EuRBPDB

Mus_musculus_c3hhejFamily: Caprin-1_C Number of Genes: 2

Ensembl ID	Symbol	Entrez ID	RBD	RBPome	PRI	Expresion	Pathway	Phenotype	Paralog	Ortholog	GO
MGP_C3HHeJ_G0025928	Caprin1	-
MGP_C3HHeJ_G0031209	Caprin2	-

Introduction

Pfam

This family of proteins is found in eukaryotes. Proteins in this family are typically between 343 and 708 amino acids in length. This family is the C terminal region of caprin-1. Caprin-1 is a protein involved in regulating cellular proliferation. In mutated phenotypes, the G1 phase of the cell cycle is greatly lengthened, impairing normal proliferation. The C terminal region of caprin-1 contains RGG motifs which are characteristic of RNA binding domains. It is possible that caprin-1 functions through an RNA binding mechanism.

InterPro

This family of proteins is found in eukaryotes. Proteins in this family are typically between 343 and 708 amino acids in length. This family is the C-terminal region of caprin-1. Caprin-1 is a protein involved in regulating cellular proliferation. In mutated phenotypes, the G1 phase of the cell cycle is greatly lengthened, impairing normal proliferation. The C-terminal region of caprin-1 contains RGG motifs which are characteristic of RNA binding domains. It is possible that caprin-1 functions through an RNA binding mechanism.

Reference

Wang B, David MD, Schrader JW;, J Immunol. 2005;175:4274-4282.: Absence of caprin-1 results in defects in cellular proliferation. PUBMED:16177067 EPMC:16177067.