Macaca_nemestrinaFamily: DEAD Number of Genes: 78
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DDX20
DHX16
DICER1
DDX17
DHX29
DDX41
DDX56
DDX55
DDX1
DDX60L
DDX49
DDX46
-
-
DDX60
-
-
BLM
-
DDX50
DDX3X
RECQL
SMARCA5
DDX18
DDX51
SNRNP200
WRN
IFIH1
MTREX
ASCC3
DDX21
DDX4
DDX10
DDX6
DDX25
DHX15
POLQ
DHX30
ERCC6L2
-
EIF4A1
RECQL4
-
DDX42
-
-
DDX43
RAD54L
FANCM
HELQ
-
DDX5
-
-
DHX36
-
-
DHX57
DDX23
RECQL5
DDX59
BRIP1
-
-
YTHDC2
DDX39B
DHX9
SMARCA1
DDX58
-
DDX54
DDX52
-
-
-
DHX40
DDX27
DDX24
DHX58
TDRD9
DDX47
DDX39A
SKIV2L
-
-
DHX38
-
-
DDX31
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.