EuRBPDB

Anabas_testudineusFamily: Exo_endo_phos Number of Genes: 31

Ensembl ID	Symbol	Entrez ID
ENSATEG00000001862	angel1	113159912
ENSATEG00000002306	synj1	113168846
ENSATEG00000002743	inpp5e	113151331
ENSATEG00000002883	apex1	113164025
ENSATEG00000003072	pde12	113154316
ENSATEG00000005476	smpd5	113170850
ENSATEG00000006407	inppl1a	113170376
ENSATEG00000006758	-	-
ENSATEG00000007862	cnot6b	113160426
ENSATEG00000008774	cnot6l	113150278
ENSATEG00000009627	INPP5A	113159306
ENSATEG00000009966	inpp5b	113169734
ENSATEG00000010663	-	113163094
ENSATEG00000011290	inpp5jb	-
ENSATEG00000011360	inpp5d	113152421
ENSATEG00000015612	nocta	-
ENSATEG00000015888	dnase1 (1 of many)	113153679
ENSATEG00000015946	dnase1 (1 of many)	113153671
ENSATEG00000016075	inppl1b	113160143
ENSATEG00000017009	inpp5ja	-
ENSATEG00000018445	ocrl	113160283
ENSATEG00000018710	dnase1l1l	113167884
ENSATEG00000020329	inpp5ka	113172233
ENSATEG00000021792	inpp5kb	113170549
ENSATEG00000022147	-	-
ENSATEG00000022975	noctb	113162250
ENSATEG00000022981	-	113167679
ENSATEG00000023149	inpp5l	113151304
ENSATEG00000023174	angel2	113149759
ENSATEG00000023600	apex2	113166935
ENSATEG00000025113	smpd2b	113154357

Introduction

Pfam

This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling [1]. This family includes: AP endonuclease proteins EC:4.2.99.18 e.g P27695 DNase I proteins EC:3.1.21.1 e.g. P24855 Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56 O43426 Sphingomyelinase EC:3.1.4.12 P11889 and Nocturnin O35710.

InterPro

This domain is found in a large number of proteins including magnesium dependent endonucleases and phosphatases involved in intracellular signalling [PUBMED:10838565]. Proteins this domain is found in include: AP endonuclease proteins (EC), DNase I proteins (EC), Synaptojanin an inositol-1,4,5-trisphosphate phosphatase (EC) and Sphingomyelinase (EC).

Reference

Dlakic M; , Trends Biochem Sci 2000;25:272-273.: Functionally unrelated signalling proteins contain a fold similar to Mg2+-dependent endonucleases. PUBMED:10838565 EPMC:10838565 .
Mol CD, Kuo CF, Thayer MM, Cunningham RP, Tainer JA; , Nature 1995;374:381-386.: Structure and function of the multifunctional DNA-repair enzyme exonuclease III. PUBMED:7885481 EPMC:7885481 .
Lahm A, Suck D; , J Mol Biol 1991;222:645-667.: DNase I-induced DNA conformation. 2 A structure of a DNase I-octamer complex. PUBMED:1748997 EPMC:1748997.