Endonuclease V is specific for single-stranded DNA or for duplex DNA that contains uracil or that is damaged by a variety of agents .
Endonuclease V is specific for single-stranded DNA, for duplex DNA that contains uracil, or that is damaged [PUBMED:8990280]. Matrix metalloproteinase-1 (MMP-1) is the major enzyme responsible for collagen 1 digestion. It is induced by exposure to sunlight, but is reduced with treatment of DNA repair enzyme endonuclease V [PUBMED:18459971]. This family consequently has potential medical importance [PUBMED:18328204].