Saccharomyces_cerevisiaeFamily: Utp13 Number of Genes: 1
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO



Utp13 is a component of the five protein Pwp2 complex that forms part of a stable particle subunit independent of the U3 small nucleolar ribonucleoprotein that is essential for the initial assembly steps of the 90S pre-ribosome [1]. Pwp2 is capable of interacting directly with the 35 S pre-rRNA 5' end [1].


A large ribonuclear protein complex is required for the processing of the small-ribosomal-subunit rRNA - the small-subunit (SSU) processome [PUBMED:12068309, PUBMED:15590835]. This preribosomal complex contains the U3 snoRNA and at least 40 proteins, which have the following properties:


  1. Dosil M, Bustelo XR; , J Biol Chem. 2004;279:37385-37397.: Functional characterization of Pwp2, a WD family protein essential for the assembly of the 90 S pre-ribosomal particle. PUBMED:15231838 EPMC:15231838.