EuRBPDB

Ensembl ID

YMR190C (Gene tree)

Gene ID

-

Gene Symbol

-

Alias

-

Full Name

-

Gene Type

protein_coding

Species

Saccharomyces_cerevisiae

Status

putative

Strand

Minus strand

Length

4344

Position

chrXIII:640915-645258

Accession

S000004802

RBP type

canonical RBP

Summary

RecQ family nucleolar DNA helicase%3B role in genome integrity maintenance%2C chromosome synapsis%2C meiotic joint molecule/crossover formation%3B stimulates activity of Top3p%3B rapidly lost in response to rapamycin in Rrd1p-dependent manner%3B forms nuclear foci upon DNA replication stress%3B yeast SGS1 complements mutations in human homolog BLM implicated in Bloom syndrome%3B also similar to human WRN implicated in Werner syndrome%3B human BLM and WRN can each complement yeast null mutant