EuRBPDB

Description

RBDs

RBPome

Transcripts

Gene Model

PPI

Paralogs

Gene Ontology

Description

Ensembl ID: FBgn0087035 (Gene tree)
Gene ID: 39683
Gene Symbol: AGO2
Alias: -
Full Name: Argonaute 2
Gene Type: protein_coding
Species: Drosophila_melanogaster
Status: confidence
Strand: Plus strand
Length: 6930 bases
Position: chr3L:15554113-15561042
Accession: FBgn0087035
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
FBpp0304266	PAZ	PF02170.22	1.5e-13	1	1
FBpp0075312	PAZ	PF02170.22	2.9e-13	1	1
FBpp0075313	PAZ	PF02170.22	2.9e-13	1	1
FBpp0304266	Piwi	PF02171.17	2.1e-77	1	1
FBpp0075312	Piwi	PF02171.17	4.9e-77	1	1
FBpp0075313	Piwi	PF02171.17	5e-77	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
27378189	Global changes of the RNA bound proteome during the maternal-to-zygotic transition in Drosophila	IC & embryos.MZT	2016 Jul 5	Sysoev VO	DOI: 10.1038/ncomms12128
27197210	The mRNA-bound proteome of the early fly embryo	IC & embryos	2016 Apr 28	Wessels HH	DOI: 10.1101/gr.200386.115

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
FBtr0331933	-	3784	-	FBpp0304266	787 (aa)	-	A0A1B1LJD3
FBtr0075559	-	4050	-	FBpp0075312	1214 (aa)	-	Q9VUQ5
FBtr0075560	-	4117	-	FBpp0075313	1217 (aa)	-	A0A1B1LJY6

Gene Model

Click here to download FBgn0087035's gene model file

Protein-Protein Interaction (PPI)

Clik here to download FBgn0087035's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
FBgn0087035	AGO2	95	32.873	FBgn0262739	AGO1	84	32.360

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0004521	endoribonuclease activity	16271385.	IDA	Function
GO:0005515	protein binding	11498593.12368261.14508492.16934003.	IPI	Function
GO:0005634	nucleus	26257286.28087276.	IDA	Component
GO:0005737	cytoplasm	19252745.26257286.28087276.	IDA	Component
GO:0005829	cytosol	25294944.	HDA	Component
GO:0007279	pole cell formation	16024657.	IMP	Process
GO:0007349	cellularization	16024657.	IMP	Process
GO:0007367	segment polarity determination	16934003.	IGI	Process
GO:0009047	dosage compensation by hyperactivation of X chromosome	22554892.	IGI	Process
GO:0010526	negative regulation of transposition, RNA-mediated	19516905.	IMP	Process
GO:0016246	RNA interference	16271385.16271386.	IDA	Process
GO:0016246	RNA interference	12368261.16177138.16882716.16934003.28087276.	IMP	Process
GO:0016246	RNA interference	12493247.	TAS	Process
GO:0016442	RISC complex	11498593.14508492.17123955.19661431.	IDA	Component
GO:0016442	RISC complex	12368260.12368261.14559182.	TAS	Component
GO:0030422	production of siRNA involved in RNA interference	11498593.	IDA	Process
GO:0030422	production of siRNA involved in RNA interference	18463630.	IMP	Process
GO:0030423	targeting of mRNA for destruction involved in RNA interference	12011447.	TAS	Process
GO:0033227	dsRNA transport	16862146.	IMP	Process
GO:0035068	micro-ribonucleoprotein complex	-	ISS	Component
GO:0035087	siRNA loading onto RISC involved in RNA interference	17123955.	IDA	Process
GO:0035087	siRNA loading onto RISC involved in RNA interference	15231716.	IMP	Process
GO:0035190	syncytial nuclear migration	16024657.	IMP	Process
GO:0035195	gene silencing by miRNA	25793377.	IMP	Process
GO:0035195	gene silencing by miRNA	16177138.	IMP	Process
GO:0035197	siRNA binding	14615801.16271385.18463636.	IDA	Function
GO:0045071	negative regulation of viral genome replication	19632183.	IMP	Process
GO:0051607	defense response to virus	16556799.20978209.21957285.25770426.	IMP	Process
GO:0070578	RISC-loading complex	17123955.	IDA	Component
GO:0070578	RISC-loading complex	29775584.	IGI	Component
GO:0070868	heterochromatin organization involved in chromatin silencing	19948966.	IMP	Process
GO:0071598	neuronal ribonucleoprotein granule	17178403.	IDA	Component
GO:0098586	cellular response to virus	25770426.	IMP	Process
GO:1990124	messenger ribonucleoprotein complex	17178403.	IDA	Component