Caenorhabditis_elegansFamily: Ebp2 Number of Genes: 1
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
C18A3.3
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Introduction

Pfam

This family consists of several Eukaryotic rRNA processing protein EBP2 sequences. Ebp2p is required for the maturation of 25S rRNA and 60S subunit assembly. Ebp2p may be one of the target proteins of Rrs1p for executing the signal to regulate ribosome biogenesis [1]. This family also plays a role in chromosome segregation [2].

InterPro

No InterPro abstract

Reference

  1. Tsujii R, Miyoshi K, Tsuno A, Matsui Y, Toh-e A, Miyakawa T, Mizuta K; , Genes Cells 2000;5:543-553.: Ebp2p, yeast homologue of a human protein that interacts with Epstein-Barr virus nuclear antigen 1, is required for pre-rRNA processing and ribosomal subunit assembly. PUBMED:10947841 EPMC:10947841 .

  2. Ionescu CN, Origanti S, McAlear MA; , Yeast 2004;21:1219-1232.: The yeast rRNA biosynthesis factor Ebp2p is also required for efficient nuclear division. PUBMED:15515129 EPMC:15515129.