Guanine nucleotide exchange factor for Gpa1p%3B amplifies G protein signaling%3B functions as a chaperone under ATP-depleted oxidative stress conditions%3B subunit of GET complex%2C involved in ATP dependent Golgi to ER trafficking and insertion of tail-anchored (TA) proteins into ER membrane under non-stress conditions%3B binds as dimer to transmembrane domain (TMD) cargo%2C shielding TMDs from aqueous solvent%3B protein abundance increases under DNA replication stress
