Cercocebus_atysFamily: DEAD Number of Genes: 84
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DHX15
-
-
DDX3X
ASCC3
DDX41
POLQ
-
SNRNP200
SMARCA1
DHX16
DHX9
DDX10
DHX33
RECQL5
DHX40
-
-
DDX42
RAD54L
RECQL4
DHX57
HFM1
FANCM
DICER1
YTHDC2
DDX43
CMSS1
IFIH1
-
-
DDX50
-
DDX49
-
-
TDRD9
-
-
-
-
DDX1
DDX51
DDX55
HELQ
-
-
DDX27
DDX17
RECQL
DHX29
DDX18
DHX38
SKIV2L
DHX36
-
-
DDX24
DDX31
-
-
-
DDX60
DDX20
DDX59
-
-
DDX56
-
-
DDX23
-
-
DDX58
-
-
WRN
BLM
DDX5
DDX46
DDX52
BRIP1
EIF4A1
DDX54
MTREX
DDX25
DDX19A
-
DHX58
DDX21
DHX30
DDX39B
DDX60L
DDX4
DDX39A
SMARCA5
-
-
DDX6

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.