Aotus_nancymaaeFamily: DEAD Number of Genes: 85
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
-
-
DDX24
DHX29
EIF4A3
DDX5
-
-
DDX3X
-
-
DDX23
SMARCA5
DHX40
TTF2
DHX15
-
DHX36
DDX10
-
-
ASCC3
YTHDC2
DHX38
-
-
-
-
MTREX
SMARCA1
-
DDX19A
DICER1
-
-
-
-
DHX16
POLQ
-
-
RECQL4
DHX30
FANCM
DDX47
-
-
DDX59
-
-
RECQL5
-
-
-
IFIH1
DDX52
DDX43
-
DHX58
DDX4
HFM1
-
-
DHX9
DDX39B
DDX25
DDX60
DDX49
DDX51
DDX58
-
-
DDX46
-
-
WRN
-
-
HELQ
DDX55
-
-
-
-
DDX17
DDX31
-
RECQL
EIF4A1
RAD54L
DDX42
DDX41
DDX27
SNRNP200
-
-
DHX33
DDX20
DDX1
SKIV2L
DDX21
-
BLM

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.