Papio_anubisFamily: DEAD Number of Genes: 81
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
POLQ
DDX27
-
SMARCA5
-
DDX56
DDX49
RECQL
SMARCA1
TDRD9
HELQ
DDX25
DDX43
SNRNP200
ASCC3
DDX55
DHX36
DDX51
DDX54
MTREX
HFM1
DDX4
DHX37
SKIV2L
DDX41
DHX9
DHX29
DHX30
-
DDX39A
DDX17
DDX10
RAD54L
DDX47
DDX59
-
-
DDX60L
DDX20
BLM
WRN
DDX39B
-
-
DDX6
DDX23
DDX60
-
DDX18
CMSS1
-
RECQL5
DHX15
DDX5
DDX42
-
-
DHX58
DHX38
DDX52
DDX21
-
BRIP1
DHX40
DDX24
DICER1
FANCM
IFIH1
DDX3X
EIF4A1
DHX57
DHX33
YTHDC2
-
RECQL4
DDX46
DDX1
DDX58
DDX31
-
-
-
-
-
-
-
-
-
-
-
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.