This presumed domain is found at the C-terminus of lariat debranching enzyme. This domain is always found in association with PF00149.
This presumed domain is found at the C terminus of lariat debranching enzyme. This domain is always found in association with a metallo-phosphoesterase domain INTERPRO. RNA lariat debranching enzyme is capable of digesting a variety of branched nucleic acid substrates and multicopy single-stranded DNAs. The enzyme degrades intron lariat structures during splicing.
Nam K, Lee G, Trambley J, Devine SE, Boeke JD; , Mol Cell Biol 1997;17:809-818.: Severe growth defect in a Schizosaccharomyces pombe mutant defective in intron lariat degradation. PUBMED:9001235 EPMC:9001235 .