Panthera_pardusFamily: DEAD Number of Genes: 75
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DHX16
DDX41
DICER1
YTHDC2
DDX39B
DHX15
-
-
BLM
DDX42
DHX36
HFM1
-
-
DDX39A
DHX57
SNRNP200
RECQL5
-
SMARCA5
DHX58
SKIV2L
DHX37
DDX54
DDX3X
DDX25
DHX9
DDX10
DDX18
DDX27
EIF4A1
-
POLQ
DDX24
EIF4A2
DDX17
SMARCA1
DHX38
DDX6
DHX33
DDX60
DDX52
DDX19A
DHX40
DDX58
RAD54L
RECQL
HELQ
DDX46
WRN
-
-
ASCC3
DDX4
-
-
DDX55
DDX21
-
-
DDX49
DDX43
DDX56
DDX51
DDX23
DDX50
DDX59
CMSS1
DDX47
-
-
DDX28
ERCC6L2
-
MTREX
DDX1
TDRD9
EIF4A3
-
DHX30
DDX20
DHX29
IFIH1

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.