EuRBPDB

Description

Ensembl ID: YOR204W (Gene tree)
Gene ID: -
Gene Symbol: DED1
Alias: SPP81
Full Name: -
Gene Type: protein_coding
Species: Saccharomyces_cerevisiae
Status: confidence
Strand: Plus strand
Length: 1815
Position: chrXV:722911-724725
Accession: S000005730
RBP type: canonical RBP
Summary: ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase%3B required for translation initiation of all yeast mRNAs%3B binds to mRNA cap-associated factors%2C and binding stimulates Ded1p RNA-dependent ATPase activity%3B mutation in human homolog DBY is associated with male infertility%3B human homolog DDX3X complements ded1 null mutation%3B DED1 has a paralog%2C DBP1%2C that arose from the whole genome duplication

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
YOR204W_mRNA	DEAD	PF00270.29	7.9e-51	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
26632259	The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs	RIC.PAR_CL & yeast	2015 Dec 3	Beckmann BM	DOI: 10.1038/ncomms10127
25173706	Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins	RNPxl.PAR_CL & yeast	2014 Aug 31	Kramer K	DOI: 10.1038/nmeth.3092
26595419	Conserved mRNA-binding proteomes in eukaryotic organisms	mRBPome & yeast	2015 Nov 23	Matia Gonzalez AM	DOI: 10.1038/nsmb.3128
23222640	Global analysis of yeast mRNPs	IC & yeast	2012 Dec 9	Mitchell SF	DOI: 10.1038/nsmb.2468
21124907	A screen for RNA binding proteins in yeast indicates dual functions for many enzymes	ProtoArray & yeast	2010 Nov 11	DOI: 10.1371/journal.pone.0015499
20844764	Proteome-wide search reveals unexpected RNA binding proteins in Saccharomyces cerevisiae	MS & yeast	2010 Sep 10	Tsvetanova NG	DOI: 10.1371/journal.pone.0012671

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
					(aa)

Gene Model

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
YOR204W	DED1	68	40.095	YGL078C	-	83	38.938
YOR204W	DED1	64	31.959	YJL138C	TIF2	93	31.959
YOR204W	DED1	58	31.844	YMR290C	-	68	31.844
YOR204W	DED1	59	52.273	YLR276C	-	60	52.273
YOR204W	DED1	61	37.057	YHR065C	-	72	36.483
YOR204W	DED1	69	31.364	YHR169W	-	98	31.674
YOR204W	DED1	69	31.019	YGL171W	-	73	31.019
YOR204W	DED1	65	37.408	YDR243C	-	68	37.408
YOR204W	DED1	60	32.000	YOR046C	DBP5	73	32.000
YOR204W	DED1	59	33.241	YDL084W	-	77	32.687
YOR204W	DED1	64	33.838	YDR021W	-	92	33.924
YOR204W	DED1	100	67.874	YPL119C	DBP1	96	69.652
YOR204W	DED1	64	30.445	YDR194C	-	62	30.445
YOR204W	DED1	61	31.635	YDL160C	-	69	31.436
YOR204W	DED1	66	45.636	YNL112W	-	76	44.626
YOR204W	DED1	64	31.959	YKR059W	TIF1	93	31.959
YOR204W	DED1	64	30.290	YBR142W	-	55	30.290

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
YOR204W	DED1	83	51.772	WBGene00002244	laf-1	72	54.158	Caenorhabditis_elegans
YOR204W	DED1	96	47.384	ENSCING00000007637	-	75	56.687	Ciona_intestinalis
YOR204W	DED1	74	60.352	FBgn0263231	bel	68	57.510	Drosophila_melanogaster
YOR204W	DED1	85	53.686	ENSEBUG00000014402	-	70	58.030	Eptatretus_burgeri
YOR204W	DED1	84	54.426	ENSPMAG00000003524	-	89	57.143	Petromyzon_marinus