Mandrillus_leucophaeusFamily: DEAD Number of Genes: 82
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
IFIH1
DDX20
DDX39A
DDX52
-
-
SNRNP200
ERCC6L2
-
DHX30
DDX60L
-
DDX6
DDX27
-
-
DDX21
DDX17
DHX38
-
-
DHX57
DDX58
-
DDX19A
SKIV2L
DDX1
DDX60
DDX31
DHX15
TDRD9
EIF4A1
POLQ
DHX29
DHX36
BLM
EIF4A3
RECQL5
DDX46
CMSS1
DHX33
DICER1
-
-
HELQ
ASCC3
-
-
FANCM
RECQL4
-
-
DDX50
BRIP1
DDX18
RAD54L
DDX4
WRN
DDX54
DDX55
DDX24
RECQL
DHX9
-
-
-
DDX41
MTREX
DDX5
DDX25
DDX43
-
DDX59
SMARCA5
-
DDX49
DHX58
DDX23
-
DHX37
DHX40
DDX42
YTHDC2
SMARCA1
DDX56
DDX39B
DHX16
-
-
DDX10
DDX3X

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.