|Ensembl ID||Symbol||Entrez ID||RBD||RBPome||PRI||Expresion||Pathway||Phenotype||Paralog||Ortholog||GO|
This domain is found in prokaryotic methionyl-tRNA synthetases, prokaryotic phenylalanyl tRNA synthetases the yeast GU4 nucleic-binding protein (G4p1 or p42, ARC1)  human tyrosyl-tRNA synthetase  and endothelial-monocyte activating polypeptide II. G4p1 binds specifically to tRNA form a complex with methionyl-tRNA synthetases . In human tyrosyl-tRNA synthetase this domain may direct tRNA to the active site of the enzyme . This domain may perform a common function in tRNA aminoacylation .
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
Kleeman TA, Wei D, Simpson KL, First EA; , J Biol Chem 1997;272:14420-14425.: Human tyrosyl-tRNA synthetase shares amino acid sequence homology with a putative cytokine. PUBMED:9162081 EPMC:9162081 .
Simos G, Segref A, Fasiolo F, Hellmuth K, Shevchenko A, Mann M, Hurt EC; , EMBO J 1996;15:5437-5448.: The yeast protein Arc1p binds to tRNA and functions as a cofactor for the methionyl-and glutamyl-tRNA synthetases. PUBMED:8895587 EPMC:8895587.