Cynoglossus_semilaevisFamily: RIO1 Number of Genes: 19
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
nuak2
dapk2b
MARK1
camk1b
-
mapk12a
phkg1a
nuak1b
mark3a
riok2
-
camk1gb
riok1
-
rps6ka4
mylk5
riok3
camk1da
dapk1
tp53rk

Introduction

Pfam

This is a family of atypical serine kinases which are found in archaea, bacteria and eukaryotes. Activity of Rio1 is vital in Saccharomyces cerevisiae for the processing of ribosomal RNA, as well as for proper cell cycle progression and chromosome maintenance. The structure of RIO1 has been determined [4].

InterPro

No InterPro abstract

Reference

  1. Krupa A, Srinivasan N; , Protein Sci 2002;11:1580-1584.: Lipopolysaccharide phosphorylating enzymes encoded in the genomes of Gram-negative bacteria are related to the eukaryotic protein kinases. PUBMED:12021457 EPMC:12021457 .

  2. Vanrobays E, Gelugne JP, Gleizes PE, Caizergues-Ferrer M; , Mol Cell Biol 2003;23:2083-2095.: Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae. PUBMED:12612080 EPMC:12612080 .

  3. Geerlings TH, Faber AW, Bister M, Vos JC, Raue HA; , 0;0:0-0.: Rio2p: An evolutionarily conserved, low-abundant protein kinase essential for processing of 20S Pre-rRNA in Saccharomyces cerevisiae. PUBMED:12690111 EPMC:12690111 .

  4. Laronde-Leblanc N, Guszczynski T, Copeland T, Wlodawer A; , FEBS J 2005;272:3698-3713.: Structure and activity of the atypical serine kinase Rio1. PUBMED:16008568 EPMC:16008568.