Dasypus_novemcinctusFamily: DEAD Number of Genes: 71
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DDX50
DDX21
RECQL4
RAD54L
DHX37
DDX58
DHX9
DICER1
-
-
SMARCA1
HFM1
DDX55
DDX24
-
DDX17
DHX38
DDX1
-
FANCM
DDX42
DDX25
DDX60
WRN
EIF4A3
POLQ
DDX31
BLM
-
DDX39B
ASCC3
-
SNRNP200
DDX46
-
DDX4
IFIH1
YTHDC2
DDX10
-
RECQL
DDX51
DHX15
DDX6
DHX29
MTREX
DHX57
DHX33
-
-
DDX59
-
DDX27
DHX40
DDX20
-
-
DDX54
-
-
DDX28
-
-
-
DDX56
SKIV2L
-
CMSS1
DDX47
-
-
DHX58
DDX23
-
-
EIF4A1
DDX41
DDX52
DDX39A
-
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.