EuRBPDB

Anabas_testudineusFamily: RNA_pol_Rpb1_3 Number of Genes: 3

Ensembl ID	Symbol	Entrez ID
ENSATEG00000016773	polr1a	113161077
ENSATEG00000019644	polr2a	113157222
ENSATEG00000023277	polr3a	113156466

Introduction

Pfam

RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). This domain, domain 3, represents the pore domain. The 3' end of RNA is positioned close to this domain. The pore delimited by this domain is thought to act as a channel through which nucleotides enter the active site and/or where the 3' end of the RNA may be extruded during back-tracking [1,2].

InterPro

The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.

Reference

Severinov K, Mustaev A, Kukarin A, Muzzin O, Bass I, Darst SA, Goldfarb A; , J Biol Chem 1996;271:27969-27974.: Structural modules of the large subunits of RNA polymerase. Introducing archaebacterial and chloroplast split sites in the beta and beta' subunits of Escherichia coli RNA polymerase. PUBMED:8910400 EPMC:8910400 .
Cramer P, Bushnell DA, Kornberg RD; , Science 2001;292:1863-1876.: Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution. PUBMED:11313498 EPMC:11313498.