Saccharomyces_cerevisiaeFamily: Helicase_Sgs1 Number of Genes: 1
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO



RecQ helicases unwind DNA in an ATP-dependent manner. Sgs1 has a HRDC (helicase and RNaseD C-terminal) domain which modulates the helicase function via auxiliary contacts to DNA [1].


This entry represents a domain found in the fungal Sgs1 protein.


  1. Liu Z, Macias MJ, Bottomley MJ, Stier G, Linge JP, Nilges M, Bork P, Sattler M; , Structure. 1999;7:1557-1566.: The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins. PUBMED:10647186 EPMC:10647186.