Essential protein with two zinc fingers%3B present in nucleus of growing cells%2C relocates to cytoplasm in starved cells via a process mediated by Cpr1p%3B binds translation elongation factor eEF-1 (Tef1p)%3B relative distribution to nucleus increases upon DNA replication stress%3B human ZPR1 gene can complement yeast by allowing growth during down-regulation of yeast zpr1