EuRBPDB

Description

RBDs

RBPome

Transcripts

Gene Model

PPI

Orthologs

Description

Ensembl ID: YHR165C (Gene tree)
Gene ID: -
Gene Symbol: PRP8
Alias: DBF3|DNA39|RNA8|SLT21|USA2
Full Name: -
Gene Type: protein_coding
Species: Saccharomyces_cerevisiae
Status: confidence
Strand: Minus strand
Length: 7242
Position: chrVIII:429707-436948
Accession: S000001208
RBP type: canonical RBP
Summary: Component of U4/U6-U5 snRNP complex%3B involved in second catalytic step of splicing%3B participates in spliceosomal assembly through its interaction with U1 snRNA%3B largest and most evolutionarily conserved protein of the spliceosome%3B mutations in human ortholog%2C PRPF8%2C cause Retinitis pigmentosa and missplicing in Myelodysplastic syndrome%3B mouse ortholog interacts with androgen receptor and may have a role in prostate cancer

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
YHR165C_mRNA	RRM_4	PF10598.9	4.3e-48	1	1
YHR165C_mRNA	U5_2-snRNA_bdg	PF10597.9	8.7e-71	1	1
YHR165C_mRNA	PRO8NT	PF08082.11	4.1e-80	1	1
YHR165C_mRNA	U6-snRNA_bdg	PF10596.9	2.9e-85	1	1
YHR165C_mRNA	PROCN	PF08083.11	6e-219	1	1
YHR165C_mRNA	PRP8_domainIV	PF12134.8	3.5e-122	1	1
YHR165C_mRNA	PROCT	PF08084.11	1e-46	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
26632259	The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs	RIC.PAR_CL & yeast	2015 Dec 3	Beckmann BM	DOI: 10.1038/ncomms10127
26595419	Conserved mRNA-binding proteomes in eukaryotic organisms	mRBPome & yeast	2015 Nov 23	Matia Gonzalez AM	DOI: 10.1038/nsmb.3128
23222640	Global analysis of yeast mRNPs	IC & yeast	2012 Dec 9	Mitchell SF	DOI: 10.1038/nsmb.2468

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
YHR165C_mRNA	-	7242	-	YHR165C_mRNA	2413 (aa)	-	P33334

Gene Model

Click here to download YHR165C's gene model file

Protein-Protein Interaction (PPI)

Clik here to download YHR165C's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
YHR165C	PRP8	95	62.516	ENSG00000174231	PRPF8	99	79.612	Homo_sapiens
YHR165C	PRP8	95	62.559	ENSAPOG00000010079	prpf8	99	62.473	Acanthochromis_polyacanthus
YHR165C	PRP8	95	62.516	ENSAMEG00000007940	PRPF8	99	62.473	Ailuropoda_melanoleuca
YHR165C	PRP8	95	61.116	ENSACIG00000018280	prpf8	98	61.073	Amphilophus_citrinellus
YHR165C	PRP8	95	62.559	ENSAOCG00000010725	prpf8	99	62.473	Amphiprion_ocellaris
YHR165C	PRP8	95	62.559	ENSAPEG00000014397	prpf8	99	62.473	Amphiprion_percula
YHR165C	PRP8	95	62.301	ENSATEG00000010062	prpf8	99	62.215	Anabas_testudineus
YHR165C	PRP8	93	63.063	ENSAPLG00000010357	PRPF8	100	63.019	Anas_platyrhynchos
YHR165C	PRP8	78	64.856	ENSACAG00000014784	PRPF8	98	64.804	Anolis_carolinensis
YHR165C	PRP8	95	62.516	ENSANAG00000032629	PRPF8	99	62.473	Aotus_nancymaae
YHR165C	PRP8	95	62.559	ENSACLG00000020858	prpf8	99	62.516	Astatotilapia_calliptera
YHR165C	PRP8	95	62.602	ENSAMXG00000020291	prpf8	99	62.516	Astyanax_mexicanus
YHR165C	PRP8	95	62.516	ENSBTAG00000011488	PRPF8	99	62.473	Bos_taurus
YHR165C	PRP8	96	60.978	WBGene00004187	prp-8	99	60.892	Caenorhabditis_elegans
YHR165C	PRP8	95	62.516	ENSCJAG00000001911	PRPF8	99	62.473	Callithrix_jacchus
YHR165C	PRP8	95	62.516	ENSCAFG00000019221	PRPF8	99	62.473	Canis_familiaris
YHR165C	PRP8	93	62.992	ENSCAFG00020009943	PRPF8	100	62.948	Canis_lupus_dingo
YHR165C	PRP8	95	62.516	ENSCHIG00000017499	PRPF8	99	62.473	Capra_hircus
YHR165C	PRP8	95	62.516	ENSTSYG00000014120	PRPF8	99	62.473	Carlito_syrichta
YHR165C	PRP8	93	61.953	ENSCAPG00000009459	PRPF8	99	61.909	Cavia_aperea
YHR165C	PRP8	95	62.516	ENSCPOG00000010379	PRPF8	99	62.473	Cavia_porcellus
YHR165C	PRP8	95	62.516	ENSCCAG00000031983	-	99	62.473	Cebus_capucinus
YHR165C	PRP8	95	62.516	ENSCATG00000038595	PRPF8	99	62.473	Cercocebus_atys
YHR165C	PRP8	95	62.516	ENSCLAG00000004388	PRPF8	99	62.473	Chinchilla_lanigera
YHR165C	PRP8	95	62.516	ENSCSAG00000013929	PRPF8	99	62.473	Chlorocebus_sabaeus
YHR165C	PRP8	76	65.859	ENSCHOG00000008590	PRPF8	86	65.859	Choloepus_hoffmanni
YHR165C	PRP8	95	62.516	ENSCPBG00000020409	PRPF8	99	62.473	Chrysemys_picta_bellii
YHR165C	PRP8	96	60.457	ENSCSAVG00000007825	-	100	60.757	Ciona_savignyi
YHR165C	PRP8	95	62.516	ENSCANG00000043088	PRPF8	99	62.473	Colobus_angolensis_palliatus
YHR165C	PRP8	73	62.992	ENSCGRG00000005129	Prpf8	100	62.863	Cricetulus_griseus_crigri
YHR165C	PRP8	95	62.559	ENSCSEG00000007905	prpf8	98	62.473	Cynoglossus_semilaevis
YHR165C	PRP8	95	62.688	ENSDARG00000026180	prpf8	98	62.602	Danio_rerio
YHR165C	PRP8	89	64.176	ENSDNOG00000018471	PRPF8	98	64.130	Dasypus_novemcinctus
YHR165C	PRP8	77	64.815	ENSDORG00000006185	Prpf8	94	64.815	Dipodomys_ordii
YHR165C	PRP8	95	62.441	FBgn0033688	Prp8	96	62.397	Drosophila_melanogaster
YHR165C	PRP8	93	62.882	ENSETEG00000017592	PRPF8	96	62.882	Echinops_telfairi
YHR165C	PRP8	95	60.787	ENSEBUG00000006548	prpf8	98	60.744	Eptatretus_burgeri
YHR165C	PRP8	95	62.516	ENSEASG00005009514	PRPF8	97	64.645	Equus_asinus_asinus
YHR165C	PRP8	94	62.931	ENSECAG00000021318	PRPF8	100	62.887	Equus_caballus
YHR165C	PRP8	61	66.400	ENSEEUG00000012120	-	63	67.669	Erinaceus_europaeus
YHR165C	PRP8	94	62.363	ENSELUG00000007120	prpf8	98	62.275	Esox_lucius
YHR165C	PRP8	95	62.516	ENSFCAG00000006297	PRPF8	99	62.473	Felis_catus
YHR165C	PRP8	95	62.602	ENSFALG00000006628	PRPF8	99	62.559	Ficedula_albicollis
YHR165C	PRP8	95	62.516	ENSFDAG00000004711	PRPF8	99	62.473	Fukomys_damarensis
YHR165C	PRP8	95	62.688	ENSFHEG00000021084	prpf8	98	62.602	Fundulus_heteroclitus
YHR165C	PRP8	96	61.332	ENSGMOG00000002028	prpf8	99	61.246	Gadus_morhua
YHR165C	PRP8	95	62.602	ENSGALG00000002943	PRPF8	99	62.559	Gallus_gallus
YHR165C	PRP8	95	62.473	ENSGAFG00000010337	prpf8	98	62.430	Gambusia_affinis
YHR165C	PRP8	95	62.602	ENSGACG00000008504	prpf8	99	62.516	Gasterosteus_aculeatus
YHR165C	PRP8	95	62.516	ENSGAGG00000008350	PRPF8	99	62.473	Gopherus_agassizii
YHR165C	PRP8	95	62.516	ENSGGOG00000005516	PRPF8	99	62.473	Gorilla_gorilla
YHR165C	PRP8	95	62.516	ENSHBUG00000016192	prpf8	99	62.473	Haplochromis_burtoni
YHR165C	PRP8	95	62.516	ENSHGLG00000012029	PRPF8	99	62.473	Heterocephalus_glaber_female
YHR165C	PRP8	95	62.516	ENSHGLG00100016494	PRPF8	99	62.473	Heterocephalus_glaber_male
YHR165C	PRP8	95	62.559	ENSHCOG00000016414	prpf8	98	62.516	Hippocampus_comes
YHR165C	PRP8	95	62.602	ENSIPUG00000023230	prpf8	99	62.516	Ictalurus_punctatus
YHR165C	PRP8	95	62.516	ENSSTOG00000005128	PRPF8	99	62.473	Ictidomys_tridecemlineatus
YHR165C	PRP8	95	61.283	ENSJJAG00000021159	Prpf8	99	61.240	Jaculus_jaculus
YHR165C	PRP8	95	62.732	ENSKMAG00000016118	prpf8	98	62.645	Kryptolebias_marmoratus
YHR165C	PRP8	95	62.344	ENSLBEG00000026903	prpf8	99	62.258	Labrus_bergylta
YHR165C	PRP8	90	62.312	ENSLACG00000010479	PRPF8	99	64.093	Latimeria_chalumnae
YHR165C	PRP8	95	62.532	ENSLOCG00000005409	prpf8	98	62.532	Lepisosteus_oculatus
YHR165C	PRP8	95	62.516	ENSLAFG00000015445	PRPF8	99	62.473	Loxodonta_africana
YHR165C	PRP8	95	62.516	ENSMFAG00000039995	PRPF8	99	62.473	Macaca_fascicularis
YHR165C	PRP8	95	62.516	ENSMMUG00000004820	PRPF8	99	62.473	Macaca_mulatta
YHR165C	PRP8	95	62.516	ENSMNEG00000035713	PRPF8	99	62.473	Macaca_nemestrina
YHR165C	PRP8	95	62.516	ENSMLEG00000037937	PRPF8	99	62.473	Mandrillus_leucophaeus
YHR165C	PRP8	95	62.559	ENSMAMG00000008919	prpf8	99	62.473	Mastacembelus_armatus
YHR165C	PRP8	95	62.473	ENSMZEG00005015073	prpf8	98	62.430	Maylandia_zebra
YHR165C	PRP8	95	62.602	ENSMGAG00000004769	PRPF8	99	62.559	Meleagris_gallopavo
YHR165C	PRP8	95	62.484	ENSMICG00000010320	PRPF8	99	62.430	Microcebus_murinus
YHR165C	PRP8	95	62.484	ENSMOCG00000016838	Prpf8	99	62.430	Microtus_ochrogaster
YHR165C	PRP8	95	62.215	ENSMMOG00000011887	prpf8	98	62.128	Mola_mola
YHR165C	PRP8	95	62.516	ENSMODG00000010480	PRPF8	99	62.473	Monodelphis_domestica
YHR165C	PRP8	93	62.612	ENSMALG00000003558	prpf8	99	62.612	Monopterus_albus
YHR165C	PRP8	95	62.484	MGP_CAROLIEiJ_G0016740	Prpf8	99	62.430	Mus_caroli
YHR165C	PRP8	95	62.484	ENSMUSG00000020850	Prpf8	99	62.430	Mus_musculus
YHR165C	PRP8	95	62.473	MGP_PahariEiJ_G0017877	Prpf8	99	62.430	Mus_pahari
YHR165C	PRP8	95	62.484	MGP_SPRETEiJ_G0017583	Prpf8	99	62.430	Mus_spretus
YHR165C	PRP8	95	62.516	ENSMPUG00000013227	PRPF8	99	62.473	Mustela_putorius_furo
YHR165C	PRP8	95	62.349	ENSMLUG00000002666	PRPF8	99	62.349	Myotis_lucifugus
YHR165C	PRP8	95	60.879	ENSNGAG00000005305	Prpf8	99	60.879	Nannospalax_galili
YHR165C	PRP8	95	62.516	ENSNBRG00000013127	prpf8	98	62.473	Neolamprologus_brichardi
YHR165C	PRP8	92	62.972	ENSNLEG00000000897	PRPF8	97	62.972	Nomascus_leucogenys
YHR165C	PRP8	95	61.342	ENSMEUG00000015999	PRPF8	99	61.299	Notamacropus_eugenii
YHR165C	PRP8	95	61.917	ENSOPRG00000003102	PRPF8	99	61.864	Ochotona_princeps
YHR165C	PRP8	95	62.516	ENSODEG00000008468	PRPF8	99	62.473	Octodon_degus
YHR165C	PRP8	95	62.516	ENSONIG00000008153	prpf8	98	62.473	Oreochromis_niloticus
YHR165C	PRP8	79	63.989	ENSOANG00000004250	PRPF8	98	63.989	Ornithorhynchus_anatinus
YHR165C	PRP8	95	62.516	ENSOCUG00000000081	PRPF8	99	62.473	Oryctolagus_cuniculus
YHR165C	PRP8	96	62.377	ENSORLG00000008036	prpf8	99	62.307	Oryzias_latipes
YHR165C	PRP8	96	62.350	ENSORLG00020021070	prpf8	98	62.307	Oryzias_latipes_hni
YHR165C	PRP8	96	62.377	ENSORLG00015002340	prpf8	98	62.334	Oryzias_latipes_hsok
YHR165C	PRP8	95	61.568	ENSOMEG00000016866	prpf8	98	61.601	Oryzias_melastigma
YHR165C	PRP8	95	62.435	ENSOARG00000013312	PRPF8	99	62.392	Ovis_aries
YHR165C	PRP8	95	62.516	ENSPPAG00000042753	PRPF8	99	62.473	Pan_paniscus
YHR165C	PRP8	95	62.516	ENSPPRG00000008746	PRPF8	99	62.473	Panthera_pardus
YHR165C	PRP8	95	62.473	ENSPTIG00000019200	PRPF8	99	62.430	Panthera_tigris_altaica
YHR165C	PRP8	95	62.516	ENSPTRG00000039576	PRPF8	99	62.473	Pan_troglodytes
YHR165C	PRP8	96	62.505	ENSPANG00000024607	PRPF8	99	62.462	Papio_anubis
YHR165C	PRP8	95	62.559	ENSPKIG00000011201	prpf8	98	62.473	Paramormyrops_kingsleyae
YHR165C	PRP8	95	62.473	ENSPSIG00000013393	PRPF8	99	62.430	Pelodiscus_sinensis
YHR165C	PRP8	95	62.484	ENSPEMG00000021699	Prpf8	99	62.430	Peromyscus_maniculatus_bairdii
YHR165C	PRP8	93	61.460	ENSPMAG00000005438	prpf8	100	61.460	Petromyzon_marinus
YHR165C	PRP8	95	62.516	ENSPCIG00000022603	PRPF8	100	62.948	Phascolarctos_cinereus
YHR165C	PRP8	95	62.559	ENSPFOG00000007005	prpf8	98	62.516	Poecilia_formosa
YHR165C	PRP8	95	61.525	ENSPLAG00000020777	prpf8	99	61.482	Poecilia_latipinna
YHR165C	PRP8	95	62.559	ENSPMEG00000004051	prpf8	98	62.516	Poecilia_mexicana
YHR165C	PRP8	95	62.559	ENSPREG00000021902	prpf8	99	62.516	Poecilia_reticulata
YHR165C	PRP8	95	62.516	ENSPPYG00000007777	PRPF8	99	62.473	Pongo_abelii
YHR165C	PRP8	86	66.234	ENSPCAG00000008938	PRPF8	89	66.234	Procavia_capensis
YHR165C	PRP8	95	62.484	ENSPCOG00000015182	PRPF8	99	62.430	Propithecus_coquereli
YHR165C	PRP8	88	65.886	ENSPVAG00000002134	PRPF8	90	65.831	Pteropus_vampyrus
YHR165C	PRP8	95	62.516	ENSPNYG00000016356	prpf8	99	62.473	Pundamilia_nyererei
YHR165C	PRP8	97	61.871	ENSPNAG00000009247	prpf8	99	62.559	Pygocentrus_nattereri
YHR165C	PRP8	95	62.484	ENSRNOG00000003495	Prpf8	99	62.430	Rattus_norvegicus
YHR165C	PRP8	95	62.516	ENSRBIG00000031219	PRPF8	100	62.815	Rhinopithecus_bieti
YHR165C	PRP8	95	62.516	ENSRROG00000038014	PRPF8	100	62.815	Rhinopithecus_roxellana
YHR165C	PRP8	95	62.516	ENSSBOG00000029717	PRPF8	99	62.473	Saimiri_boliviensis_boliviensis
YHR165C	PRP8	95	62.516	ENSSHAG00000006167	PRPF8	99	62.473	Sarcophilus_harrisii
YHR165C	PRP8	95	62.645	ENSSFOG00015013905	prpf8	98	62.559	Scleropages_formosus
YHR165C	PRP8	95	62.516	ENSSMAG00000017736	prpf8	99	62.430	Scophthalmus_maximus
YHR165C	PRP8	95	62.559	ENSSDUG00000003029	prpf8	99	62.473	Seriola_dumerili
YHR165C	PRP8	66	63.873	ENSSLDG00000017096	prpf8	100	63.873	Seriola_lalandi_dorsalis
YHR165C	PRP8	80	67.406	ENSSARG00000002892	PRPF8	83	67.406	Sorex_araneus
YHR165C	PRP8	95	62.387	ENSSPUG00000007463	PRPF8	99	62.344	Sphenodon_punctatus
YHR165C	PRP8	95	61.999	ENSSPAG00000015639	prpf8	98	61.913	Stegastes_partitus
YHR165C	PRP8	95	62.516	ENSSSCG00000017817	PRPF8	99	62.473	Sus_scrofa
YHR165C	PRP8	50	67.190	ENSTGUG00000015597	-	95	67.190	Taeniopygia_guttata
YHR165C	PRP8	95	62.602	ENSTGUG00000005648	-	99	62.559	Taeniopygia_guttata
YHR165C	PRP8	95	62.344	ENSTRUG00000015906	prpf8	99	62.258	Takifugu_rubripes
YHR165C	PRP8	91	63.960	ENSTNIG00000003460	prpf8	98	63.960	Tetraodon_nigroviridis
YHR165C	PRP8	85	68.216	ENSTBEG00000006431	PRPF8	88	68.148	Tupaia_belangeri
YHR165C	PRP8	95	62.085	ENSTTRG00000006869	PRPF8	99	62.042	Tursiops_truncatus
YHR165C	PRP8	51	61.452	ENSUAMG00000015644	-	94	61.371	Ursus_americanus
YHR165C	PRP8	95	62.301	ENSUMAG00000009385	PRPF8	99	62.258	Ursus_maritimus
YHR165C	PRP8	64	75.694	ENSVPAG00000006063	-	66	75.694	Vicugna_pacos
YHR165C	PRP8	95	62.516	ENSVVUG00000021695	PRPF8	98	62.473	Vulpes_vulpes
YHR165C	PRP8	95	62.543	ENSXETG00000022259	prpf8	99	62.446	Xenopus_tropicalis
YHR165C	PRP8	95	62.516	ENSXCOG00000012775	prpf8	98	62.473	Xiphophorus_couchianus
YHR165C	PRP8	95	62.516	ENSXMAG00000008505	prpf8	98	62.473	Xiphophorus_maculatus