Gamma-glutamyl cyclotransferase%3B cleaves the gamma-glutamyl bond of glutathione to yield 5-oxoproline and a Cys-Gly dipeptide%3B similar to mammalian pro-apoptotic protein ChaC1%3B expression of mouse ChaC1 in yeast increases apoptosis%3B green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus%3B periodically expressed during the metabolic cycle