Macaca_fascicularisFamily: DEAD Number of Genes: 80
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
FANCM
DDX52
TDRD9
POLQ
ASCC3
SMARCA1
DICER1
DHX15
DHX16
HFM1
DHX29
IFIH1
DDX60
-
-
DDX5
DDX19A
DDX51
RAD54L
DDX42
RECQL
MTREX
DDX20
DDX41
DHX38
-
-
DHX36
-
-
DDX24
DHX30
DDX1
-
-
DDX39B
SKIV2L
DHX58
DDX3X
DDX59
-
-
DDX31
DHX37
-
-
DDX19B
DDX55
RECQL4
DDX23
EIF4A1
DDX25
DHX57
SNRNP200
DDX4
HELQ
DDX56
DHX9
DHX40
DDX6
-
DDX47
DHX33
-
-
BLM
DDX18
DDX43
WRN
DDX54
SMARCA5
EIF4A3
DDX50
BRIP1
DDX39A
DDX46
RECQL5
EIF4A2
DDX49
-
DDX21
CMSS1
DDX60L
DDX58
DDX27
-
DDX10
DDX17

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.