Propithecus_coquereliFamily: DEAD Number of Genes: 64
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
RECQL5
BLM
DDX42
DDX54
DHX33
DDX60
SKIV2L
DDX31
DDX55
EIF4A1
DDX50
DDX59
-
DHX16
RECQL4
-
DDX17
RAD54L
DDX19A
DDX18
DHX57
DDX25
DHX9
MTREX
DDX24
DDX39B
DDX46
-
DDX21
DDX51
EIF4A3
CMSS1
DDX43
DDX10
SMARCA1
-
DDX6
DHX58
-
IFIH1
DHX29
DICER1
EIF4A2
-
DDX41
-
DDX5
-
SNRNP200
DDX28
-
POLQ
DDX56
DDX49
DDX20
DDX27
DHX30
DDX23
-
-
SMARCA5
-
-
DDX58
RECQL
DHX37
DDX3X
DHX38
-
DDX1
DDX47
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.