Protein disulfide isomerase%3B multifunctional oxidoreductase of the ER lumen%2C essential for disulfide bond formation in secretory and cell-surface proteins%2C processing of non-native disulfide bonds%3B Ero1p activator%3B complexes with exomannosidase%2C Mnl1p to facilitate the recognition of misfolded glycoproteins and the trimming of glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates%2C thereby accelerating ERAD%3B PDI1 has a paralog%2C EUG1%2C that arose from the whole genome duplication
