Histone methyltransferase with a role in transcriptional elongation%3B methylates H3 lysine 36 (H3K36)%2C which suppresses incorporation of acetylated histones and signals for the deacetylation of these histones within transcribed genes%3B associates with the C-terminal domain(CTD) of Rpo21p%3B H3K36me3 (trimethylation) requires Spt6p%2C proline 38 on H3%2C CTD of Rpo21p%2C Ctk1p%2C and C-terminal SRI domain of Ste2p%3B relocalizes to the cytosol in response to hypoxia
