Ubiquitin-conjugating enzyme%3B key E2 partner with Ubc4p for the anaphase-promoting complex (APC)%3B mediates selective degradation of short-lived and abnormal proteins%3B plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD)%3B component of the cellular stress response%3B protein abundance increases in response to DNA replication stress key E2 partner with Ubc4p for the anaphase-promoting complex (APC)