Histone methyltransferase%2C subunit of the COMPASS (Set1C) complex%3B COMPASS methylates histone H3K4%3B Set1p-dependent H3K4 trimethylation recruits Nrd1p%2C allowing efficient termination of snoRNAs and cryptic unstable transcripts (CUTs) by Nrd1p-Nab3p-Sen1p pathway%3B modulates histone acetylation levels in promoter proximal regions to ensure efficient Nrd1p-dependent termination%3B required in transcriptional silencing near telomeres and at silent mating type loci%3B has a SET domain