Ovis_ariesFamily: DEAD Number of Genes: 71
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
WRN
-
-
-
RAD54L
-
-
DDX3X
HELQ
DDX52
DHX33
-
DDX28
-
DDX55
-
DHX36
DHX38
-
-
-
-
-
-
DDX50
DDX21
DDX41
DDX39A
-
DDX31
-
DHX15
IFIH1
TDRD9
-
DDX4
-
MTREX
DHX29
DDX54
-
ERCC6L2
-
DHX57
-
DDX39B
FANCM
-
-
RECQL5
-
SMARCA5
-
-
DDX6
ASCC3
-
DDX25
DDX51
-
DDX18
DDX27
-
DHX40
DDX10
-
BLM
RECQL4
-
DDX42
SNRNP200
-
DDX24
DDX46
-
EIF4A1
-
SMARCA1
-
DDX58
DDX5
DDX56
-
DICER1
-
DDX17
-
HFM1
-
YTHDC2
-
DDX59
DDX1
-
-
-
-
DHX58
-
-
DHX9
-
DDX23
DDX20
POLQ
-
RECQL
-
DDX47

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.