EuRBPDB

Description

RBDs

RBPome

Transcripts

Gene Model

PPI

Orthologs

Description

Ensembl ID: YKL149C (Gene tree)
Gene ID: -
Gene Symbol: DBR1
Alias: PRP26
Full Name: -
Gene Type: protein_coding
Species: Saccharomyces_cerevisiae
Status: confidence
Strand: Minus strand
Length: 1218
Position: chrXI:167612-168829
Accession: S000001632
RBP type: canonical RBP
Summary: RNA lariat debranching enzyme%3B catalyzes debranching of lariat introns formed during pre-mRNA splicing%3B required for efficient Ty1 transposition%3B knockdown of human homolog Dbr1 rescues toxicity of RNA-binding proteins TDP-43 and FUS which are implicated in amyotrophic lateral sclerosis (ALS)%2C suggests potential therapeutic target for ALS and related TDP-43 proteinopathies%3B human homolog DBR1 can complement yeast dbr1 null mutant

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
YKL149C_mRNA	DBR1	PF05011.13	1.3e-12	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
26632259	The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs	RIC.PAR_CL & yeast	2015 Dec 3	Beckmann BM	DOI: 10.1038/ncomms10127

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
YKL149C_mRNA	-	1218	-	YKL149C_mRNA	405 (aa)	-	P24309

Gene Model

Click here to download YKL149C's gene model file

Protein-Protein Interaction (PPI)

Clik here to download YKL149C's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
YKL149C	DBR1	79	40.308	ENSG00000138231	DBR1	92	48.148	Homo_sapiens
YKL149C	DBR1	87	36.975	ENSAPOG00000004318	dbr1	55	36.975	Acanthochromis_polyacanthus
YKL149C	DBR1	78	40.062	ENSAMEG00000006272	DBR1	51	40.062	Ailuropoda_melanoleuca
YKL149C	DBR1	87	37.921	ENSACIG00000020512	dbr1	54	37.640	Amphilophus_citrinellus
YKL149C	DBR1	87	36.415	ENSAOCG00000008060	dbr1	55	36.415	Amphiprion_ocellaris
YKL149C	DBR1	87	36.415	ENSAPEG00000021944	dbr1	55	36.415	Amphiprion_percula
YKL149C	DBR1	87	37.640	ENSATEG00000019673	dbr1	56	37.360	Anabas_testudineus
YKL149C	DBR1	89	38.630	ENSACAG00000016760	DBR1	57	38.630	Anolis_carolinensis
YKL149C	DBR1	78	40.187	ENSANAG00000028952	DBR1	50	40.187	Aotus_nancymaae
YKL149C	DBR1	87	39.326	ENSACLG00000024027	dbr1	57	39.045	Astatotilapia_calliptera
YKL149C	DBR1	87	38.202	ENSAMXG00000030736	dbr1	52	38.202	Astyanax_mexicanus
YKL149C	DBR1	79	39.385	ENSBTAG00000019949	DBR1	51	39.385	Bos_taurus
YKL149C	DBR1	86	35.537	WBGene00000937	dbr-1	61	35.537	Caenorhabditis_elegans
YKL149C	DBR1	78	40.187	ENSCJAG00000002433	DBR1	50	40.187	Callithrix_jacchus
YKL149C	DBR1	78	40.752	ENSCAFG00000007501	DBR1	50	40.752	Canis_familiaris
YKL149C	DBR1	78	40.752	ENSCAFG00020008060	DBR1	50	40.752	Canis_lupus_dingo
YKL149C	DBR1	78	39.875	ENSCHIG00000026937	DBR1	50	39.875	Capra_hircus
YKL149C	DBR1	78	41.433	ENSTSYG00000005317	DBR1	51	40.923	Carlito_syrichta
YKL149C	DBR1	79	37.231	ENSCPOG00000006179	DBR1	50	37.695	Cavia_porcellus
YKL149C	DBR1	78	40.810	ENSCCAG00000025708	DBR1	51	40.810	Cebus_capucinus
YKL149C	DBR1	79	40.308	ENSCATG00000032054	DBR1	51	40.308	Cercocebus_atys
YKL149C	DBR1	79	40.308	ENSCLAG00000001800	DBR1	51	40.308	Chinchilla_lanigera
YKL149C	DBR1	79	40.615	ENSCSAG00000010977	DBR1	51	40.615	Chlorocebus_sabaeus
YKL149C	DBR1	87	38.202	ENSCING00000011388	-	69	38.202	Ciona_intestinalis
YKL149C	DBR1	80	40.303	ENSCSAVG00000007545	-	75	40.303	Ciona_savignyi
YKL149C	DBR1	79	40.000	ENSCANG00000024237	DBR1	51	40.000	Colobus_angolensis_palliatus
YKL149C	DBR1	79	40.000	ENSCGRG00001018497	Dbr1	51	40.000	Cricetulus_griseus_chok1gshd
YKL149C	DBR1	86	37.500	ENSCSEG00000002813	dbr1	52	37.216	Cynoglossus_semilaevis
YKL149C	DBR1	82	38.024	ENSCVAG00000019969	dbr1	51	37.725	Cyprinodon_variegatus
YKL149C	DBR1	85	39.031	ENSDARG00000056923	dbr1	52	38.462	Danio_rerio
YKL149C	DBR1	78	40.187	ENSDNOG00000043630	DBR1	50	40.187	Dasypus_novemcinctus
YKL149C	DBR1	86	38.028	FBgn0035838	ldbr	62	38.592	Drosophila_melanogaster
YKL149C	DBR1	94	36.623	ENSEBUG00000007494	dbr1	60	36.623	Eptatretus_burgeri
YKL149C	DBR1	79	40.000	ENSEASG00005003788	DBR1	51	40.000	Equus_asinus_asinus
YKL149C	DBR1	79	40.000	ENSECAG00000013920	DBR1	51	40.000	Equus_caballus
YKL149C	DBR1	79	32.000	ENSEEUG00000007059	DBR1	51	32.000	Erinaceus_europaeus
YKL149C	DBR1	96	36.896	ENSELUG00000005587	dbr1	59	36.896	Esox_lucius
YKL149C	DBR1	79	40.308	ENSFCAG00000002229	DBR1	51	40.308	Felis_catus
YKL149C	DBR1	79	40.000	ENSFDAG00000009524	DBR1	50	40.498	Fukomys_damarensis
YKL149C	DBR1	82	39.233	ENSFHEG00000001743	dbr1	51	38.938	Fundulus_heteroclitus
YKL149C	DBR1	87	38.244	ENSGMOG00000006925	dbr1	54	38.244	Gadus_morhua
YKL149C	DBR1	83	39.181	ENSGAFG00000001046	dbr1	54	38.889	Gambusia_affinis
YKL149C	DBR1	87	36.544	ENSGACG00000009122	dbr1	54	36.544	Gasterosteus_aculeatus
YKL149C	DBR1	78	38.245	ENSGAGG00000001244	DBR1	51	38.245	Gopherus_agassizii
YKL149C	DBR1	87	39.326	ENSHBUG00000000882	dbr1	54	39.045	Haplochromis_burtoni
YKL149C	DBR1	78	40.187	ENSHGLG00000014529	Dbr1	51	39.875	Heterocephalus_glaber_female
YKL149C	DBR1	78	40.187	ENSHGLG00100013202	Dbr1	51	39.875	Heterocephalus_glaber_male
YKL149C	DBR1	87	37.640	ENSHCOG00000004179	dbr1	55	37.360	Hippocampus_comes
YKL149C	DBR1	83	37.463	ENSIPUG00000023749	dbr1	50	37.463	Ictalurus_punctatus
YKL149C	DBR1	79	40.308	ENSSTOG00000007122	DBR1	51	40.000	Ictidomys_tridecemlineatus
YKL149C	DBR1	78	41.121	ENSJJAG00000017080	Dbr1	50	41.121	Jaculus_jaculus
YKL149C	DBR1	87	38.227	ENSKMAG00000004869	dbr1	56	37.950	Kryptolebias_marmoratus
YKL149C	DBR1	83	38.012	ENSLBEG00000021307	dbr1	50	37.758	Labrus_bergylta
YKL149C	DBR1	78	40.125	ENSLACG00000005547	DBR1	50	40.125	Latimeria_chalumnae
YKL149C	DBR1	87	38.827	ENSLOCG00000004160	dbr1	54	38.827	Lepisosteus_oculatus
YKL149C	DBR1	79	39.692	ENSLAFG00000005827	DBR1	51	39.692	Loxodonta_africana
YKL149C	DBR1	79	40.308	ENSMFAG00000043642	DBR1	51	40.308	Macaca_fascicularis
YKL149C	DBR1	79	40.308	ENSMMUG00000021284	DBR1	51	40.308	Macaca_mulatta
YKL149C	DBR1	79	40.308	ENSMNEG00000041740	DBR1	51	40.308	Macaca_nemestrina
YKL149C	DBR1	87	37.360	ENSMAMG00000012205	dbr1	53	37.079	Mastacembelus_armatus
YKL149C	DBR1	87	39.326	ENSMZEG00005021338	dbr1	54	39.045	Maylandia_zebra
YKL149C	DBR1	79	40.308	ENSMAUG00000010037	Dbr1	51	40.308	Mesocricetus_auratus
YKL149C	DBR1	78	40.439	ENSMICG00000049533	DBR1	50	40.439	Microcebus_murinus
YKL149C	DBR1	79	39.692	ENSMOCG00000018746	Dbr1	52	39.692	Microtus_ochrogaster
YKL149C	DBR1	85	39.093	ENSMMOG00000000719	dbr1	52	39.093	Mola_mola
YKL149C	DBR1	79	39.441	ENSMODG00000018554	DBR1	51	39.441	Monodelphis_domestica
YKL149C	DBR1	87	35.933	ENSMALG00000022283	dbr1	52	35.933	Monopterus_albus
YKL149C	DBR1	79	40.000	MGP_CAROLIEiJ_G0032564	Dbr1	98	33.884	Mus_caroli
YKL149C	DBR1	79	40.000	ENSMUSG00000032469	Dbr1	98	33.884	Mus_musculus
YKL149C	DBR1	79	40.000	MGP_PahariEiJ_G0015433	Dbr1	98	33.884	Mus_pahari
YKL149C	DBR1	79	40.000	MGP_SPRETEiJ_G0033708	Dbr1	98	33.884	Mus_spretus
YKL149C	DBR1	79	40.000	ENSMPUG00000009230	DBR1	51	40.000	Mustela_putorius_furo
YKL149C	DBR1	78	40.810	ENSMLUG00000026117	DBR1	50	40.810	Myotis_lucifugus
YKL149C	DBR1	79	40.000	ENSNGAG00000003518	Dbr1	51	40.000	Nannospalax_galili
YKL149C	DBR1	87	39.326	ENSNBRG00000016318	dbr1	54	39.045	Neolamprologus_brichardi
YKL149C	DBR1	78	40.498	ENSNLEG00000032263	DBR1	50	40.000	Nomascus_leucogenys
YKL149C	DBR1	79	39.130	ENSMEUG00000009188	DBR1	51	39.130	Notamacropus_eugenii
YKL149C	DBR1	78	39.875	ENSODEG00000018178	DBR1	50	39.875	Octodon_degus
YKL149C	DBR1	87	38.764	ENSONIG00000013801	dbr1	53	38.483	Oreochromis_niloticus
YKL149C	DBR1	87	37.921	ENSORLG00015001112	dbr1	57	37.921	Oryzias_latipes_hsok
YKL149C	DBR1	87	37.677	ENSOMEG00000000857	dbr1	57	37.394	Oryzias_melastigma
YKL149C	DBR1	79	40.000	ENSOGAG00000033095	DBR1	51	40.000	Otolemur_garnettii
YKL149C	DBR1	78	38.629	ENSOARG00000007589	DBR1	50	38.629	Ovis_aries
YKL149C	DBR1	79	40.308	ENSPPAG00000031137	DBR1	51	40.308	Pan_paniscus
YKL149C	DBR1	79	40.615	ENSPPRG00000013629	DBR1	51	40.615	Panthera_pardus
YKL149C	DBR1	79	40.615	ENSPTRG00000015441	DBR1	51	40.615	Pan_troglodytes
YKL149C	DBR1	79	40.308	ENSPANG00000012664	DBR1	51	40.308	Papio_anubis
YKL149C	DBR1	87	36.827	ENSPKIG00000000310	dbr1	53	36.827	Paramormyrops_kingsleyae
YKL149C	DBR1	79	40.000	ENSPEMG00000020602	Dbr1	51	40.000	Peromyscus_maniculatus_bairdii
YKL149C	DBR1	78	37.025	ENSPMAG00000008620	dbr1	72	37.025	Petromyzon_marinus
YKL149C	DBR1	78	40.252	ENSPCIG00000006494	DBR1	50	40.252	Phascolarctos_cinereus
YKL149C	DBR1	83	38.596	ENSPLAG00000011665	dbr1	54	38.304	Poecilia_latipinna
YKL149C	DBR1	83	38.889	ENSPMEG00000010080	dbr1	53	38.596	Poecilia_mexicana
YKL149C	DBR1	83	38.889	ENSPREG00000020157	dbr1	54	38.596	Poecilia_reticulata
YKL149C	DBR1	79	40.308	ENSPPYG00000014139	DBR1	51	40.308	Pongo_abelii
YKL149C	DBR1	79	40.000	ENSPCAG00000012956	DBR1	71	40.000	Procavia_capensis
YKL149C	DBR1	78	40.439	ENSPCOG00000016894	DBR1	50	40.439	Propithecus_coquereli
YKL149C	DBR1	78	32.288	ENSPVAG00000007713	DBR1	50	32.288	Pteropus_vampyrus
YKL149C	DBR1	87	39.045	ENSPNYG00000015453	dbr1	53	38.764	Pundamilia_nyererei
YKL149C	DBR1	83	37.427	ENSPNAG00000025595	dbr1	54	36.842	Pygocentrus_nattereri
YKL149C	DBR1	79	40.000	ENSRNOG00000014588	Dbr1	51	40.000	Rattus_norvegicus
YKL149C	DBR1	78	40.752	ENSRBIG00000045002	DBR1	51	40.248	Rhinopithecus_bieti
YKL149C	DBR1	78	40.752	ENSRROG00000044819	DBR1	51	40.248	Rhinopithecus_roxellana
YKL149C	DBR1	78	40.498	ENSSBOG00000032048	DBR1	50	40.498	Saimiri_boliviensis_boliviensis
YKL149C	DBR1	78	40.379	ENSSHAG00000006752	DBR1	50	40.379	Sarcophilus_harrisii
YKL149C	DBR1	83	38.643	ENSSFOG00015011410	dbr1	54	38.643	Scleropages_formosus
YKL149C	DBR1	87	37.640	ENSSMAG00000016078	dbr1	54	37.360	Scophthalmus_maximus
YKL149C	DBR1	87	37.360	ENSSDUG00000017849	dbr1	53	37.360	Seriola_dumerili
YKL149C	DBR1	87	37.079	ENSSLDG00000019891	dbr1	53	37.079	Seriola_lalandi_dorsalis
YKL149C	DBR1	77	39.748	ENSSARG00000009558	-	50	39.748	Sorex_araneus
YKL149C	DBR1	87	36.236	ENSSPAG00000016892	dbr1	54	36.236	Stegastes_partitus
YKL149C	DBR1	79	39.385	ENSSSCG00000031098	DBR1	52	39.385	Sus_scrofa
YKL149C	DBR1	87	36.842	ENSTRUG00000021594	dbr1	55	36.565	Takifugu_rubripes
YKL149C	DBR1	87	36.313	ENSTNIG00000006710	dbr1	54	36.212	Tetraodon_nigroviridis
YKL149C	DBR1	79	40.308	ENSTTRG00000004020	DBR1	51	40.308	Tursiops_truncatus
YKL149C	DBR1	78	40.498	ENSUAMG00000004639	DBR1	50	40.498	Ursus_americanus
YKL149C	DBR1	79	40.000	ENSUMAG00000015012	DBR1	51	40.000	Ursus_maritimus
YKL149C	DBR1	79	36.957	ENSVPAG00000011711	DBR1	51	36.957	Vicugna_pacos
YKL149C	DBR1	78	40.752	ENSVVUG00000026604	DBR1	50	40.752	Vulpes_vulpes
YKL149C	DBR1	78	39.185	ENSXETG00000027491	dbr1	51	39.185	Xenopus_tropicalis
YKL149C	DBR1	83	38.889	ENSXCOG00000018078	dbr1	53	38.596	Xiphophorus_couchianus
YKL149C	DBR1	83	38.889	ENSXMAG00000007311	dbr1	53	38.596	Xiphophorus_maculatus