	56.303	Gadus_morhua
FBgn0039016	Dcr-1	70	63.918	ENSGALG00000010999	DICER1	80	63.918	Gallus_gallus
FBgn0039016	Dcr-1	69	58.407	ENSGAFG00000010728	dicer1	80	58.407	Gambusia_affinis
FBgn0039016	Dcr-1	69	63.918	ENSGACG00000020134	dicer1	79	63.918	Gasterosteus_aculeatus
FBgn0039016	Dcr-1	70	63.918	ENSGGOG00000003760	DICER1	81	63.918	Gorilla_gorilla
FBgn0039016	Dcr-1	66	63.918	ENSHBUG00000018941	dicer1	77	63.918	Haplochromis_burtoni
FBgn0039016	Dcr-1	71	63.918	ENSHGLG00000018124	DICER1	82	63.918	Heterocephalus_glaber_female
FBgn0039016	Dcr-1	71	63.918	ENSHGLG00100010985	DICER1	82	63.918	Heterocephalus_glaber_male
FBgn0039016	Dcr-1	70	61.165	ENSHCOG00000015738	dicer1	79	61.165	Hippocampus_comes
FBgn0039016	Dcr-1	67	62.136	ENSIPUG00000005080	dicer1	81	56.215	Ictalurus_punctatus
FBgn0039016	Dcr-1	71	63.918	ENSSTOG00000022439	DICER1	82	63.918	Ictidomys_tridecemlineatus
FBgn0039016	Dcr-1	68	63.918	ENSJJAG00000010766	Dicer1	78	63.918	Jaculus_jaculus
FBgn0039016	Dcr-1	64	64.651	ENSKMAG00000001429	dicer1	81	64.186	Kryptolebias_marmoratus
FBgn0039016	Dcr-1	68	63.918	ENSLBEG00000008928	dicer1	78	63.918	Labrus_bergylta
FBgn0039016	Dcr-1	69	63.918	ENSLACG00000008302	DICER1	78	63.918	Latimeria_chalumnae
FBgn0039016	Dcr-1	65	63.918	ENSLOCG00000008544	dicer1	74	63.918	Lepisosteus_oculatus
FBgn0039016	Dcr-1	68	54.278	ENSLAFG00000013632	DICER1	83	53.788	Loxodonta_africana
FBgn0039016	Dcr-1	70	63.918	ENSMFAG00000002987	DICER1	82	63.918	Macaca_fascicularis
FBgn0039016	Dcr-1	70	63.918	ENSMMUG00000023305	DICER1	82	63.918	Macaca_mulatta
FBgn0039016	Dcr-1	70	63.918	ENSMNEG00000021073	DICER1	82	63.918	Macaca_nemestrina
FBgn0039016	Dcr-1	67	63.918	ENSMLEG00000034800	DICER1	78	63.918	Mandrillus_leucophaeus
FBgn0039016	Dcr-1	67	63.918	ENSMAMG00000016806	dicer1	77	63.918	Mastacembelus_armatus
FBgn0039016	Dcr-1	66	63.918	ENSMZEG00005016989	dicer1	77	63.918	Maylandia_zebra
FBgn0039016	Dcr-1	70	63.918	ENSMGAG00000013207	DICER1	78	63.918	Meleagris_gallopavo
FBgn0039016	Dcr-1	68	60.577	ENSMAUG00000009936	Dicer1	78	60.577	Mesocricetus_auratus
FBgn0039016	Dcr-1	67	63.918	ENSMICG00000011690	DICER1	81	63.918	Microcebus_murinus
FBgn0039016	Dcr-1	68	60.577	ENSMOCG00000018636	Dicer1	78	60.577	Microtus_ochrogaster
FBgn0039016	Dcr-1	67	63.918	ENSMMOG00000018531	dicer1	79	63.918	Mola_mola
FBgn0039016	Dcr-1	70	63.918	ENSMODG00000012624	DICER1	78	63.918	Monodelphis_domestica
FBgn0039016	Dcr-1	68	63.918	ENSMALG00000009445	dicer1	78	63.918	Monopterus_albus
FBgn0039016	Dcr-1	67	63.918	ENSMUSG00000041415	Dicer1	78	63.918	Mus_musculus
FBgn0039016	Dcr-1	71	63.918	ENSMPUG00000003130	DICER1	82	63.918	Mustela_putorius_furo
FBgn0039016	Dcr-1	68	63.265	ENSMLUG00000003991	DICER1	82	63.265	Myotis_lucifugus
FBgn0039016	Dcr-1	71	63.918	ENSNGAG00000010103	Dicer1	82	63.918	Nannospalax_galili
FBgn0039016	Dcr-1	66	57.062	ENSNBRG00000022306	dicer1	77	56.780	Neolamprologus_brichardi
FBgn0039016	Dcr-1	71	54.264	ENSNLEG00000017309	DICER1	83	54.264	Nomascus_leucogenys
FBgn0039016	Dcr-1	64	63.918	ENSOPRG00000014698	DICER1	72	63.918	Ochotona_princeps
FBgn0039016	Dcr-1	71	63.918	ENSODEG00000008594	DICER1	82	63.918	Octodon_degus
FBgn0039016	Dcr-1	66	63.918	ENSONIG00000010424	dicer1	77	63.918	Oreochromis_niloticus
FBgn0039016	Dcr-1	70	63.918	ENSOANG00000012034	DICER1	78	63.918	Ornithorhynchus_anatinus
FBgn0039016	Dcr-1	66	62.887	ENSOCUG00000010849	DICER1	76	62.887	Oryctolagus_cuniculus
FBgn0039016	Dcr-1	67	63.918	ENSORLG00000011022	dicer1	78	63.918	Oryzias_latipes
FBgn0039016	Dcr-1	67	63.918	ENSORLG00020021795	dicer1	78	63.918	Oryzias_latipes_hni
FBgn0039016	Dcr-1	67	63.918	ENSORLG00015019667	dicer1	78	63.918	Oryzias_latipes_hsok
FBgn0039016	Dcr-1	68	55.899	ENSOMEG00000018679	dicer1	80	56.497	Oryzias_melastigma
FBgn0039016	Dcr-1	64	63.918	ENSOGAG00000010719	DICER1	78	63.918	Otolemur_garnettii
FBgn0039016	Dcr-1	73	63.918	ENSOARG00000015465	DICER1	81	63.918	Ovis_aries
FBgn0039016	Dcr-1	70	63.918	ENSPPAG00000035143	DICER1	81	63.918	Pan_paniscus
FBgn0039016	Dcr-1	71	63.918	ENSPPRG00000001322	DICER1	83	63.918	Panthera_pardus
FBgn0039016	Dcr-1	71	63.918	ENSPTIG00000008215	DICER1	83	63.918	Panthera_tigris_altaica
FBgn0039016	Dcr-1	70	63.918	ENSPTRG00000023484	DICER1	81	63.918	Pan_troglodytes
FBgn0039016	Dcr-1	70	63.918	ENSPANG00000023078	DICER1	82	63.918	Papio_anubis
FBgn0039016	Dcr-1	68	63.918	ENSPKIG00000019962	dicer1	78	63.918	Paramormyrops_kingsleyae
FBgn0039016	Dcr-1	69	63.918	ENSPSIG00000010801	DICER1	78	63.918	Pelodiscus_sinensis
FBgn0039016	Dcr-1	68	63.918	ENSPMGG00000010210	dicer1	80	63.918	Periophthalmus_magnuspinnatus
FBgn0039016	Dcr-1	68	60.577	ENSPEMG00000014125	Dicer1	78	60.577	Peromyscus_maniculatus_bairdii
FBgn0039016	Dcr-1	70	63.918	ENSPCIG00000018004	DICER1	78	63.918	Phascolarctos_cinereus
FBgn0039016	Dcr-1	69	58.407	ENSPFOG00000008531	dicer1	80	58.407	Poecilia_formosa
FBgn0039016	Dcr-1	69	58.407	ENSPLAG00000008539	dicer1	79	58.407	Poecilia_latipinna
FBgn0039016	Dcr-1	70	57.345	ENSPMEG00000014284	dicer1	80	57.062	Poecilia_mexicana
FBgn0039016	Dcr-1	69	58.407	ENSPREG00000012120	dicer1	80	58.407	Poecilia_reticulata
FBgn0039016	Dcr-1	70	63.918	ENSPPYG00000006112	DICER1	81	63.918	Pongo_abelii
FBgn0039016	Dcr-1	51	55.556	ENSPCAG00000010828	DICER1	60	55.556	Procavia_capensis
FBgn0039016	Dcr-1	70	63.918	ENSPCOG00000022909	DICER1	81	63.918	Propithecus_coquereli
FBgn0039016	Dcr-1	57	63.918	ENSPVAG00000004811	DICER1	68	63.918	Pteropus_vampyrus
FBgn0039016	Dcr-1	66	63.918	ENSPNYG00000017939	dicer1	77	63.918	Pundamilia_nyererei
FBgn0039016	Dcr-1	67	63.918	ENSPNAG00000001012	dicer1	78	55.710	Pygocentrus_nattereri
FBgn0039016	Dcr-1	68	60.952	ENSRNOG00000010711	Dicer1	78	60.952	Rattus_norvegicus
FBgn0039016	Dcr-1	71	54.264	ENSRBIG00000020932	DICER1	83	54.264	Rhinopithecus_bieti
FBgn0039016	Dcr-1	70	63.918	ENSRROG00000031891	DICER1	82	63.918	Rhinopithecus_roxellana
FBgn0039016	Dcr-1	70	63.918	ENSSBOG00000028660	DICER1	81	63.918	Saimiri_boliviensis_boliviensis
FBgn0039016	Dcr-1	70	63.918	ENSSHAG00000012077	DICER1	78	63.918	Sarcophilus_harrisii
FBgn0039016	Dcr-1	68	63.918	ENSSFOG00015010804	dicer1	85	63.918	Scleropages_formosus
FBgn0039016	Dcr-1	66	63.918	ENSSMAG00000015520	dicer1	78	63.918	Scophthalmus_maximus
FBgn0039016	Dcr-1	67	63.918	ENSSDUG00000021652	dicer1	77	63.918	Seriola_dumerili
FBgn0039016	Dcr-1	67	63.918	ENSSLDG00000012087	dicer1	78	63.918	Seriola_lalandi_dorsalis
FBgn0039016	Dcr-1	74	62.887	ENSSPUG00000016222	DICER1	81	62.887	Sphenodon_punctatus
FBgn0039016	Dcr-1	66	63.918	ENSSPAG00000017128	dicer1	77	63.918	Stegastes_partitus
FBgn0039016	Dcr-1	71	63.918	ENSSSCG00000028225	DICER1	82	63.918	Sus_scrofa
FBgn0039016	Dcr-1	71	54.787	ENSTGUG00000012658	DICER1	80	54.521	Taeniopygia_guttata
FBgn0039016	Dcr-1	67	63.000	ENSTRUG00000006156	dicer1	79	63.000	Takifugu_rubripes
FBgn0039016	Dcr-1	67	63.918	ENSTNIG00000005441	dicer1	78	63.918	Tetraodon_nigroviridis
FBgn0039016	Dcr-1	63	63.918	ENSTTRG00000013044	DICER1	75	46.394	Tursiops_truncatus
FBgn0039016	Dcr-1	66	63.918	ENSUAMG00000011912	DICER1	82	63.918	Ursus_americanus
FBgn0039016	Dcr-1	68	63.918	ENSUMAG00000003027	DICER1	82	63.918	Ursus_maritimus
FBgn0039016	Dcr-1	62	61.957	ENSVPAG00000006817	DICER1	72	61.957	Vicugna_pacos
FBgn0039016	Dcr-1	71	63.918	ENSVVUG00000018855	DICER1	81	63.918	Vulpes_vulpes
FBgn0039016	Dcr-1	70	62.887	ENSXETG00000023315	dicer1	81	62.887	Xenopus_tropicalis
FBgn0039016	Dcr-1	65	65.138	ENSXCOG00000009353	dicer1	80	64.679	Xiphophorus_couchianus
FBgn0039016	Dcr-1	69	58.407	ENSXMAG00000015721	dicer1	80	58.407	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003725	double-stranded RNA binding	10908586.	ISS	Function
GO:0003727	single-stranded RNA binding	21926993.	IDA	Function
GO:0004525	ribonuclease III activity	21873635.	IBA	Function
GO:0004530	deoxyribonuclease I activity	21873635.	IBA	Function
GO:0005515	protein binding	11498593.12368261.15231716.16949822.17666393.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	16530043.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	15918769.16530043.	IDA	Component
GO:0006309	apoptotic DNA fragmentation	21873635.	IBA	Process
GO:0007279	pole cell formation	16949822.	IMP	Process
GO:0007294	germarium-derived oocyte fate determination	22445511.	IMP	Process
GO:0007367	segment polarity determination	16934003.	IGI	Process
GO:0016246	RNA interference	15066284.	IDA	Process
GO:0016246	RNA interference	15066283.	IMP	Process
GO:0016246	RNA interference	12493247.	TAS	Process
GO:0016442	RISC complex	21873635.	IBA	Component
GO:0016442	RISC complex	15066284.	IDA	Component
GO:0016443	bidentate ribonuclease III activity	11201747.	IDA	Function
GO:0030422	production of siRNA involved in RNA interference	21873635.	IBA	Process
GO:0030422	production of siRNA involved in RNA interference	11201747.12368261.	IDA	Process
GO:0030727	germarium-derived female germ-line cyst formation	22445511.	IMP	Process
GO:0031054	pre-miRNA processing	21873635.	IBA	Process
GO:0031054	pre-miRNA processing	17666393.21926993.	IDA	Process
GO:0031054	pre-miRNA processing	15918769.15918770.15985611.	IMP	Process
GO:0031054	pre-miRNA processing	15211354.	TAS	Process
GO:0033227	dsRNA transport	16862146.	IMP	Process
GO:0035068	micro-ribonucleoprotein complex	-	ISS	Component
GO:0035087	siRNA loading onto RISC involved in RNA interference	15066283.	IMP	Process
GO:0035196	production of miRNAs involved in gene silencing by miRNA	15066283.	IMP	Process
GO:0042078	germ-line stem cell division	15944714.	IMP	Process
GO:0042594	response to starvation	25017064.	IMP	Process
GO:0045448	mitotic cell cycle, embryonic	16949822.	IMP	Process
GO:0048813	dendrite morphogenesis	19013069.	IMP	Process
GO:0070578	RISC-loading complex	-	ISS	Component
GO:0070883	pre-miRNA binding	21926993.	IDA	Function