Gallus_gallusFamily: GTP_EFTU Number of Genes: 21
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
EFTUD2
EEF1A2
EFL1
RAB35
GFM1
RAB33B
GTPBP2
MRAS
HBS1L
GUF1
GFM2
EEF1A1
-
GPN1
-
EIF5B
GTPBP1
KRAS
MTIF2
EEF2
EEFSEC
GSPT2

Introduction

Pfam

This domain contains a P-loop motif, also found in several other families such as PF00071 PF00025 and PF00063. Elongation factor Tu consists of three structural domains, this plus two C-terminal beta barrel domains.

InterPro

The translational GTPases are the Bacteria elongation factors, EFTu, EFG, and the initiation factor, IF2, and their archaeal homologues, the EF1, EF2, aeIF5b and aeIF2. They all contain two homologous N-terminal domains: a GTPase or G-domain, followed by an OB-domain. These translational proteins' G-domains are both structurally and functionally related to a larger family of GTPase G proteins [PUBMED:11916378].

Reference

  1. Stark H, Rodnina MV, Rinke-Appel J, Brimacombe R, Wintermeyer W, van Heel M; , Nature 1997;389:403-406.: Visualization of elongation factor Tu on the Escherichia coli ribosome. PUBMED:9311785 EPMC:9311785.