Pongo_abeliiFamily: DEAD Number of Genes: 69
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DHX9
DDX20
-
HFM1
RAD54L
-
DDX21
DDX50
DDX10
-
DDX6
DDX25
-
DDX47
RECQL
DDX23
DDX54
DDX55
-
DDX51
-
FANCM
-
DDX24
DICER1
BLM
-
DDX28
DHX38
-
-
DHX33
EIF4A1
DDX52
DDX42
DDX5
RECQL5
EIF4A3
DHX40
-
DDX39A
DDX49
-
DDX27
DDX17
SNRNP200
-
DHX57
-
DDX1
DDX18
IFIH1
-
POLQ
DHX30
-
-
EIF4A2
DHX15
-
HELQ
SMARCA5
-
DDX60
-
DDX60L
-
DHX29
MTREX
-
DDX4
YTHDC2
-
DDX46
-
DDX41
-
DHX16
DDX39B
SKIV2L
-
DDX43
ASCC3
-
DDX56
-
WRN
-
RECQL4
DDX58
-
-
DDX31
-
DDX53
DDX3X
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.