Est1 is a protein which recruits or activates telomerase at the site of polymerisation . This is the DNA/RNA binding domain of EST1 .
This entry represents a DNA/RNA binding domain found in the telomere elongation protein EST1 and related sequences, such as the nonsense-mediated mRNA decay pathway proteins SMG5 and SMG7 [PUBMED:12676088, PUBMED:14636577, PUBMED:15546618].
Evans SK, Lundblad V; , Genetics. 2002;162:1101-1115.: The Est1 subunit of Saccharomyces cerevisiae telomerase makes multiple contributions to telomere length maintenance. PUBMED:12454059 EPMC:12454059 .